ECMDB

Identification

Name:

Protein mazG

Synonyms:

Not Available

Gene Name:

mazG

Enzyme Class:

3.6.1.8

Biological Properties

General Function:

Involved in nucleoside-triphosphate diphosphatase activity

Specific Function:

Specific function unknown

Cellular Location:

Not Available

SMPDB Pathways:

Pyrimidine metabolism PW000942

KEGG Pathways:

Metabolic pathways eco01100
Purine metabolism ec00230
Pyrimidine metabolism ec00240

KEGG Reactions:

1.0

→

1.0

1.0Guanosine triphosphate + 1.0Water → 1.0Guanosine monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0dGTP + 1.0Water → 1.02'-Deoxyguanosine 5'-monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0Cytidine triphosphate + 1.0Water → 1.0Cytidine monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

2.0

1.0

1.0Water + 1.0UDP-Glucose → 1.0Glucose 1-phosphate + 2.0Hydrogen ion + 1.0Uridine 5'-monophosphate
ReactionCard

1.0

→

1.0

1.0Water + 1.0Uridine triphosphate → 1.0Hydrogen ion + 1.0Pyrophosphate + 1.0Uridine 5'-monophosphate
ReactionCard

1.0

↔

1.0

1.0Adenosine triphosphate + 1.0Water ↔ 1.0Adenosine monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0Water + 1.0Inosine triphosphate → 1.0Hydrogen ion + 1.0Inosinic acid + 1.0Pyrophosphate
ReactionCard

1.0

↔

1.0

1.0Adenosine triphosphate + 1.0Water ↔ 1.0ADP + 1.0Phosphate
ReactionCard

1.0

↔

1.0

1.0Adenosine triphosphate + 1.0Water ↔ 1.0Adenosine monophosphate + 1.0Pyrophosphate
ReactionCard

1.0

↔

1.0

1.0UDP-Glucose + 1.0Water ↔ 1.0Uridine 5'-monophosphate + 1.0Glucose 1-phosphate
ReactionCard

1.0

↔

1.0

1.0Guanosine triphosphate + 1.0Water ↔ 1.0Guanosine monophosphate + 1.0Pyrophosphate
ReactionCard

1.0

↔

1.0

1.0Cytidine triphosphate + 1.0Water ↔ 1.0Cytidine monophosphate + 1.0Pyrophosphate
ReactionCard

1.0

↔

1.0

1.0Uridine triphosphate + 1.0Water ↔ 1.0Uridine 5'-monophosphate + 1.0Pyrophosphate
ReactionCard

1.0

↔

1.0

1.0Inosine triphosphate + 1.0Water ↔ 1.0Inosinic acid + 1.0Pyrophosphate
ReactionCard

SMPDB Reactions:

1.0

→

1.0

1.0Deoxyuridine triphosphate + 1.0Water → 1.0Phosphate + 1.0Hydrogen ion + 1.0dUMP
ReactionCard

EcoCyc Reactions:

1.0

→

1.0

1.0dGTP + 1.0Water → 1.02'-Deoxyguanosine 5'-monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0Cytidine triphosphate + 1.0Water → 1.0Cytidine monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0dATP + 1.0Water → 1.0Deoxyadenosine monophosphate + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0dCTP + 1.0Water → 1.0dCMP + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0Thymidine 5'-triphosphate + 1.0Water → 1.05-Thymidylic acid + 1.0Hydrogen ion + 1.0Pyrophosphate
ReactionCard

1.0

→

1.0

1.0Water + 1.0Inosine triphosphate → 1.0Hydrogen ion + 1.0Inosinic acid + 1.0Pyrophosphate
ReactionCard

Complex Reactions:

1.0

→

1.0

1.0Adenosine triphosphate + 1.0Water → 1.0Adenosine monophosphate + 1.0Pyrophosphate
ReactionCard

Metabolites:

