Xanthine dehydrogenase iron-sulfur-binding subunit (Q46801)

Identification
Name:Xanthine dehydrogenase iron-sulfur-binding subunit
Synonyms:Not Available
Gene Name:xdhC
Enzyme Class:Not Available
Biological Properties
General Function:Involved in oxidoreductase activity
Specific Function:Iron-sulfur subunit of the xanthine dehydrogenase complex
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Water + 1.0Hypoxanthine + 1.0NAD → 1.0Hydrogen ion + 1.0NADH + 1.0Xanthine
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Water + 1.0NAD + 1.0Xanthine ↔ 1.0Hydrogen ion + 1.0NADH + 1.0Uric acid
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Hypoxanthine + 1.0NAD + 1.0Water ↔ 1.0Xanthine + 1.0NADH + 1.0Hydrogen ion
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Water + 1.0Hypoxanthine + 1.0NAD → 1.0Hydrogen ion + 1.0NADH + 1.0Xanthine
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Water + 1.0NAD + 1.0Xanthine ↔ 1.0Hydrogen ion + 1.0NADH + 1.0Uric acid
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Xanthine + 1.0NAD + 1.0Water → 1.0Uric acid + 1.0NADH + 1.0Hydrogen ion
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21225Hydrogen ionMetaboCard
ECMDB00157HypoxanthineMetaboCard
ECMDB00902NADMetaboCard
ECMDB01487NADHMetaboCard
ECMDB00289Uric acidMetaboCard
ECMDB00494WaterMetaboCard
ECMDB00292XanthineMetaboCard
GO Classification:
Function
binding
catalytic activity
cation binding
electron carrier activity
ion binding
iron-sulfur cluster binding
metal cluster binding
metal ion binding
oxidoreductase activity
Process
metabolic process
oxidation reduction
Gene Properties
Blattner:b2868
Gene OrientationClockwise
Centisome Percentage:64.69
Left Sequence End3001511
Right Sequence End3001990
Gene Sequence:
>480 bp
ATGATCAGTCTGATTGCGGCGTTAGCGGTAGATCGCGTTATCGGCATGGAAAACGCCATG
CCGTGGAACCTGCCTGCCGATCTCGCCTGGTTTAAACGCAACACCTTAAATAAACCCGTG
ATTATGGGCCGCCATACCTGGGAATCAATCGGTCGTCCGTTGCCAGGACGCAAAAATATT
ATCCTCAGCAGTCAACCGGGTACGGACGATCGCGTAACGTGGGTGAAGTCGGTGGATGAA
GCCATCGCGGCGTGTGGTGACGTACCAGAAATCATGGTGATTGGCGGCGGTCGCGTTTAT
GAACAGTTCTTGCCAAAAGCGCAAAAACTGTATCTGACGCATATCGACGCAGAAGTGGAA
GGCGACACCCATTTCCCGGATTACGAGCCGGATGACTGGGAATCGGTATTCAGCGAATTC
CACGATGCTGATGCGCAGAACTCTCACAGCTATTGCTTTGAGATTCTGGAGCGGCGGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:159
Protein Molecular Weight:16922
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Xanthine dehydrogenase iron-sulfur-binding subunit
MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTA
IDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAK
PREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
References
External Links:
ResourceLink
Uniprot ID:Q46801
Uniprot Name:XDHC_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:21321929
Ecogene ID:EG13051
Ecocyc:EG13051
ColiBase:b2868
Kegg Gene:b2868
EchoBASE ID:EB2863
CCDB:XDHC_ECOLI
BacMap:16130770
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Xi, H., Schneider, B. L., Reitzer, L. (2000). "Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage." J Bacteriol 182:5332-5341. Pubmed: 10986234