Ribulokinase (P08204)

Identification
Name:Ribulokinase
Synonyms:Not Available
Gene Name:araB
Enzyme Class:
Biological Properties
General Function:Involved in phosphotransferase activity, alcohol group as acceptor
Specific Function:ATP + L(or D)-ribulose = ADP + L(or D)- ribulose 5-phosphate
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0D-Xylulose ↔ 1.0ADP + 1.0Hydrogen ion + 1.0Xylulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Threo-2-pentulose ↔ 1.0ADP + 1.0Hydrogen ion + 1.0L-Xylulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Ribulose → 1.0ADP + 1.0Hydrogen ion + 1.0L-Ribulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0D-Ribulose 5-phosphate
1.0Adenosine triphosphate + 1.0D-Ribulose ↔ 1.0ADP + 1.0D-Ribulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Ribulose ↔ 1.0ADP + 1.0L-Ribulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Ribulose + 1.0D-Ribulose ↔ 1.0ADP + 1.0L-Ribulose 5-phosphate + 1.0D-Ribulose 5-phosphate
ReactionCard
SMPDB Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0L-Ribulose + 1.0Adenosine triphosphate → 1.0 L-ribulose 5-phosphate + 1.0ADP + 1.0Hydrogen ion
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0D-Xylulose ↔ 1.0ADP + 1.0Hydrogen ion + 1.0Xylulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Ribulose → 1.0ADP + 1.0Hydrogen ion + 1.0L-Ribulose 5-phosphate
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Ribulose ↔ 1.0ADP + 1.0L-Ribulose 5-phosphate
ReactionCard
Complex Reactions:
1.0Thumb+1.0L(or D)-ribulose → 1.0Thumb+1.0L(or D)-ribulose 5-phosphate
1.0Adenosine triphosphate + 1.0L(or D)-ribulose → 1.0ADP + 1.0L(or D)-ribulose 5-phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB24194 L-ribulose 5-phosphateMetaboCard
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB00621D-RibuloseMetaboCard
ECMDB04148D-Ribulose 5-phosphateMetaboCard
ECMDB00654D-XyluloseMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB04149L-RibuloseMetaboCard
ECMDB20167L-Ribulose 5-phosphateMetaboCard
ECMDB00751L-Threo-2-pentuloseMetaboCard
ECMDB20169L-Xylulose 5-phosphateMetaboCard
ECMDB04178Xylulose 5-phosphateMetaboCard
GO Classification:
Function
catalytic activity
phosphotransferase activity, alcohol group as acceptor
ribulokinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
alcohol metabolic process
arabinose catabolic process
carbohydrate metabolic process
L-arabinose catabolic process
metabolic process
monosaccharide metabolic process
pentose catabolic process
pentose metabolic process
primary metabolic process
small molecule metabolic process
Gene Properties
Blattner:b0063
Gene OrientationCounterclockwise
Centisome Percentage:1.47
Left Sequence End68348
Right Sequence End70048
Gene Sequence:
>1701 bp
ATGGCGATTGCAATTGGCCTCGATTTTGGCAGTGATTCTGTGCGAGCTTTGGCGGTGGAC
TGCGCTACCGGTGAAGAGATCGCCACCAGCGTAGAGTGGTATCCCCGTTGGCAGAAAGGG
CAATTTTGTGATGCCCCGAATAACCAGTTCCGTCATCATCCGCGTGACTACATTGAGTCA
ATGGAAGCGGCACTGAAAACCGTGCTTGCAGAGCTTAGCGTCGAACAGCGCGCAGCTGTG
GTCGGGATTGGCGTTGACAGTACCGGCTCGACGCCCGCACCGATTGATGCCGACGGAAAC
GTGCTGGCGCTGCGCCCGGAGTTTGCCGAAAACCCGAACGCGATGTTCGTATTGTGGAAA