ECMDB ID	Name	View
ECMDB01044	2'-Deoxyguanosine 5'-monophosphate	MetaboCard
ECMDB01227	5-Thymidylic acid	MetaboCard
ECMDB00045	Adenosine monophosphate	MetaboCard
ECMDB00538	Adenosine triphosphate	MetaboCard
ECMDB01341	ADP	MetaboCard
ECMDB00095	Cytidine monophosphate	MetaboCard
ECMDB00082	Cytidine triphosphate	MetaboCard
ECMDB01532	dATP	MetaboCard
ECMDB01202	dCMP	MetaboCard
ECMDB00998	dCTP	MetaboCard
ECMDB00905	Deoxyadenosine monophosphate	MetaboCard
ECMDB01191	Deoxyuridine triphosphate	MetaboCard
ECMDB01440	dGTP	MetaboCard
ECMDB01409	dUMP	MetaboCard
ECMDB01586	Glucose 1-phosphate	MetaboCard
ECMDB01397	Guanosine monophosphate	MetaboCard
ECMDB01273	Guanosine triphosphate	MetaboCard
ECMDB21225	Hydrogen ion	MetaboCard
ECMDB00189	Inosine triphosphate	MetaboCard
ECMDB04085	Inosinic acid	MetaboCard
ECMDB01429	Phosphate	MetaboCard
ECMDB04142	Pyrophosphate	MetaboCard
ECMDB01342	Thymidine 5'-triphosphate	MetaboCard
ECMDB04171	UDP-Glucose	MetaboCard
ECMDB00288	Uridine 5'-monophosphate	MetaboCard
ECMDB00285	Uridine triphosphate	MetaboCard
ECMDB00494	Water	MetaboCard

GO Classification:

Not Available

Gene Properties

Blattner:

b2781

Gene Orientation

Counterclockwise

Centisome Percentage:

62.67

Left Sequence End

2907916

Right Sequence End

2908707

Gene Sequence:

>792 bp
ATGCCTGAAGGCCCGGAGATCCGCCGTGCAGCGGATAACCTGGAGGCGGCGATCAAAGGC
AAACCACTAACTGATGTCTGGTTTGCCTTCCCGCAGTTAAAACCTTATCAATCACAACTT
ATCGGTCAACACGTTACCCATGTGGAAACGCGTGGTAAGGCGTTGTTAACTCATTTTTCC
AACGACTTAACGCTCTACAGCCATAATCAGCTTTACGGCGTCTGGCGCGTGGTTGATACC
GGCGAAGAGCCGCAGACCACGCGAGTATTGCGGGTAAAACTGCAAACGGCTGACAAAACC
ATTCTGCTTTATAGCGCCTCGGATATTGAGATGTTGACCCCGGAACAACTGACCACGCAT
CCGTTTTTACAACGCGTTGGTCCCGATGTGCTGGATCCGAATCTGACGCCGGAGGTGGTG
AAAGAACGATTATTGTCGCCGCGCTTTCGTAACCGTCAGTTTGCTGGATTACTGCTCGAT
CAGGCGTTTCTGGCTGGGCTTGGCAATTATTTGCGGGTGGAGATCCTCTGGCAGGTTGGG
TTGACTGGAAATCATAAAGCGAAAGATCTCAATGCGGCGCAACTGGATGCACTCGCACAC
GCGTTACTGGAGATTCCTCGATTTTCCTACGCTACGCGGGGGCAGGTGGATGAGAATAAG
CATCATGGGGCGCTGTTTCGCTTTAAGGTTTTTCATCGAGATGGCGAACCGTGCGAACGT
TGTGGCAGCATCATTGAGAAAACCACGCTGTCATCTCGCCCGTTTTACTGGTGCCCTGGC
TGCCAGCACTAG

Protein Properties

Pfam Domain Function:

MazG (PF03819 )

Protein Residues:

263

Protein Molecular Weight:

30412

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

None

Protein Sequence:

>Protein mazG
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELG
DLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKT
EERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEA
RQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLE
MTGVDLETMEEVWQQVKRQEIDL

References

External Links:

Resource	Link
Uniprot ID:	P0AEY3
Uniprot Name:	MAZG_ECOLI
GenBank Gene ID:	AP009048
Genebank Protein ID:	4062310
Ecogene ID:	EG10572
Ecocyc:	EG10572
ColiBase:	b2781
Kegg Gene:	b2781
EchoBASE ID:	EB0567
CCDB:	MAZG_ECOLI
BacMap:	16130688

General Reference:

Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553

Protein mazG (P0AEY3)