Dodecanoate (N-C12:0) (ECMDB21209) (M2MDB001617)

General function:

Lipid transport and metabolism

Specific function:

2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate

Gene Name:

pldB

Uniprot ID:

P07000

Molecular weight:

38978

Reactions

General function:

Involved in phospholipase activity

Specific function:

Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant in normal growing cells. Required for efficient secretion of bacteriocins

Gene Name:

pldA

Uniprot ID:

P0A921

Molecular weight:

33163

Reactions

General function:

Involved in acylphosphatase activity

Specific function:

An acylphosphate + H(2)O = a carboxylate + phosphate

Gene Name:

yccX

Uniprot ID:

P0AB65

Molecular weight:

10300

Reactions

General function:

Involved in hydrolase activity

Specific function:

Hydrolyzes only long chain acyl thioesters (C12-C18). Specificity similar to chymotrypsin

Gene Name:

tesA

Uniprot ID:

P0ADA1

Molecular weight:

23622

Reactions

General function:

Involved in [acyl-carrier-protein] phosphodiesterase activity

Specific function:

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP

Gene Name:

acpH

Uniprot ID:

P21515

Molecular weight:

22961

Reactions

General function:

Involved in transferase activity, transferring acyl groups

Specific function:

Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1

Gene Name:

aas

Uniprot ID:

P31119

Molecular weight:

80699

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids

Gene Name:

fadD

Uniprot ID:

P69451

Molecular weight:

62332

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes the esterification, concomitant with transport, of exogenous fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. It has a low activity on medium or long chain fatty acids and is maximally active on C6 and C8 substrates

Gene Name:

fadK

Uniprot ID:

P38135

Molecular weight:

60773

Reactions

General function:

Involved in acyl-CoA hydrolase activity

Specific function:

Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known

Gene Name:

tesB

Uniprot ID:

P0AGG2

Molecular weight:

31966

General function:

Involved in fatty acid biosynthetic process

Specific function:

Carrier of the growing fatty acid chain in fatty acid biosynthesis

Gene Name:

acpP

Uniprot ID:

P0A6A8

Molecular weight:

8640