Protein maoC (P77455)

Identification
Name:Protein maoC
Synonyms:
  • Phenylacetic acid degradation protein paaZ
Gene Name:maoC
Enzyme Class:
Biological Properties
General Function:Involved in oxidoreductase activity
Specific Function:Specific function unknown
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
  • Microbial metabolism in diverse environments ec01120
  • Phenylalanine metabolism ec00360
KEGG Reactions:
1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde + 1.0NADP + 1.0Water ↔ 1.03-Oxo-5,6-dehydrosuberyl-CoA + 1.0NADPH + 1.0Hydrogen ion
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde+1.0Thumb
1.02-Oxepin-2(3H)-ylideneacetyl-CoA + 1.0Water ↔ 1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde + 1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
ReactionCard
SMPDB Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde + 1.0Water + 1.0NADP → 1.0Hydrogen ion + 1.0NADPH + 1.03-Oxo-5,6-dehydrosuberyl-CoA
ReactionCard
EcoCyc Reactions:
1.0Thumb+2.0Thumb+1.0Thumb → 1.0Thumb+2.0Thumb+1.0Thumb
1.02-Oxepin-2(3H)-ylideneacetyl-CoA + 2.0Water + 1.0NADP → 1.03-Oxo-5,6-dehydrosuberyl-CoA + 2.0Hydrogen ion + 1.0NADPH
ReactionCard
1.0a (3S)-3-hydroxyacyl-CoA ← 1.0a trans-2-enoyl-CoA+1.0Thumb
1.0a (3S)-3-hydroxyacyl-CoA ← 1.0a trans-2-enoyl-CoA + 1.0Water
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.02-Oxepin-2(3H)-ylideneacetyl-CoA + 1.0NADP + 1.0Water → 1.03-Oxo-5,6-dehydrosuberyl-CoA + 1.0NADPH + 1.0Hydrogen ion
ReactionCard
1.0Thumb+1.0Thumb → 1.03-oxo-5,6-dehydrosuberyl-CoA semialdehyde
1.02-Oxepin-2(3H)-ylideneacetyl-CoA + 1.0Water → 1.03-oxo-5,6-dehydrosuberyl-CoA semialdehyde
ReactionCard
1.03-oxo-5,6-dehydrosuberyl-CoA semialdehyde+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.03-oxo-5,6-dehydrosuberyl-CoA semialdehyde + 1.0NADP + 1.0Water → 1.03-Oxo-5,6-dehydrosuberyl-CoA + 1.0NADPH + 1.0Hydrogen ion
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb
1.02-Oxepin-2(3H)-ylideneacetyl-CoA + 1.0Water → 1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.03-Oxo-5,6-dehydrosuberyl-CoA semialdehyde + 1.0NADP + 1.0Water → 1.03-Oxo-5,6-dehydrosuberyl-CoA + 1.0NADPH
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB211642-Oxepin-2(3H)-ylideneacetyl-CoAMetaboCard
ECMDB211723-Oxo-5,6-dehydrosuberyl-CoAMetaboCard
ECMDB231583-Oxo-5,6-dehydrosuberyl-CoA semialdehydeMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB00217NADPMetaboCard
ECMDB04111NADPHMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
catalytic activity
oxidoreductase activity
Process
metabolic process
oxidation reduction
Gene Properties
Blattner:b1387
Gene OrientationCounterclockwise
Centisome Percentage:31.24
Left Sequence End1449621
Right Sequence End1451666
Gene Sequence:
>2046 bp
ATGCAGCAGTTAGCCAGTTTCTTATCCGGTACCTGGCAGTCTGGCCGGGGCCGTAGCCGT
TTGATTCACCACGCTATTAGCGGCGAGGCGTTATGGGAAGTGACCAGTGAAGGTCTTGAT
ATGGCGGCTGCCCGCCAGTTTGCCATTGAAAAAGGTGCCCCCGCCCTTCGCGCTATGACC
TTTATCGAACGTGCGGCGATGCTTAAAGCGGTCGCTAAACATCTGCTGAGTGAAAAAGAG
CGTTTCTATGCTCTTTCTGCGCAAACAGGCGCAACGCGGGCAGACAGTTGGGTTGATATT
GAAGGTGGCATTGGGACGTTATTTACTTACGCCAGCCTCGGTAGCCGGGAGCTGCCTGAC
GATACGCTGTGGCCGGAAGATGAATTGATCCCCTTATCGAAAGAAGGTGGATTTGCCGCG
CGCCATTTACTGACCTCAAAGTCAGGCGTGGCAGTGCATATTAACGCCTTTAACTTCCCC
TGCTGGGGAATGCTGGAAAAGCTGGCACCAACGTGGCTGGGCGGAATGCCAGCCATCATC
AAACCAGCTACCGCGACGGCCCAACTGACTCAGGCGATGGTGAAATCAATTGTCGATAGT
GGTCTTGTTCCCGAAGGCGCAATTAGTCTGATCTGCGGTAGTGCTGGCGACTTGTTGGAT
CATCTGGACAGCCAGGATGTGGTGACTTTCACGGGGTCAGCGGCGACCGGACAGATGCTG
