Bifunctional protein aas (P31119)

Identification
Name:Bifunctional protein aas
Synonyms:
  • 2-acylglycerophosphoethanolamine acyltransferase
  • 2-acyl-GPE acyltransferase
  • Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase
  • Acyl-[acyl-carrier-protein] synthetase
  • Acyl-ACP synthetase
  • Long-chain-fatty-acid--[acyl-carrier-protein] ligase
Gene Name:aas
Enzyme Class:
Biological Properties
General Function:Involved in transferase activity, transferring acyl groups
Specific Function:Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Long-chain fatty acid+1.0Acyl-carrier protein ↔ 1.0Thumb+1.0Thumb+1.0Acyl-[acyl-carrier protein]
1.0Adenosine triphosphate + 1.0Long-chain fatty acid + 1.0Acyl-carrier protein ↔ 1.0Adenosine monophosphate + 1.0Pyrophosphate + 1.0Acyl-[acyl-carrier protein]
ReactionCard
1.0Acyl-[acyl-carrier protein]+1.02-Acyl-sn-glycero-3-phosphoethanolamine+1.0Acyl-[acyl-carrier protein] ↔ 1.0Acyl-carrier protein+1.0Thumb+1.0Acyl-carrier protein
1.0Acyl-[acyl-carrier protein] + 1.02-Acyl-sn-glycero-3-phosphoethanolamine + 1.0Acyl-[acyl-carrier protein] ↔ 1.0Acyl-carrier protein + 1.0PE(14:0/14:0) + 1.0Acyl-carrier protein
ReactionCard
SMPDB Reactions:
1.0Thumb+1.0a holo-[acyl-carrier protein]+1.0Thumb → 1.0Octanoyl-[acyl-carrier protein] +1.0Thumb+1.0Pyrophosphate
1.0Caprylic acid + 1.0a holo-[acyl-carrier protein] + 1.0Adenosine triphosphate → 1.0Octanoyl-[acyl-carrier protein] + 1.0Adenosine monophosphate + 1.0Pyrophosphate
ReactionCard
Complex Reactions:
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Palmitoyl-ACP (n-C16:0ACP)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Palmitic acid → 1.0Adenosine monophosphate + 1.0Palmitoyl-ACP (n-C16:0ACP) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Octanoyl-ACP (n-C8:0ACP)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Caprylic acid → 1.0Adenosine monophosphate + 1.0Octanoyl-ACP (n-C8:0ACP) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Decanoyl-ACP (n-C10:0ACP)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Decanoate (N-C10:0) → 1.0Adenosine monophosphate + 1.0Decanoyl-ACP (n-C10:0ACP) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Dodecanoyl-ACP (n-C12:0ACP)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Dodecanoate (N-C12:0) → 1.0Adenosine monophosphate + 1.0Dodecanoyl-ACP (n-C12:0ACP) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Octadecanoyl-ACP (n-C18:0ACP)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Octadecanoate (N-C18:0) → 1.0Adenosine monophosphate + 1.0Octadecanoyl-ACP (n-C18:0ACP) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Octadecenoate (N-C18:1) → 1.0Adenosine monophosphate + 1.0cis-octadec-11-enoyl-[acyl-carrier protein] (n-C18:1) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Myristoyl-ACP (n-C14:0ACP)+1.0Thumb