GACCACACTGCGGTTGAAGAAGCGGAAGAGATTACCCGTTTGTGCCACGCGCCGGGCAAC
GTTGACTACTCCCGCTACATTGGTGGTATTTATTCCAGCGAATGGTTCTGGGCAAAAATC
CTGCATGTGACTCGCCAGGACAGCGCCGTGGCGCAATCTGCCGCATCGTGGATTGAGCTG
TGCGACTGGGTGCCAGCTCTGCTTTCCGGTACCACCCGCCCGCAGGATATTCGTCGCGGA
CGTTGCAGCGCCGGGCATAAATCTCTGTGGCACGAAAGCTGGGGCGGCCTGCCGCCAGCC
AGTTTCTTTGATGAGCTGGACCCGATCCTCAATCGCCATTTGCCTTCCCCGCTGTTCACT
GACACTTGGACTGCCGATATTCCGGTGGGCACCTTATGCCCGGAATGGGCGCAGCGTCTC
GGCCTGCCTGAAAGCGTGGTGATTTCCGGCGGCGCGTTTGACTGCCATATGGGCGCAGTT
GGCGCAGGCGCACAGCCTAACGCACTGGTAAAAGTTATCGGTACTTCCACCTGCGACATT
CTGATTGCCGACAAACAGAGCGTTGGCGAGCGGGCAGTTAAAGGTATTTGCGGTCAGGTT
GATGGCAGCGTGGTGCCTGGATTTATCGGTCTGGAAGCAGGCCAATCGGCGTTTGGTGAT
ATCTACGCCTGGTTTGGTCGCGTACTCGGCTGGCCGCTGGAACAGCTTGCCGCCCAGCAT
CCGGAACTGAAAACGCAAATCAACGCCAGCCAGAAACAACTGCTTCCGGCGCTGACCGAA
GCATGGGCCAAAAATCCGTCTCTGGATCACCTGCCGGTGGTGCTCGACTGGTTTAACGGC
CGCCGCACACCGAACGCTAACCAACGCCTGAAAGGGGTGATTACCGATCTTAACCTCGCT
ACCGACGCTCCGCTGCTGTTCGGCGGTTTGATTGCTGCCACCGCCTTTGGCGCACGCGCA
ATCATGGAGTGCTTTACCGATCAGGGGATCGCCGTTAATAACGTGATGGCACTGGGCGGC
ATCGCGCGGAAAAACCAGGTCATTATGCAGGCCTGCTGCGACGTGCTGAATCGCCCGCTG
CAAATTGTTGCCTCTGACCAGTGCTGTGCGCTCGGTGCGGCGATTTTTGCTGCCGTCGCC
GCGAAAGTGCACGCAGACATCCCATCAGCTCAGCAAAAAATGGCCAGTGCGGTAGAGAAA
ACCCTGCAACCGTGCAGCGAGCAGGCACAACGCTTTGAACAGCTTTATCGCCGCTATCAG
CAATGGGCGATGAGCGCCGAACAACACTATCTTCCAACTTCCGCCCCGGCACAGGCTGCC
CAGGCCGTTGCGACTCTATAA
Protein Properties
Pfam Domain Function:
Protein Residues:566
Protein Molecular Weight:61089
Protein Theoretical pI:5
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Ribulokinase
MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIES
MEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWK
DHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIEL
CDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFT
DTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDI
LIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQH
PELKTQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLA
TDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPL
QIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQ
QWAMSAEQHYLPTSAPAQAAQAVATL
References
External Links:
ResourceLink
Uniprot ID:P08204
Uniprot Name:ARAB_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674309
Ecogene ID:EG10053
Ecocyc:EG10053
ColiBase:b0063
Kegg Gene:b0063
EchoBASE ID:EB0051
CCDB:ARAB_ECOLI
BacMap:16128057
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Lee, N., Carbon, J. (1977). "Nucleotide sequence of the 5' end of araBAD operon messenger RNA in Escherichia coli B/r." Proc Natl Acad Sci U S A 74:49-53. Pubmed: 189315
  • Lee, N., Gielow, W., Martin, R., Hamilton, E., Fowler, A. (1986). "The organization of the araBAD operon of Escherichia coli." Gene 47:231-244. Pubmed: 3549454
  • Smith, B. R., Schleif, R. (1978). "Nucleotide sequence of the L-arabinose regulatory region of Escherichia coli K12." J Biol Chem 253:6931-6933. Pubmed: 357433
  • Yura, T., Mori, H., Nagai, H., Nagata, T., Ishihama, A., Fujita, N., Isono, K., Mizobuchi, K., Nakata, A. (1992). "Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region." Nucleic Acids Res 20:3305-3308. Pubmed: 1630901