Trimethylamine N-Oxide (ECMDB04161) (M2MDB000643)

General function:

Involved in electron carrier activity

Specific function:

Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds

Gene Name:

ynfG

Uniprot ID:

P0AAJ1

Molecular weight:

22752

General function:

Involved in dimethyl sulfoxide reductase activity

Specific function:

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. Allows E.coli to grow anaerobically on Me(2)SO as respiratory oxidant

Gene Name:

dmsA

Uniprot ID:

P18775

Molecular weight:

90398

Reactions

General function:

Involved in electron carrier activity

Specific function:

Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds

Gene Name:

dmsB

Uniprot ID:

P18776

Molecular weight:

22869

General function:

Involved in dimethyl sulfoxide reductase activity

Specific function:

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds

Gene Name:

ynfE

Uniprot ID:

P77374

Molecular weight:

89779

General function:

Involved in dimethyl sulfoxide reductase activity

Specific function:

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds

Gene Name:

ynfF

Uniprot ID:

P77783

Molecular weight:

89986

General function:

Involved in oxidoreductase activity

Specific function:

Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. Can also reduce other N- and S-oxide compounds such as 4-methylmorpholine-N-oxide and biotin sulfoxide (BSO), but with a lower catalytic efficiency

Gene Name:

torZ

Uniprot ID:

P46923

Molecular weight:

88964

Reactions

General function:

Involved in iron ion binding

Specific function:

Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase torZ. Required for electron transfer to the torZ terminal enzyme

Gene Name:

torY

Uniprot ID:

P52005

Molecular weight:

40286

General function:

Involved in anaerobic electron transport chain

Specific function:

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it

Gene Name:

dmsC

Uniprot ID:

P18777

Molecular weight:

30826

General function:

Involved in oxidoreductase activity

Specific function:

Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions

Gene Name:

torA

Uniprot ID:

P33225

Molecular weight:

94455

Reactions

General function:

Involved in iron ion binding

Specific function:

Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase torA. Acts by transferring electrons from the membranous menaquinones to torA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal domain of torC, then from the N-terminus to the C-terminus, and finally to torA. TorC apocytochrome negatively autoregulates the torCAD operon probably by inhibiting the torS kinase activity

Gene Name:

torC

Uniprot ID:

P33226

Molecular weight:

43606

General function:

Involved in anaerobic electron transport chain

Specific function:

Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. The C subunit anchors the other two subunits to the membrane and stabilize the catalytic subunits

Gene Name:

ynfH

Uniprot ID:

P76173

Molecular weight:

30523