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0tetradecanoate (n-C14:0) → 1.0Adenosine monophosphate + 1.0Myristoyl-ACP (n-C14:0ACP) + 1.0Pyrophosphate
ReactionCard
1.0acyl carrier protein+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
1.0acyl carrier protein + 1.0Adenosine triphosphate + 1.0Tetradecenoate (N-C14:1) → 1.0Adenosine monophosphate + 1.0Pyrophosphate + 1.0cis-tetradec-7-enoyl-[acyl-carrier protein] (n-C14:1)
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0) + 1.0Adenosine triphosphate + 1.0Dodecanoate (N-C12:0) → 1.0Adenosine monophosphate + 1.0PE(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0) + 1.0Adenosine triphosphate + 1.0tetradecanoate (n-C14:0) → 1.0Adenosine monophosphate + 1.0PE(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:1) + 1.0Adenosine triphosphate + 1.0Tetradecenoate (N-C14:1) → 1.0Adenosine monophosphate + 1.0PE(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0) + 1.0Adenosine triphosphate + 1.0Palmitic acid → 1.0Adenosine monophosphate + 1.0PE(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0) + 1.0Adenosine triphosphate + 1.0Octadecanoate (N-C18:0) → 1.0Adenosine monophosphate + 1.0PE(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:1) + 1.0Adenosine triphosphate + 1.0Octadecenoate (N-C18:1) → 1.0Adenosine monophosphate + 1.0PE(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoglycerol (n-C12:0) + 1.0Adenosine triphosphate + 1.0Dodecanoate (N-C12:0) → 1.0Adenosine monophosphate + 1.0PG(12:0/12:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0) + 1.0Adenosine triphosphate + 1.0tetradecanoate (n-C14:0) → 1.0Adenosine monophosphate + 1.0PG(14:0/14:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1) + 1.0Adenosine triphosphate + 1.0Tetradecenoate (N-C14:1) → 1.0Adenosine monophosphate + 1.0PG(14:1(7Z)/14:1(7Z)) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0) + 1.0Adenosine triphosphate + 1.0Palmitic acid → 1.0Adenosine monophosphate + 1.0PG(16:0/16:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoglycerol (N-C18:0) + 1.0Adenosine triphosphate + 1.0Octadecanoate (N-C18:0) → 1.0Adenosine monophosphate + 1.0PG(18:0/18:0) + 1.0Pyrophosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Acyl-sn-glycero-3-phosphoglycerol (N-C18:1) + 1.0Adenosine triphosphate + 1.0Octadecenoate (N-C18:1) → 1.0Adenosine monophosphate + 1.0PG(18:1(11Z)/18:1(11Z)) + 1.0Pyrophosphate
ReactionCard
1.0Acyl-[acyl-carrier-protein]+1.0O-(2-acyl-sn-glycero-3-phospho)ethanolamine → 1.0[acyl-carrier-protein]+1.0O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine
1.0Acyl-[acyl-carrier-protein] + 1.0O-(2-acyl-sn-glycero-3-phospho)ethanolamine → 1.0[acyl-carrier-protein] + 1.0O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine
