Identification
Name:Lysophospholipase L2
Synonyms:
  • Lecithinase B
Gene Name:pldB
Enzyme Class:
Biological Properties
General Function:Lipid transport and metabolism
Specific Function:2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate
Cellular Location:Cell inner membrane; Peripheral membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.01-Acyl-sn-glycero-3-phosphocholine+1.0Thumb1.0Thumb+1.0Thumb
1.01-Acyl-sn-glycero-3-phosphocholine + 1.0Water ↔ 1.0Glycerophosphocholine + 1.0Carboxylate
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb ? 1.0a carboxylate+1.0Thumb+1.0Thumb
Complex Reactions:
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+2.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+2.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+2.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+2.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+2.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb1.0Thumb+2.0Thumb+1.0Thumb
Metabolites:
ECMDB IDNameView
ECMDB211392-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0)MetaboCard
ECMDB211402-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)MetaboCard
ECMDB211412-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:1)MetaboCard
ECMDB211422-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)MetaboCard
ECMDB211432-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:1)MetaboCard
ECMDB211442-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)MetaboCard
ECMDB211452-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:1)MetaboCard
ECMDB211462-Acyl-sn-glycero-3-phosphoglycerol (n-C12:0)MetaboCard
ECMDB211472-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0)MetaboCard
ECMDB211482-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)MetaboCard
ECMDB211492-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)MetaboCard
ECMDB211502-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)MetaboCard
ECMDB211512-Acyl-sn-glycero-3-phosphoglycerol (N-C18:0)MetaboCard
ECMDB211522-Acyl-sn-glycero-3-phosphoglycerol (N-C18:1)MetaboCard
ECMDB040052-AcylglycerophosphocholineMetaboCard
ECMDB211592-dodecanoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB211602-hexadec-9-enoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB211612-hexadecanoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB211622-octadec-11-enoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB211632-octadecanoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB211652-tetradec-7-enoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB211662-tetradecanoyl-sn-glycerol 3-phosphateMetaboCard
ECMDB21302Acyl phosphatidylglycerol (N-C14:1)MetaboCard