CGAGTTCAGCCAAATATCGTCGCCAAATCTATCCCCTTCACTATGGAAGCTGATTCCCTG
AACTGCTGCGTACTGGGCGAAGATGTCACCCCGGATCAACCGGAGTTTGCGCTGTTTATT
CGTGAAGTTGTGCGTGAGATGACCACAAAAGCCGGGCAAAAATGTACGGCAATCCGGCGG
ATTATTGTGCCGCAGGCATTGGTTAATGCTGTCAGTGATGCTCTGGTTGCGCGATTACAG
AAAGTCGTGGTCGGTGATCCTGCTCAGGAAGGCGTGAAAATGGGCGCACTGGTAAATGCT
GAGCAGCGTGCCGATGTGCAGGAAAAAGTGAACATATTGCTGGCTGCAGGATGCGAGATT
CGCCTCGGTGGTCAGGCGGATTTATCTGCTGCGGGTGCCTTCTTCCCGCCAACCTTATTG
TACTGTCCGCAGCCGGATGAAACACCGGCGGTACATGCAACAGAAGCCTTTGGCCCTGTC
GCAACGCTGATGCCAGCACAAAACCAGCGACATGCTCTGCAACTGGCTTGTGCAGGCGGC
GGTAGCCTTGCGGGAACGCTGGTGACGGCTGATCCGCAAATTGCGCGTCAGTTTATTGCC
GACGCGGCACGTACGCATGGGCGAATTCAGATCCTCAATGAAGAGTCGGCAAAAGAATCC
ACCGGGCATGGCTCCCCACTGCCACAACTGGTACATGGTGGGCCTGGTCGCGCAGGAGGC
GGTGAAGAATTAGGCGGTTTACGAGCGGTGAAACATTACATGCAGCGAACCGCTGTTCAG
GGTAGTCCGACGATGCTTGCCGCTATCAGTAAACAGTGGGTGCGCGGTGCGAAAGTCGAA
GAAGATCGTATTCATCCGTTCCGCAAATATTTTGAGGAGCTACAACCAGGCGACAGCCTG
TTGACTCCCCGCCGCACAATGACAGAGGCCGATATTGTTAACTTTGCTTGCCTCAGCGGC
GATCATTTCTATGCACATATGGATAAGATTGCTGCTGCCGAATCTATTTTCGGTGAGCGG
GTGGTGCATGGGTATTTTGTGCTTTCTGCGGCTGCGGGTCTGTTTGTCGATGCCGGTGTC
GGTCCGGTCATTGCTAACTACGGGCTGGAAAGCTTGCGTTTTATCGAACCCGTAAAGCCA
GGCGATACCATCCAGGTGCGTCTCACCTGTAAGCGCAAGACGCTGAAAAAACAGCGTAGC
GCAGAAGAAAAACCAACAGGTGTGGTGGAATGGGCTGTAGAGGTATTCAATCAGCATCAA
ACCCCGGTGGCGCTGTATTCAATTCTGACGCTGGTGGCCAGGCAGCACGGTGATTTTGTC
GATTAA
Protein Properties
Pfam Domain Function:
Protein Residues:681
Protein Molecular Weight:73002
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Protein maoC
MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAARQFAIEKGAPALRAMT
FIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEGGIGTLFTYASLGSRELPD
DTLWPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFPCWGMLEKLAPTWLGGMPAII
KPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDLLDHLDSQDVVTFTGSAATGQML
RVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEFALFIREVVREMTTKAGQKCTAIRR
IIVPQALVNAVSDALVARLQKVVVGDPAQEGVKMGALVNAEQRADVQEKVNILLAAGCEI
RLGGQADLSAAGAFFPPTLLYCPQPDETPAVHATEAFGPVATLMPAQNQRHALQLACAGG
GSLAGTLVTADPQIARQFIADAARTHGRIQILNEESAKESTGHGSPLPQLVHGGPGRAGG
GEELGGLRAVKHYMQRTAVQGSPTMLAAISKQWVRGAKVEEDRIHPFRKYFEELQPGDSL
LTPRRTMTEADIVNFACLSGDHFYAHMDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGV
GPVIANYGLESLRFIEPVKPGDTIQVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQ
TPVALYSILTLVARQHGDFVD
References
External Links:
ResourceLink
Uniprot ID:P77455
Uniprot Name:MAOC_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1742267
Ecogene ID:EG13735
Ecocyc:EG13735
ColiBase:b1387
Kegg Gene:b1387
EchoBASE ID:EB3498
CCDB:MAOC_ECOLI
BacMap:16129348
General Reference:
  • Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kasai, H., Kashimoto, K., Kimura, S., Kitakawa, M., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomura, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Horiuchi, T., et, a. l. .. (1996). "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." DNA Res 3:363-377. Pubmed: 9097039
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Ferrandez, A., Garcia, J. L., Diaz, E. (2000). "Transcriptional regulation of the divergent paa catabolic operons for phenylacetic acid degradation in Escherichia coli." J Biol Chem 275:12214-12222. Pubmed: 10766858
  • Ferrandez, A., Minambres, B., Garcia, B., Olivera, E. R., Luengo, J. M., Garcia, J. L., Diaz, E. (1998). "Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway." J Biol Chem 273:25974-25986. Pubmed: 9748275
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553