ReactionCard
1.0Thumb+1.0an acid+1.0[acyl-carrier-protein] → 1.0Thumb+1.0Thumb+1.0acyl-[acyl-carrier-protein]
1.0Adenosine triphosphate + 1.0an acid + 1.0[acyl-carrier-protein] → 1.0Adenosine monophosphate + 1.0Pyrophosphate + 1.0acyl-[acyl-carrier-protein]
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB211392-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0)MetaboCard
ECMDB211402-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)MetaboCard
ECMDB211412-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:1)MetaboCard
ECMDB211422-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)MetaboCard
ECMDB211432-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:1)MetaboCard
ECMDB211442-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)MetaboCard
ECMDB211452-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:1)MetaboCard
ECMDB211462-Acyl-sn-glycero-3-phosphoglycerol (n-C12:0)MetaboCard
ECMDB211472-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0)MetaboCard
ECMDB211482-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)MetaboCard
ECMDB211492-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)MetaboCard
ECMDB211502-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)MetaboCard
ECMDB211512-Acyl-sn-glycero-3-phosphoglycerol (N-C18:0)MetaboCard
ECMDB211522-Acyl-sn-glycero-3-phosphoglycerol (N-C18:1)MetaboCard
ECMDB00045Adenosine monophosphateMetaboCard
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB00482Caprylic acidMetaboCard
ECMDB21204Decanoate (N-C10:0)MetaboCard
ECMDB21209Dodecanoate (N-C12:0)MetaboCard
ECMDB21427Myristic acidMetaboCard
ECMDB21347Octadecanoate (N-C18:0)MetaboCard
ECMDB21348Octadecenoate (N-C18:1)MetaboCard
ECMDB00220Palmitic acidMetaboCard
ECMDB21442Palmitoleic acidMetaboCard
ECMDB23440PE(10:0(3-OH)/10:0(3-OH))MetaboCard
ECMDB23439PE(10:0(3-OH)/10:0)MetaboCard
ECMDB23442PE(10:0(3-OH)/12:0(3-OH))MetaboCard
ECMDB23441PE(10:0(3-OH)/12:0)MetaboCard
ECMDB23444PE(10:0(3-OH)/14:0(3-OH))MetaboCard
ECMDB23443PE(10:0(3-OH)/14:0)MetaboCard
ECMDB23445PE(10:0(3-OH)/15:0)MetaboCard
ECMDB23446PE(10:0(3-OH)/15:0cyclo)MetaboCard
ECMDB23447PE(10:0(3-OH)/16:0)MetaboCard
ECMDB23448PE(10:0(3-OH)/16:1(9Z))MetaboCard
ECMDB23449PE(10:0(3-OH)/17:0cycw7c)MetaboCard
ECMDB23450PE(10:0(3-OH)/18:1(9Z))MetaboCard
ECMDB23451PE(10:0(3-OH)/19:0cycv8c)MetaboCard
ECMDB23452PE(10:0(3-OH)/19:iso)MetaboCard
ECMDB23453PE(10:0/10:0(3-OH))MetaboCard
ECMDB21588PE(10:0/10:0)MetaboCard
ECMDB23454PE(10:0/12:0(3-OH))MetaboCard
ECMDB21589PE(10:0/12:0)MetaboCard
ECMDB23455PE(10:0/14:0(3-OH))MetaboCard
ECMDB21590PE(10:0/14:0)MetaboCard
ECMDB21591PE(10:0/15:0)MetaboCard
ECMDB21592PE(10:0/16:0)MetaboCard
ECMDB21593PE(10:0/16:1(9Z))MetaboCard
ECMDB21594PE(10:0/17:0cycw7c)MetaboCard
