Ethanolamine utilization cobalamin adenosyltransferase (P65643)

Identification
Name:Ethanolamine utilization cobalamin adenosyltransferase
Synonyms:Not Available
Gene Name:eutT
Enzyme Class:
Biological Properties
General Function:Involved in ATP binding
Specific Function:Converts CNB12 to ADOB12
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Cob(I)alamin + 1.0Hydrogen ion ↔ 1.0Adenosylcobalamin + 1.0Triphosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Cobinamide + 1.0Hydrogen ion ↔ 1.0Adenosyl cobinamide + 1.0Triphosphate
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Cob(I)alamin ↔ 1.0Triphosphate + 1.0Adenosylcobalamin
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Cob(I)yrinate a,c diamide + 1.0Cobinamide ↔ 1.0Triphosphate + 1.0Adenosyl cobyrinate a,c diamide + 1.0Adenosyl cobinamide
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Cob(I)alamin + 1.0Hydrogen ion ↔ 1.0Adenosylcobalamin + 1.0Triphosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB06903Adenosyl cobinamideMetaboCard
ECMDB23132Adenosylcob(III)yrinic acid a,c-diamideMetaboCard
ECMDB02086AdenosylcobalaminMetaboCard
ECMDB04040Cob(I)alaminMetaboCard
ECMDB01083Cob(I)yrinate a,c diamideMetaboCard
ECMDB06902CobinamideMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB03379TriphosphateMetaboCard
GO Classification:
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
binding
catalytic activity
cob(I)yrinic acid a,c-diamide adenosyltransferase activity
nucleoside binding
purine nucleoside binding
transferase activity
transferase activity, transferring alkyl or aryl (other than methyl) groups
Process
alcohol metabolic process
cobalamin biosynthetic process
ethanolamine and derivative metabolic process
ethanolamine metabolic process
metabolic process
nitrogen compound metabolic process
porphyrin biosynthetic process
porphyrin metabolic process
small molecule metabolic process
tetrapyrrole metabolic process
Gene Properties
Blattner:b2459
Gene OrientationCounterclockwise
Centisome Percentage:55.42
Left Sequence End2571524
Right Sequence End2572327
Gene Sequence:
>804 bp
ATGGCTATCCCTGCATTTGGTTTAGGTACTTTCCGTCTGAAAGACGACGTTGTTATTTCA
TCTGTGATAACGGCGCTTGAACTTGGTTATCGCGCAATTGATACCGCACAAATCTATGAT
AACGAAGCCGCAGTAGGTCAGGCGATTGCAGAAAGTGGCGTGCCACGTCATGAACTCTAC
ATCACCACTAAAATCTGGATTGAAAATCTCAGCAAAGACAAATTGATCCCAAGTCTGAAA
GAGAGCCTGCAAAAATTGCGTACCGATTATGTTGATCTGACGCTAATCCACTGGCCGTCA
CCAAACGATGAAGTCTCTGTTGAAGAGTTTATGCAGGCGCTGCTGGAAGCCAAAAAACAA
GGGCTGACGCGTGAGATCGGTATTTCCAACTTCACGATCCCGTTGATGGAAAAAGCGATT
GCTGCTGTTGGTGCTGAAAACATCGCTACTAACCAGATTGAACTCTCTCCTTATCTGCAA
AACCGTAAAGTGGTTGCCTGGGCTAAACAGCACGGCATCCATATTACTTCCTATATGACG
CTGGCGTATGGTAAGGCCCTGAAAGATGAGGTTATTGCTCGTATCGCAGCTAAACACAAT
GCGACTCCGGCACAAGTGATTCTGGCGTGGGCTATGGGGGAAGGTTACTCAGTAATTCCT
TCTTCTACTAAACGTAAAAACCTGGAAAGTAATCTTAAGGCACAAAATTTACAGCTTGAT
GCCGAAGATAAAAAAGCGATCGCCGCACTGGATTGCAACGACCGCCTGGTTAGCCCGGAA
GGTCTGGCTCCTGAATGGGATTAA
Protein Properties
Pfam Domain Function:
Protein Residues:267
Protein Molecular Weight:30171
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Ethanolamine utilization cobalamin adenosyltransferase
MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLRIKFIDEQGRLFVDDEQ
QQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKMVAKSDPRLGFRAVLDSTI
ALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGCQAIVGLSDEDLHRLSHQPLR
YLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVFITRSFEVLRPDILQALNRLSST
VYVMMILSVTKQPLTVKQIQQRLGETQ
References
External Links:
ResourceLink
Uniprot ID:P65643
Uniprot Name:EUTT_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674382
Ecogene ID:EG14189
Ecocyc:EG14189
ColiBase:b2459
Kegg Gene:b2459
EchoBASE ID:EB3941
CCDB:EUTT_ECOLI
BacMap:16130384
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553