FMN reductase (P80644)

Identification
Name:FMN reductase
Synonyms:
  • Sulfate starvation-induced protein 4
  • SSI4
Gene Name:ssuE
Enzyme Class:
Biological Properties
General Function:Involved in FMN reductase activity
Specific Function:Catalyzes an NAD(P)H-dependent reduction of FMN, but is also able to reduce FAD or riboflavin
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0Flavin Mononucleotide + 1.0Hydrogen ion + 1.0NADH → 1.0FMNH + 1.0NAD
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Flavin Mononucleotide + 1.0Hydrogen ion + 1.0NADPH ↔ 1.0FMNH + 1.0NADP
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0FMNH + 1.0NADP ↔ 1.0Flavin Mononucleotide + 1.0NADPH + 1.0Hydrogen ion
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Flavin Mononucleotide + 1.0Hydrogen ion + 1.0NADPH ↔ 1.0FMNH + 1.0NADP
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0FMNH(2) + 1.0NADP → 1.0Flavin Mononucleotide + 1.0NADPH
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21646AldehydeMetaboCard
ECMDB23762AlkanesulfonateMetaboCard
ECMDB01520Flavin MononucleotideMetaboCard
ECMDB01142FMNHMetaboCard
ECMDB23187FMNH(2)MetaboCard
ECMDB01426FormaldehydeMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB21344MethanesulfonateMetaboCard
ECMDB00902NADMetaboCard
ECMDB01487NADHMetaboCard
ECMDB00217NADPMetaboCard
ECMDB04111NADPHMetaboCard
ECMDB04124OxygenMetaboCard
ECMDB00240SulfiteMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b0937
Gene OrientationCounterclockwise
Centisome Percentage:21.47
Left Sequence End996160
Right Sequence End996735
Gene Sequence:
>576 bp
ATGCGTGTCATCACCCTGGCGGGTAGTCCTCGCTTTCCTTCTCGCTCCAGCTCCTTGCTG
GAATATGCGCGGGAAAAACTAAATGGCCTGGATGTAGAGGTTTATCACTGGAATCTGCAA
AACTTCGCCCCGGAAGATCTACTTTATGCTCGTTTCGATAGTCCGGCACTCAAGACCTTC
ACCGAACAGCTGCAACAGGCCGATGGGCTGATTGTCGCCACGCCTGTGTATAAAGCCGCC
TATTCCGGTGCGTTGAAAACCCTGCTCGACCTGCTGCCAGAACGCGCTTTGCAAGGCAAA
GTGGTGCTACCGCTGGCGACGGGCGGTACCGTGGCCCATCTGCTGGCGGTCGATTATGCC
CTTAAACCAGTTTTAAGCGCACTGAAAGCTCAGGAGATCCTGCACGGCGTGTTTGCCGAT
GACTCACAAGTAATTGATTACCATCACAGACCCCAGTTCACGCCAAATCTGCAAACCCGT
CTTGATACCGCGCTAGAAACTTTCTGGCAGGCATTGCACCGCCGCGATGTTCAGGTTCCT
GACCTTCTGTCTCTGCGAGGTAATGCCCATGCGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:191
Protein Molecular Weight:21253
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>FMN reductase
MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAPEDLLYARFDSPALKTF
TEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYA
LKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTRLDTALETFWQALHRRDVQVP
DLLSLRGNAHA
References
External Links:
ResourceLink
Uniprot ID:P80644
Uniprot Name:SSUE_ECOLI
GenBank Gene ID:AJ237695
Genebank Protein ID:4583566
Ecogene ID:EG13708
Ecocyc:EG13708
ColiBase:b0937
Kegg Gene:b0937
EchoBASE ID:EB3472
CCDB:SSUE_ECOLI
BacMap:16128904
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Eichhorn, E., van der Ploeg, J. R., Leisinger, T. (1999). "Characterization of a two-component alkanesulfonate monooxygenase from Escherichia coli." J Biol Chem 274:26639-26646. Pubmed: 10480865
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • Quadroni, M., Staudenmann, W., Kertesz, M., James, P. (1996). "Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli." Eur J Biochem 239:773-781. Pubmed: 8774726
  • van Der Ploeg, J. R., Iwanicka-Nowicka, R., Bykowski, T., Hryniewicz, M. M., Leisinger, T. (1999). "The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl." J Biol Chem 274:29358-29365. Pubmed: 10506196