ECMDB21595PE(10:0/18:0)MetaboCard
ECMDB21596PE(10:0/18:1(11Z))MetaboCard
ECMDB21598PE(10:0/19:0cycw8c)MetaboCard
ECMDB21597PE(10:0/19:1(12Z))MetaboCard
ECMDB23456PE(10:0/19:iso)MetaboCard
ECMDB23458PE(12:0(3-OH)/10:0(3-OH))MetaboCard
ECMDB23457PE(12:0(3-OH)/10:0)MetaboCard
ECMDB23460PE(12:0(3-OH)/12:0(3-OH))MetaboCard
ECMDB23459PE(12:0(3-OH)/12:0)MetaboCard
ECMDB23462PE(12:0(3-OH)/14:0(3-OH))MetaboCard
ECMDB23461PE(12:0(3-OH)/14:0)MetaboCard
ECMDB23463PE(12:0(3-OH)/15:0)MetaboCard
ECMDB23464PE(12:0(3-OH)/15:0cyclo)MetaboCard
ECMDB23465PE(12:0(3-OH)/16:0)MetaboCard
ECMDB23466PE(12:0(3-OH)/16:1(9Z))MetaboCard
ECMDB23467PE(12:0(3-OH)/17:0cycw7c)MetaboCard
ECMDB23468PE(12:0(3-OH)/18:1(9Z))MetaboCard
ECMDB23469PE(12:0(3-OH)/19:0cycv8c)MetaboCard
ECMDB23470PE(12:0(3-OH)/19:iso)MetaboCard
ECMDB23471PE(12:0/10:0(3-OH))MetaboCard
ECMDB21599PE(12:0/10:0)MetaboCard
ECMDB23472PE(12:0/12:0(3-OH))MetaboCard
ECMDB21600PE(12:0/12:0)MetaboCard
ECMDB23473PE(12:0/14:0(3-OH))MetaboCard
ECMDB21601PE(12:0/14:0)MetaboCard
ECMDB21602PE(12:0/15:0)MetaboCard
ECMDB21603PE(12:0/16:0)MetaboCard
ECMDB21604PE(12:0/16:1(9Z))MetaboCard
ECMDB21605PE(12:0/17:0cycw7c)MetaboCard
ECMDB21606PE(12:0/18:0)MetaboCard
ECMDB21607PE(12:0/18:1(11Z))MetaboCard
ECMDB21609PE(12:0/19:0cycw8c)MetaboCard
ECMDB21608PE(12:0/19:1(12Z))MetaboCard
ECMDB23474PE(12:0/19:iso)MetaboCard
ECMDB23476PE(14:0(3-OH)/10:0(3-OH))MetaboCard
ECMDB23475PE(14:0(3-OH)/10:0)MetaboCard
ECMDB23478PE(14:0(3-OH)/12:0(3-OH))MetaboCard
ECMDB23477PE(14:0(3-OH)/12:0)MetaboCard
ECMDB23480PE(14:0(3-OH)/14:0(3-OH))MetaboCard
ECMDB23479PE(14:0(3-OH)/14:0)MetaboCard
ECMDB23481PE(14:0(3-OH)/15:0)MetaboCard
ECMDB23482PE(14:0(3-OH)/15:0cyclo)MetaboCard
ECMDB23483PE(14:0(3-OH)/16:0)MetaboCard
ECMDB23484PE(14:0(3-OH)/16:1(9Z))MetaboCard
ECMDB23485PE(14:0(3-OH)/17:0cycw7c)MetaboCard
ECMDB23486PE(14:0(3-OH)/18:1(9Z))MetaboCard
ECMDB23487PE(14:0(3-OH)/19:0cycv8c)MetaboCard
ECMDB23488PE(14:0(3-OH)/19:iso)MetaboCard
ECMDB23489PE(14:0/10:0(3-OH))MetaboCard
ECMDB21610PE(14:0/10:0)MetaboCard
ECMDB23490PE(14:0/12:0(3-OH))MetaboCard
ECMDB21611PE(14:0/12:0)MetaboCard
ECMDB23491PE(14:0/14:0(3-OH))MetaboCard
ECMDB08821PE(14:0/14:0)MetaboCard
ECMDB08824PE(14:0/16:0)MetaboCard
ECMDB08825PE(14:0/16:1(9Z))MetaboCard
ECMDB21024PE(14:0/17:0)MetaboCard
ECMDB21612PE(14:0/17:0cycw7c)MetaboCard
ECMDB08827PE(14:0/18:1(11Z))MetaboCard
ECMDB21025PE(14:0/19:0)MetaboCard
ECMDB23492PE(14:0/19:iso)MetaboCard
ECMDB23493PE(15:0/10:0(3-OH))MetaboCard
ECMDB21613PE(15:0/10:0)MetaboCard
ECMDB23494PE(15:0/12:0(3-OH))MetaboCard
ECMDB21614PE(15:0/12:0)MetaboCard
ECMDB23495PE(15:0/14:0(3-OH))MetaboCard
ECMDB21615PE(15:0/17:0cycw7c)MetaboCard
ECMDB23496PE(15:0/19:iso)MetaboCard
ECMDB23497PE(15:0cyclo/10:0(3-OH))MetaboCard
