Identification
Name:Uncharacterized transporter yaaJ
Synonyms:Not Available
Gene Name:yaaJ
Enzyme Class:Not Available
Biological Properties
General Function:Involved in sodium:amino acid symporter activity
Specific Function:Specific function unknown
Cellular Location:Cell inner membrane; Multi-pass membrane protein (Potential)
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Transports:
Transport References:
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
Metabolites:
ECMDB IDNameView
ECMDB00123GlycineMetaboCard
ECMDB00161L-AlanineMetaboCard
ECMDB02908SodiumMetaboCard
GO Classification:
Component
cell part
membrane
Function
organic acid transmembrane transporter activity
organic acid:sodium symporter activity
sodium:amino acid symporter activity
substrate-specific transmembrane transporter activity
transmembrane transporter activity
transporter activity
Process
cation transport
establishment of localization
ion transport
monovalent inorganic cation transport
sodium ion transport
transport
Gene Properties
Blattner:b0007
Gene OrientationCounterclockwise
Centisome Percentage:0.14
Left Sequence End6529
Right Sequence End7959
Gene Sequence:
>1431 bp
ATGCCAGATTTTTTCTCCTTCATTAACAGCGTCCTTTGGGGATCGGTAATGATTTACCTG
CTCTTCGGCGCAGGTTGTTGGTTCACTTTTCGCACCGGATTTGTGCAGTTTCGCTACATC
CGCCAGTTTGGCAAAAGTCTTAAAAATAGCATTCATCCACAGCCAGGCGGTTTAACCTCA
TTTCAGTCATTGTGTACCAGTCTTGCGGCGCGCGTGGGTAGCGGCAACCTGGCCGGCGTT
GCGCTGGCTATTACCGCCGGTGGACCTGGAGCCGTCTTTTGGATGTGGGTTGCCGCGTTT
ATCGGCATGGCGACCTCGTTTGCCGAATGTTCTCTGGCACAACTTTATAAAGAACGTGAC
GTCAATGGGCAGTTTCGTGGCGGACCGGCATGGTATATGGCGCGCGGGCTGGGGATGCGC
TGGATGGGCGTTCTGTTCGCCGTCTTTTTGCTCATCGCCTATGGCATAATTTTCAGCGGA
GTTCAAGCGAACGCCGTTGCCCGCGCCCTGAGTTTTTCTTTTGATTTTCCCCCGCTGGTG
ACAGGCATTATTCTCGCTGTCTTTACTCTGCTGGCAATCACTCGCGGTCTTCATGGCGTC
GCCCGGCTCATGCAGGGCTTTGTCCCGTTGATGGCGATAATCTGGGTACTGACCAGCCTG
GTAATTTGCGTAATGAATATCGGGCAACTTCCCCACGTCATTTGGTCTATTTTTGAGAGT
GCTTTTGGCTGGCAGGAAGCGGCAGGCGGCGCGGCGGGATATACCTTAAGCCAGGCGATT
ACTAACGGTTTTCAGCGCAGTATGTTTTCCAATGAGGCGGGAATGGGTTCGACGCCAAAC
GCGGCAGCGGCAGCGGCGTCCTGGCCTCCGCATCCGGCAGCGCAAGGGATTGTCCAGATG
ATTGGCATTTTTATCGACACCCTGGTCATCTGTACGGCAAGCGCCATGCTGATATTACTG
GCGGGTAACGGCACAACCTACATGCCGCTGGAAGGTATTCAGCTTATCCAGAAGGCGATG
CGGGTGCTAATGGGTTCCTGGGGTGCTGAGTTTGTTACCCTTGTGGTTATTCTGTTTGCC
TTCAGCTCCATCGTTGCCAACTACATTTATGCCGAAAACAATCTCTTCTTTTTACGCCTG
AACAACCCTAAAGCGATCTGGTGTTTGCGGATCTGCACCTTCGCAACGGTCATCGGCGGC
ACCTTGCTAAGCCTTCCGCTGATGTGGCAACTGGCAGATATCATAATGGCCTGCATGGCT
ATTACCAATTTGACCGCCATTTTACTGCTCTCGCCTGTGGTTCATACCATTGCCAGTGAT
TATCTACGCCAGCGTAAACTCGGCGTGCGCCCGGTGTTTGATCCATTGCGTTATCCGGAT
ATCGGTCGCCAGCTTTCTCCGGACGCGTGGGATGATGTTTCGCAGGAGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:476
Protein Molecular Weight:51662
Protein Theoretical pI:9
Signaling Regions:
  • None
Transmembrane Regions:
  • 4-24
  • 81-101
  • 141-161
  • 174-194
  • 207-227
  • 233-253
  • 300-320
  • 351-371
  • 391-411
  • 414-434
Protein Sequence:
>Uncharacterized transporter yaaJ
MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFGKSLKNSIHPQPGGLTS
FQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIGMATSFAECSLAQLYKERD
VNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSGVQANAVARALSFSFDFPPLV
TGIILAVFTLLAITRGLHGVARLMQGFVPLMAIIWVLTSLVICVMNIGQLPHVIWSIFES
AFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMGSTPNAAAAAASWPPHPAAQGIVQM
IGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQLIQKAMRVLMGSWGAEFVTLVVILFA
FSSIVANYIYAENNLFFLRLNNPKAIWCLRICTFATVIGGTLLSLPLMWQLADIIMACMA
ITNLTAILLLSPVVHTIASDYLRQRKLGVRPVFDPLRYPDIGRQLSPDAWDDVSQE
References
External Links:
ResourceLink
Uniprot ID:P30143
Uniprot Name:YAAJ_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:21321898
Ecogene ID:EG11555
Ecocyc:EG11555
ColiBase:b0007
Kegg Gene:b0007
EchoBASE ID:EB1516
CCDB:YAAJ_ECOLI
BacMap:16128001
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Yura, T., Mori, H., Nagai, H., Nagata, T., Ishihama, A., Fujita, N., Isono, K., Mizobuchi, K., Nakata, A. (1992). "Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region." Nucleic Acids Res 20:3305-3308. Pubmed: 1630901