ECMDB21304Acyl phosphatidylglycerol (N-C16:1)MetaboCard
ECMDB21306Acyl phosphatidylglycerol (N-C18:1)MetaboCard
ECMDB21209Dodecanoate (N-C12:0)MetaboCard
ECMDB00126Glycerol 3-phosphateMetaboCard
ECMDB00086GlycerophosphocholineMetaboCard
ECMDB21223GlycerophosphoglycerolMetaboCard
ECMDB00114GlycerylphosphorylethanolamineMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB21347Octadecanoate (N-C18:0)MetaboCard
ECMDB21348Octadecenoate (N-C18:1)MetaboCard
ECMDB00220Palmitic acidMetaboCard
ECMDB23632PG(10:0(3-OH)/10:0(3-OH))MetaboCard
ECMDB23631PG(10:0(3-OH)/10:0)MetaboCard
ECMDB23634PG(10:0(3-OH)/12:0(3-OH))MetaboCard
ECMDB23633PG(10:0(3-OH)/12:0)MetaboCard
ECMDB23636PG(10:0(3-OH)/14:0(3-OH))MetaboCard
ECMDB23635PG(10:0(3-OH)/14:0)MetaboCard
ECMDB23637PG(10:0(3-OH)/15:0)MetaboCard
ECMDB23638PG(10:0(3-OH)/15:0cyclo)MetaboCard
ECMDB23639PG(10:0(3-OH)/16:0)MetaboCard
ECMDB23640PG(10:0(3-OH)/16:1(9Z))MetaboCard
ECMDB23641PG(10:0(3-OH)/17:0cycw7c)MetaboCard
ECMDB23642PG(10:0(3-OH)/18:1(9Z))MetaboCard
ECMDB23643PG(10:0(3-OH)/19:0cycv8c)MetaboCard
ECMDB23644PG(10:0(3-OH)/19:iso)MetaboCard
ECMDB23645PG(10:0/10:0(3-OH))MetaboCard
ECMDB23646PG(10:0/12:0(3-OH))MetaboCard
ECMDB23647PG(10:0/14:0(3-OH))MetaboCard
ECMDB23648PG(10:0/19:iso)MetaboCard
ECMDB23650PG(12:0(3-OH)/10:0(3-OH))MetaboCard
ECMDB23649PG(12:0(3-OH)/10:0)MetaboCard
ECMDB23652PG(12:0(3-OH)/12:0(3-OH))MetaboCard
ECMDB23651PG(12:0(3-OH)/12:0)MetaboCard
ECMDB23654PG(12:0(3-OH)/14:0(3-OH))MetaboCard
ECMDB23653PG(12:0(3-OH)/14:0)MetaboCard
ECMDB23655PG(12:0(3-OH)/15:0)MetaboCard
ECMDB23656PG(12:0(3-OH)/15:0cyclo)MetaboCard
ECMDB23657PG(12:0(3-OH)/16:0)MetaboCard
ECMDB23658PG(12:0(3-OH)/16:1(9Z))MetaboCard
ECMDB23659PG(12:0(3-OH)/17:0cycw7c)MetaboCard
ECMDB23660PG(12:0(3-OH)/18:1(9Z))MetaboCard
ECMDB23661PG(12:0(3-OH)/19:0cycv8c)MetaboCard
ECMDB23662PG(12:0(3-OH)/19:iso)MetaboCard
ECMDB23663PG(12:0/10:0(3-OH))MetaboCard
ECMDB23664PG(12:0/12:0(3-OH))MetaboCard
ECMDB21265PG(12:0/12:0)MetaboCard
ECMDB23665PG(12:0/14:0(3-OH))MetaboCard
ECMDB23666PG(12:0/19:iso)MetaboCard
ECMDB23668PG(14:0(3-OH)/10:0(3-OH))MetaboCard
ECMDB23667PG(14:0(3-OH)/10:0)MetaboCard
ECMDB23670PG(14:0(3-OH)/12:0(3-OH))MetaboCard
ECMDB23669PG(14:0(3-OH)/12:0)MetaboCard
ECMDB23672PG(14:0(3-OH)/14:0(3-OH))MetaboCard
ECMDB23671PG(14:0(3-OH)/14:0)MetaboCard
ECMDB23673PG(14:0(3-OH)/15:0)MetaboCard
ECMDB23674PG(14:0(3-OH)/15:0cyclo)MetaboCard
ECMDB23675PG(14:0(3-OH)/16:0)MetaboCard
ECMDB23676PG(14:0(3-OH)/16:1(9Z))MetaboCard
ECMDB23677PG(14:0(3-OH)/17:0cycw7c)MetaboCard
ECMDB23678PG(14:0(3-OH)/18:1(9Z))MetaboCard
ECMDB23679PG(14:0(3-OH)/19:0cycv8c)MetaboCard