ECMDB23498PE(15:0cyclo/12:0(3-OH))MetaboCard
ECMDB23499PE(15:0cyclo/14:0(3-OH))MetaboCard
ECMDB23500PE(15:0cyclo/19:iso)MetaboCard
ECMDB23501PE(16:0/10:0(3-OH))MetaboCard
ECMDB21616PE(16:0/10:0)MetaboCard
ECMDB23502PE(16:0/12:0(3-OH))MetaboCard
ECMDB21617PE(16:0/12:0)MetaboCard
ECMDB23503PE(16:0/14:0(3-OH))MetaboCard
ECMDB08920PE(16:0/14:0)MetaboCard
ECMDB08923PE(16:0/16:0)MetaboCard
ECMDB08924PE(16:0/16:1(9Z))MetaboCard
ECMDB21026PE(16:0/17:0)MetaboCard
ECMDB21618PE(16:0/17:0cycw7c)MetaboCard
ECMDB08926PE(16:0/18:1(11Z))MetaboCard
ECMDB21027PE(16:0/19:0)MetaboCard
ECMDB21619PE(16:0/19:0cycw8c)MetaboCard
ECMDB23504PE(16:0/19:iso)MetaboCard
ECMDB23505PE(16:1(9Z)/10:0(3-OH))MetaboCard
ECMDB21620PE(16:1(9Z)/10:0)MetaboCard
ECMDB23506PE(16:1(9Z)/12:0(3-OH))MetaboCard
ECMDB21621PE(16:1(9Z)/12:0)MetaboCard
ECMDB23507PE(16:1(9Z)/14:0(3-OH))MetaboCard
ECMDB08953PE(16:1(9Z)/14:0)MetaboCard
ECMDB08956PE(16:1(9Z)/16:0)MetaboCard
ECMDB08957PE(16:1(9Z)/16:1(9Z))MetaboCard
ECMDB21065PE(16:1(9Z)/17:0)MetaboCard
ECMDB08959PE(16:1(9Z)/18:1(11Z))MetaboCard
ECMDB21066PE(16:1(9Z)/19:0)MetaboCard
ECMDB23508PE(16:1(9Z)/19:iso)MetaboCard
ECMDB21028PE(17:0/14:0)MetaboCard
ECMDB21014PE(17:0/16:0)MetaboCard
ECMDB21060PE(17:0/16:1(9Z))MetaboCard
ECMDB21015PE(17:0/17:0)MetaboCard
ECMDB21062PE(17:0/18:1(11Z))MetaboCard
ECMDB21016PE(17:0/19:0)MetaboCard
ECMDB23509PE(17:0cycw7c/10:0(3-OH))MetaboCard
ECMDB21622PE(17:0cycw7c/10:0)MetaboCard
ECMDB23510PE(17:0cycw7c/12:0(3-OH))MetaboCard
ECMDB21623PE(17:0cycw7c/12:0)MetaboCard
ECMDB23511PE(17:0cycw7c/14:0(3-OH))MetaboCard
ECMDB21633PE(17:0cycw7c/17:0cycw7c)MetaboCard
ECMDB23512PE(17:0cycw7c/19:iso)MetaboCard
ECMDB21624PE(18:0/10:0)MetaboCard
ECMDB21625PE(18:0/12:0)MetaboCard
ECMDB21626PE(18:0/17:0cycw7c)MetaboCard
ECMDB21627PE(18:1(11Z)/10:0)MetaboCard
ECMDB21628PE(18:1(11Z)/12:0)MetaboCard
ECMDB09019PE(18:1(11Z)/14:0)MetaboCard
ECMDB09022PE(18:1(11Z)/16:0)MetaboCard
ECMDB09023PE(18:1(11Z)/16:1(9Z))MetaboCard
ECMDB21058PE(18:1(11Z)/17:0)MetaboCard
ECMDB09025PE(18:1(11Z)/18:1(11Z))MetaboCard
ECMDB21059PE(18:1(11Z)/19:0)MetaboCard
ECMDB23513PE(18:1(9Z)/10:0(3-OH))MetaboCard
ECMDB23514PE(18:1(9Z)/12:0(3-OH))MetaboCard
ECMDB23515PE(18:1(9Z)/14:0(3-OH))MetaboCard
ECMDB23516PE(18:1(9Z)/19:iso)MetaboCard
ECMDB21017PE(19:0/14:0)MetaboCard
ECMDB21018PE(19:0/16:0)MetaboCard
ECMDB21064PE(19:0/16:1(9Z))MetaboCard
ECMDB21019PE(19:0/17:0)MetaboCard
ECMDB21061PE(19:0/18:1(11Z))MetaboCard
ECMDB21020PE(19:0/19:0)MetaboCard
ECMDB23517PE(19:0cycv8c/10:0(3-OH))MetaboCard
ECMDB23518PE(19:0cycv8c/12:0(3-OH))MetaboCard
ECMDB23519PE(19:0cycv8c/14:0(3-OH))MetaboCard
ECMDB23520PE(19:0cycv8c/19:iso)MetaboCard
ECMDB21631PE(19:0cycw8c/10:0)MetaboCard
ECMDB21632PE(19:0cycw8c/12:0)MetaboCard
ECMDB21634PE(19:0cycw8c/17:0cycw7c)MetaboCard
