| Record Information |
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| Version | 2.0 |
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| Creation Date | 2012-05-31 13:57:21 -0600 |
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| Update Date | 2015-09-17 16:24:10 -0600 |
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| Secondary Accession Numbers | |
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| Identification |
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| Name: | Sodium |
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| Description | Sodium is a metallic element that is soluble in water in nearly all of its compounds, and is thus present in great quantities in the Earth's oceans and other stagnant bodies of water. In these bodies it is mostly counterbalanced by the chloride ion, causing evaporated ocean water solids to consist mostly of sodium chloride, or common table salt. Sodium ion is also a component of many minerals. Export of sodium from the cell provides the driving force for several secondary active transporters membrane transport proteins, which import glucose, amino acids, and other nutrients into the cell by use of the sodium gradient. |
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| Structure | |
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| Synonyms: | |
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| Chemical Formula: | Na |
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| Weight: | Average: 22.9898
Monoisotopic: 22.989769675 |
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| InChI Key: | FKNQFGJONOIPTF-UHFFFAOYSA-N |
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| InChI: | InChI=1S/Na/q+1 |
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| CAS number: | 7440-23-5 |
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| IUPAC Name: | sodium(1+) ion |
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| Traditional IUPAC Name: | sodium(1+) ion |
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| SMILES: | [Na+] |
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| Chemical Taxonomy |
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| Description | belongs to the class of inorganic compounds known as homogeneous alkali metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkali metal atom. |
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| Kingdom | Inorganic compounds |
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| Super Class | Homogeneous metal compounds |
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| Class | Homogeneous alkali metal compounds |
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| Sub Class | Not Available |
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| Direct Parent | Homogeneous alkali metal compounds |
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| Alternative Parents | Not Available |
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| Substituents | |
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| Molecular Framework | Not Available |
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| External Descriptors | |
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| Physical Properties |
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| State: | Solid |
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| Charge: | 1 |
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| Melting point: | 97.82 °C |
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| Experimental Properties: | |
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| Predicted Properties | |
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| Biological Properties |
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| Cellular Locations: | Cytoplasm |
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| Reactions: | |
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| SMPDB Pathways: | |
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| KEGG Pathways: | - ABC transporters ec02010
- Biosynthesis of siderophore group nonribosomal peptides ec01053
- D-Glutamine and D-glutamate metabolism ec00471
- Galactose metabolism ec00052
- Glutathione metabolism ec00480
- Methane metabolism ec00680
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| EcoCyc Pathways: | Not Available |
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| Concentrations |
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| | Concentration | Strain | Media | Growth Status | Growth System | Temperature | Details |
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| 188000± 3000 uM | K12 | 16 mM NaH2PO4; 32 mM Na2HPO4; 5 mM (NH4)2SO4; 40 mM NaCl; 5 mM KCl; 0.4 mM MgSO4, 55 mM glucose | Stationary Phase (50 mM chloride in media) | Shake flask | 37 oC | PMID: 13909522 | | 70000± 2000 uM | K12 | 16 mM NaH2PO4; 32 mM Na2HPO4; 5 mM (NH4)2SO4; 40 mM NaCl; 5 mM KCl; 0.4 mM MgSO4, 55 mM glucose | Mid-Log Phase (50 mM chloride in media) | Shake flask | 37 oC | PMID: 13909522 | | 5000± 0 uM | K-12 | Not Available | Not Available | Not Available | Not Available | 1. Cybercell Database: http://ccdb.wishartlab.com/CCDB/cgi-bin/STAT_NEW.cgi
2. Phillips R., Kondev, J., Theriot, J. (2008) “Physical Biology of the Cell” Garland Science, New York, NY. |
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| Spectra |
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| Spectra: | |
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| References |
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| References: | - Achard JM, Hadchouel J, Faure S, Jeunemaitre X: Inherited sodium avid states. Adv Chronic Kidney Dis. 2006 Apr;13(2):118-23. Pubmed: 16580612
- Felder RA, Jose PA: Mechanisms of disease: the role of GRK4 in the etiology of essential hypertension and salt sensitivity. Nat Clin Pract Nephrol. 2006 Nov;2(11):637-50. Pubmed: 17066056
- Fox CS, Larson MG, Hwang SJ, Leip EP, Rifai N, Levy D, Benjamin EJ, Murabito JM, Meigs JB, Vasan RS: Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample. Kidney Int. 2006 Jun;69(11):2064-9. Pubmed: 16572107
- Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114. Pubmed: 22080510
- Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. Pubmed: 21097882
- SCHULTZ, S. G., WILSON, N. L., EPSTEIN, W. (1962). "Cation transport in Escherichia coli. II. Intracellular chloride concentration." J Gen Physiol 46:159-166. Pubmed: 13909522
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| Synthesis Reference: | Not Available |
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| Material Safety Data Sheet (MSDS) | Download (PDF) |
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| Links |
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| External Links: | |
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