Biopolymer transport protein exbD (P0ABV2)

Identification
Name:Biopolymer transport protein exbD
Synonyms:Not Available
Gene Name:exbD
Enzyme Class:Not Available
Biological Properties
General Function:Involved in transporter activity
Specific Function:Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates
Cellular Location:Cell inner membrane; Single-pass type II membrane protein
SMPDB Pathways:
  • Biosynthesis of siderophore group nonribosomal peptides PW000760
  • adenosylcobalamin salvage from cobinamide PW001884
KEGG Pathways:
  • Biosynthesis of siderophore group nonribosomal peptides ec01053
Transports:
Transport References:
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
Metabolites:
ECMDB IDNameView
ECMDB02086AdenosylcobalaminMetaboCard
ECMDB04040Cob(I)alaminMetaboCard
ECMDB06902CobinamideMetaboCard
ECMDB21213Fe(III)dicitrateMetaboCard
ECMDB21331ferric 2,3-dihydroxybenzoylserineMetaboCard
ECMDB20516Ferric coprogenMetaboCard
ECMDB21372Ferric enterobactinMetaboCard
ECMDB21218FerrichromeMetaboCard
ECMDB21333FerroxamineMetaboCard
ECMDB21225Hydrogen ionMetaboCard
GO Classification:
Component
cell part
membrane
Function
transporter activity
Process
establishment of localization
transport
Gene Properties
Blattner:b3005
Gene OrientationCounterclockwise
Centisome Percentage:67.87
Left Sequence End3148840
Right Sequence End3149265
Gene Sequence:
>426 bp
GTGGCCACTCTCTGCCATGTGTTCGGGGTTCATCGCAGCAGCTACAAATACTGGAAAAAC
CGTCCTGAAAAGCCAGACGGCAGACGGGCTGTATTACGCAGTCAGGTACTTGAACTGCAT
GGCATCAGCCACGGCTCTGCCGGAGCAAGAAGCATCGCCACAATGGCAACCCAGAGAGGA
TACCAGATGGGGCGCTGGCTTGCTGGCAGACTCATGAAAGAGCTGGGGCTGGTCAGTTGC
CAGCAGCCGACTCACCGGTATAAGCGTGGCGGTCATGAGCACGTTGCTATCCCGAATCAT
CTTGAGCGACAGTTCGCCGTAACGGAACCAAATCAGGTGTGGTGCGGTGATGTGACCTAT
AGTGTGCCCGGAGTTCAGGGCGGGCATGGATGCTTAAATGAACCGCGAGTCTGTCTGGAA
TATTGA
Protein Properties
Pfam Domain Function:
Protein Residues:141
Protein Molecular Weight:15527
Protein Theoretical pI:4
Signaling Regions:
  • None
Transmembrane Regions:
  • 23-43
Protein Sequence:
>Biopolymer transport protein exbD
MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVDVKVNLPASTSTPQPRP
EKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTIFFRADKTVDYETLMKVMD
TLHQAGYLKIGLVGEETAKAK
References
External Links:
ResourceLink
Uniprot ID:P0ABV2
Uniprot Name:EXBD_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674401
Ecogene ID:EG10272
Ecocyc:EG10272
ColiBase:b3005
Kegg Gene:b3005
EchoBASE ID:EB0268
CCDB:EXBD_ECOLI
BacMap:16130903
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Eick-Helmerich, K., Braun, V. (1989). "Import of biopolymers into Escherichia coli: nucleotide sequences of the exbB and exbD genes are homologous to those of the tolQ and tolR genes, respectively." J Bacteriol 171:5117-5126. Pubmed: 2670903
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Kampfenkel, K., Braun, V. (1992). "Membrane topology of the Escherichia coli ExbD protein." J Bacteriol 174:5485-5487. Pubmed: 1644779