ECMDB23680PG(14:0(3-OH)/19:iso)MetaboCard
ECMDB23681PG(14:0/10:0(3-OH))MetaboCard
ECMDB23682PG(14:0/12:0(3-OH))MetaboCard
ECMDB23683PG(14:0/14:0(3-OH))MetaboCard
ECMDB21013PG(14:0/14:0)MetaboCard
ECMDB23684PG(14:0/19:iso)MetaboCard
ECMDB21266PG(14:1(7Z)/14:1(7Z))MetaboCard
ECMDB23685PG(15:0/10:0(3-OH))MetaboCard
ECMDB23686PG(15:0/12:0(3-OH))MetaboCard
ECMDB23687PG(15:0/14:0(3-OH))MetaboCard
ECMDB23688PG(15:0/19:iso)MetaboCard
ECMDB23689PG(15:0cyclo/10:0(3-OH))MetaboCard
ECMDB23690PG(15:0cyclo/12:0(3-OH))MetaboCard
ECMDB23691PG(15:0cyclo/14:0(3-OH))MetaboCard
ECMDB23692PG(15:0cyclo/19:iso)MetaboCard
ECMDB23693PG(16:0/10:0(3-OH))MetaboCard
ECMDB23694PG(16:0/12:0(3-OH))MetaboCard
ECMDB23695PG(16:0/14:0(3-OH))MetaboCard
ECMDB10570PG(16:0/16:0)MetaboCard
ECMDB23696PG(16:0/19:iso)MetaboCard
ECMDB23697PG(16:1(9Z)/10:0(3-OH))MetaboCard
ECMDB23698PG(16:1(9Z)/12:0(3-OH))MetaboCard
ECMDB23699PG(16:1(9Z)/14:0(3-OH))MetaboCard
ECMDB10586PG(16:1(9Z)/16:1(9Z))MetaboCard
ECMDB23700PG(16:1(9Z)/19:iso)MetaboCard
ECMDB23701PG(17:0cycw7c/10:0(3-OH))MetaboCard
ECMDB23702PG(17:0cycw7c/12:0(3-OH))MetaboCard
ECMDB23703PG(17:0cycw7c/14:0(3-OH))MetaboCard
ECMDB23704PG(17:0cycw7c/19:iso)MetaboCard
ECMDB21267PG(18:0/18:0)MetaboCard
ECMDB10618PG(18:1(11Z)/18:1(11Z))MetaboCard
ECMDB23705PG(18:1(9Z)/10:0(3-OH))MetaboCard
ECMDB23706PG(18:1(9Z)/12:0(3-OH))MetaboCard
ECMDB23707PG(18:1(9Z)/14:0(3-OH))MetaboCard
ECMDB23708PG(18:1(9Z)/19:iso)MetaboCard
ECMDB23709PG(19:0cycv8c/10:0(3-OH))MetaboCard
ECMDB23710PG(19:0cycv8c/12:0(3-OH))MetaboCard
ECMDB23711PG(19:0cycv8c/14:0(3-OH))MetaboCard
ECMDB23712PG(19:0cycv8c/19:iso)MetaboCard
ECMDB23714PG(19:iso/10:0(3-OH))MetaboCard
ECMDB23713PG(19:iso/10:0)MetaboCard
ECMDB23716PG(19:iso/12:0(3-OH))MetaboCard
ECMDB23715PG(19:iso/12:0)MetaboCard
ECMDB23718PG(19:iso/14:0(3-OH))MetaboCard
ECMDB23717PG(19:iso/14:0)MetaboCard
ECMDB23719PG(19:iso/15:0)MetaboCard
ECMDB23720PG(19:iso/15:0cyclo)MetaboCard
ECMDB23721PG(19:iso/16:0)MetaboCard
ECMDB23722PG(19:iso/16:1(9Z))MetaboCard
ECMDB23723PG(19:iso/17:0cycw7c)MetaboCard
ECMDB23724PG(19:iso/18:1(9Z))MetaboCard
ECMDB23725PG(19:iso/19:0cycv8c)MetaboCard
ECMDB23726PG(19:iso/19:iso)MetaboCard
ECMDB21361tetradecanoate (n-C14:0)MetaboCard
ECMDB21362Tetradecenoate (N-C14:1)MetaboCard
ECMDB00494WaterMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b3825
Gene OrientationClockwise
Centisome Percentage:86.37
Left Sequence End4007193
Right Sequence End4008215
Gene Sequence:
>1023 bp
ATGAAAAAAGTGTTATTGATAATCTTGTTATTGCTGGTGGTACTGGGTATCGCCGCTGGT
GTGGGCGTCTGGAAGGTTCGCCATCTTGCCGACAGCAAATTGCTTATCAAAGAAGAGACG
ATATTTACCCTGAAGCCAGGGACCGGACGTCTGGCGCTCGGTGAACAGCTTTATGCCGAT
