PG(19:0cycv8c/19:iso) (ECMDB23712) (M2MDB004102)

General function:

Lipid transport and metabolism

Specific function:

2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate

Gene Name:

pldB

Uniprot ID:

P07000

Molecular weight:

38978

Reactions

General function:

Involved in catalytic activity

Specific function:

Hydrolyzes phosphatidylglycerophosphate, phosphatidic acid, and lysophosphatidic acid; the pattern of activities varies according to subcellular location

Gene Name:

pgpB

Uniprot ID:

P0A924

Molecular weight:

29021

Reactions

General function:

Involved in phosphatidylglycerophosphatase activity

Specific function:

One of the three phospholipid phosphatases, specifically hydrolyzes phosphatidylglycerophosphate

Gene Name:

pgpA

Uniprot ID:

P18200

Molecular weight:

19418

Reactions

General function:

Involved in nucleotide binding

Specific function:

Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation

Gene Name:

msbA

Uniprot ID:

P60752

Molecular weight:

64460

General function:

Not Available

Specific function:

Not known; overproduction leads to camphor resistance and chromosome condensation

Gene Name:

crcA

Uniprot ID:

P37001

Molecular weight:

21770

General function:

Involved in phosphotransferase activity, for other substituted phosphate groups

Specific function:

Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Affects resistance to the gyrase inhibitor novobiocin

Gene Name:

cls

Uniprot ID:

P0A6H8

Molecular weight:

54822

Reactions

General function:

Involved in catalytic activity

Specific function:

Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate. Catalyzes little, if any, cardiolipin synthesis in vivo, even when the expression level is very high

Gene Name:

ybhO

Uniprot ID:

P0AA84

Molecular weight:

47633

Reactions

General function:

cardiolipin biosynthetic process

Specific function:

Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE).

Gene Name:

clsC

Uniprot ID:

P75919

Molecular weight:

53665

Reactions