ECMDB21629PE(19:1(12Z)/10:0)MetaboCard
ECMDB21630PE(19:1(12Z)/12:0)MetaboCard
ECMDB23522PE(19:iso/10:0(3-OH))MetaboCard
ECMDB23521PE(19:iso/10:0)MetaboCard
ECMDB23524PE(19:iso/12:0(3-OH))MetaboCard
ECMDB23523PE(19:iso/12:0)MetaboCard
ECMDB23526PE(19:iso/14:0(3-OH))MetaboCard
ECMDB23525PE(19:iso/14:0)MetaboCard
ECMDB23527PE(19:iso/15:0)MetaboCard
ECMDB23528PE(19:iso/15:0cyclo)MetaboCard
ECMDB23529PE(19:iso/16:0)MetaboCard
ECMDB23530PE(19:iso/16:1(9Z))MetaboCard
ECMDB23531PE(19:iso/17:0cycw7c)MetaboCard
ECMDB23532PE(19:iso/18:1(9Z))MetaboCard
ECMDB23533PE(19:iso/19:0cycv8c)MetaboCard
ECMDB23534PE(19:iso/19:iso)MetaboCard
ECMDB21265PG(12:0/12:0)MetaboCard
ECMDB21013PG(14:0/14:0)MetaboCard
ECMDB21266PG(14:1(7Z)/14:1(7Z))MetaboCard
ECMDB10570PG(16:0/16:0)MetaboCard
ECMDB10586PG(16:1(9Z)/16:1(9Z))MetaboCard
ECMDB21267PG(18:0/18:0)MetaboCard
ECMDB10618PG(18:1(11Z)/18:1(11Z))MetaboCard
ECMDB04142PyrophosphateMetaboCard
ECMDB21428Stearic acidMetaboCard
ECMDB21361tetradecanoate (n-C14:0)MetaboCard
ECMDB21362Tetradecenoate (N-C14:1)MetaboCard
ECMDB21443Vaccenic acidMetaboCard
GO Classification:
Function
acyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
Process
metabolic process
Gene Properties
Blattner:b2836
Gene OrientationCounterclockwise
Centisome Percentage:64.05
Left Sequence End2971877
Right Sequence End2974036
Gene Sequence:
>2160 bp
ATGCTTTTTAGCTTTTTTCGAAATTTGTGCCGTGTTTTGTATCGCGTTCGCGTTACGGGT
GACACCCAGGCACTGAAGGGCGAGCGCGTTCTAATTACGCCTAATCACGTCTCTTTTATT
GATGGCATTTTGCTTGGACTGTTTTTACCTGTGCGTCCAGTGTTTGCCGTTTACACCTCA
ATAAGCCAACAGTGGTATATGCGTTGGCTGAAATCATTTATCGACTTTGTTCCTCTCGAC
CCGACGCAACCTATGGCTATTAAACATCTGGTACGTCTGGTGGAACAGGGCCGACCAGTG
GTGATTTTCCCTGAAGGACGCATCACCACGACAGGCTCGCTGATGAAAATCTACGATGGC
GCGGGTTTTGTCGCGGCGAAGTCTGGTGCAACGGTTATTCCTGTGCGTATTGAAGGGGCG
GAACTTACGCACTTCAGCCGCCTGAAAGGTCTGGTTAAACGTCGCTTGTTCCCGCAAATT
ACTCTGCATATTTTGCCACCAACGCAGGTGGCGATGCCGGATGCGCCGCGTGCCCGTGAC
CGTCGCAAAATCGCTGGCGAAATGCTGCATCAAATAATGATGGAAGCGCGAATGGCGGTG
CGCCCGCGTGAAACGCTGTACGAATCTTTACTGAGTGCAATGTACCGCTTCGGAGCCGGG
AAGAAATGTGTCGAAGACGTCAACTTTACCCCAGACTCCTATCGCAAATTGCTTACGAAA
ACGCTGTTTGTTGGACGCATCCTTGAAAAATACAGTGTTGAAGGCGAACGCATCGGCTTA
ATGCTGCCCAATGCAGGCATCAGTGCGGCAGTGATTTTTGGGGCCATCGCCCGTCGCCGC
ATGCCCGCAATGATGAACTACACTGCCGGGGTAAAAGGGCTGACCAGTGCTATTACGGCG
GCTGAAATCAAAACCATCTTCACTTCCCGCCAGTTTCTCGATAAAGGCAAACTCTGGCAT
CTGCCGGAGCAACTTACTCAGGTGCGCTGGGTCTATCTGGAAGATTTAAAAGCAGATGTC
ACCACTGCCGACAAAGTATGGATCTTCGCTCATTTGCTGATGCCGCGTCTGGCACAGGTT
AAACAGCAGCCGGAAGAAGAGGCGCTGATCCTTTTTACCTCCGGTTCTGAAGGCCATCCG
AAAGGCGTCGTCCATAGCCATAAAAGCATTCTGGCGAATGTCGAGCAGATTAAAACGATT
GCCGACTTCACCACCAACGATCGCTTTATGTCGGCGTTACCGCTGTTTCACTCCTTTGGG
CTGACGGTAGGCCTGTTTACGCCACTGCTTACAGGTGCAGAAGTGTTCCTTTATCCAAGC
CCGCTGCATTACCGCATTGTGCCGGAGTTGGTGTATGACCGCAGTTGCACCGTGTTGTTC