AAGATCATCAATCGTCCACGGGTTTTTCAATGGCTGCTGCGTATCGAACCGGATCTTTCT
CACTTTAAAGCCGGGACTTACCGCTTTACACCGCAGATGACCGTGCGCGAGATGCTGAAA
TTGCTGGAAAGCGGTAAAGAAGCACAGTTCCCTCTGCGACTGGTAGAAGGGATGCGTCTG
AGCGATTACCTCAAGCAATTGCGTGAGGCCCCGTATATCAAGCATACGCTGAGCGATGAT
AAGTACGCCACCGTAGCGCAGGCACTTGAACTGGAAAACCCGGAGTGGATTGAAGGTTGG
TTCTGGCCAGACACCTGGATGTATACCGCCAATACCACCGATGTCGCGTTACTCAAGCGA
GCGCACAAGAAAATGGTGAAAGCGGTCGATAGCGCCTGGGAAGGGCGTGCGGACGGTCTG
CCTTATAAAGATAAAAACCAGTTGGTGACGATGGCATCAATTATCGAAAAAGAAACCGCC
GTTGCCAGTGAACGCGATAAGGTTGCCTCAGTATTTATCAACCGTTTACGCATTGGTATG
CGCCTGCAGACCGACCCGACCGTGATTTACGGGATGGGAGAGCGTTATAATGGCAAACTT
TCTCGTGCAGACCTGGAAACGCCGACAGCGTATAACACCTATACCATTACCGGTCTGCCG
CCAGGTGCGATAGCGACGCCGGGGGCGGATTCGCTGAAGGCTGCTGCGCATCCGGCAAAA
ACGCCGTATCTCTATTTTGTGGCCGATGGTAAAGGTGGTCACACGTTTAATACCAATCTT
GCCAGTCATAACAAGTCTGTGCAGGATTATCTGAAAGTGCTTAAGGAAAAAAATGCGCAG
TAA
Protein Properties
Pfam Domain Function:
Protein Residues:340
Protein Molecular Weight:38978
Protein Theoretical pI:8
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Lysophospholipase L2
MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVRFVRFRAQHHDRVVVIC
PGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADPHLGHVNRFNDYVDDLAAF
WQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIALTAPMFGIVIRMPSFMARQI
LNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRYRRNLRFYADDPTIRVGGPTYHW
VRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNRMHDRFCELRTAAGHPVEGGRPLVI
KGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSGNRSTEV
References
External Links:
ResourceLink
Uniprot ID:P07000
Uniprot Name:PLDB_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674836
Ecogene ID:EG10739
Ecocyc:EG10739
ColiBase:b3825
Kegg Gene:b3825
EchoBASE ID:EB0732
CCDB:PLDB_ECOLI
BacMap:49176423
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Daniels, D. L., Plunkett, G. 3rd, Burland, V., Blattner, F. R. (1992). "Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes." Science 257:771-778. Pubmed: 1379743
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Kobayashi, T., Kudo, I., Karasawa, K., Mizushima, H., Inoue, K., Nojima, S. (1985). "Nucleotide sequence of the pldB gene and characteristics of deduced amino acid sequence of lysophospholipase L2 in Escherichia coli." J Biochem 98:1017-1025. Pubmed: 3908445
  • Riley, M., Abe, T., Arnaud, M. B., Berlyn, M. K., Blattner, F. R., Chaudhuri, R. R., Glasner, J. D., Horiuchi, T., Keseler, I. M., Kosuge, T., Mori, H., Perna, N. T., Plunkett, G. 3rd, Rudd, K. E., Serres, M. H., Thomas, G. H., Thomson, N. R., Wishart, D., Wanner, B. L. (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34:1-9. Pubmed: 16397293