GGCACCTCGACTTTCCTCGGTCACTACGCGCGTTTCGCCAACCCGTATGACTTCTATCGT
CTACGCTATGTGGTGGCAGGCGCAGAAAAATTACAAGAAAGTACCAAACAGCTTTGGCAG
GATAAATTTGGCCTGCGCATCCTTGAAGGCTACGGCGTGACCGAATGCGCGCCTGTCGTT
TCTATCAACGTACCGATGGCGGCGAAACCCGGTACGGTAGGGCGTATTCTACCAGGAATG
GATGCGCGCCTGTTGTCGGTCCCTGGTATCGAAGAGGGCGGACGCCTGCAACTGAAAGGG
CCGAACATAATGAACGGCTATCTGCGGGTGGAGAAGCCAGGTGTACTGGAAGTGCCCACC
GCCGAGAATGTTCGCGGCGAAATGGAGCGCGGCTGGTATGACACTGGCGATATTGTGCGT
TTTGACGAGCAGGGCTTTGTGCAGATTCAGGGCCGCGCAAAACGCTTTGCCAAAATTGCA
GGCGAAATGGTGTCGCTGGAAATGGTGGAACAACTGGCACTTGGTGTTTCGCCAGATAAA
GTCCATGCCACTGCGATTAAGAGCGATGCCAGCAAAGGCGAGGCACTGGTGCTTTTCACC
ACAGATAACGAACTGACGCGCGATAAGTTGCAACAGTATGCCCGCGAGCACGGCGTGCCG
GAGCTTGCTGTACCGCGCGATATTCGCTATCTGAAACAGATGCCATTACTTGGCAGCGGC
AAACCTGACTTTGTCACGTTGAAAAGCTGGGTAGACGAAGCGGAACAACACGATGAGTGA
Protein Properties
Pfam Domain Function:
Protein Residues:719
Protein Molecular Weight:80699
Protein Theoretical pI:10
Signaling Regions:
  • None
Transmembrane Regions:
  • 258-277
  • 409-433
Protein Sequence:
>Bifunctional protein aas
MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTS
ISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDG
AGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQITLHILPPTQVAMPDAPRARD
RRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTK
TLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRMPAMMNYTAGVKGLTSAITA
AEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQV
KQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTTNDRFMSALPLFHSFG
LTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYR
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGM
DARLLSVPGIEEGGRLQLKGPNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVR
FDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFT
TDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE
References
External Links:
ResourceLink
Uniprot ID:P31119
Uniprot Name:AAS_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85675652
Ecogene ID:EG11679
Ecocyc:EG11679
ColiBase:b2836
Kegg Gene:b2836
EchoBASE ID:EB1630
CCDB:AAS_ECOLI
BacMap:16130740
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Heath, R. J., Rock, C. O. (1998). "A conserved histidine is essential for glycerolipid acyltransferase catalysis." J Bacteriol 180:1425-1430. Pubmed: 9515909
  • Hsu, L., Jackowski, S., Rock, C. O. (1991). "Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity." J Biol Chem 266:13783-13788. Pubmed: 1649829
  • Jackowski, S., Jackson, P. D., Rock, C. O. (1994). "Sequence and function of the aas gene in Escherichia coli." J Biol Chem 269:2921-2928. Pubmed: 8300626
  • Lenski, R. E., Winkworth, C. L., Riley, M. A. (2003). "Rates of DNA sequence evolution in experimental populations of Escherichia coli during 20,000 generations." J Mol Evol 56:498-508. Pubmed: 12664169