Identification
Name:Autoinducer 2 import ATP-binding protein LsrA
Synonyms:Not Available
Gene Name:lsrA
Enzyme Class:Not Available
Biological Properties
General Function:ATPase activity, coupled to transmembrane movement of substances
Specific Function:Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (Probable). This protein is essential for aerobic growth.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
SMPDB Reactions:
1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran+1.0Phosphoribosyl-ATP+1.0Thumb+1.0Thumb+1.0Thumb1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran+1.0Adenosine diphosphate+1.0Thumb+1.0Pyrophosphate+1.0Thumb
1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + 1.0Phosphoribosyl-ATP + 1.0Water + 1.0(2R,4S)-2-Methyl-2,3,3,4-tetrahydroxytetrahydrofuran + 1.0Phosphoribosyl-ATP → 1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0Pyrophosphate + 1.0ADP
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21368(2R,4S)-2-Methyl-2,3,3,4-tetrahydroxytetrahydrofuranMetaboCard
ECMDB01341ADPMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB04138Phosphoribosyl-ATPMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
ATP binding
ATPase activity, coupled to transmembrane movement of substances
integral component of membrane
plasma membrane
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1536
atgcaaacgagtgatacccgcgcgttaccgctactttgcgcccgctcggtttataaacag
tattcaggggtcaatgtcctgaaaggcatcgattttacgttgcatcagggggaggtccac
gccctgctcggcggcaatggtgccggtaaatcgacgttaatgaagattattgccggtatt
acccctgctgatagcggtacgctggagattgagggcaacaactacgtcagattaacgcca
gttcatgctcatcagctgggtatttatctcgttccccaggaaccgctgcttttcccaagc
ctgtcgataaaagaaaacatcctgtttgggctggcaaaaaaacagctctccatgcagaaa
atgaagaacttgctggcggcgctgggctgccagtttgatctgcatagtctggcaggatcg
ctggatgtcgccgatcgccaaatggtggaaatcctccgcgggctgatgcgcgactcgcgg
attctgatcctcgatgaacctaccgcctcgcttacccctgcggaaaccgaacgcttgttt
agtcgcttgcaagagctgcttgctactggcgtgggtattgtttttatctcgcataagctg
ccggaaattcgccagattgccgatcgaattagcgtgatgcgcgacggaaccatcgcctta
agcggcaaaaccagcgaactgtctaccgacgacattattcaggccatcaccccagcggta
cgggaaaaatcgctctctgccagccaaaaattatggctggagttacctggtaaccgccca
caacatgccgccggaacgccggtgctgacactggaaaatctgaccggcgaaggtttcagg
aatgtcagcctgacgctcaatgccggagaaattctgggcctggctgggctggtgggggcc
ggacgcacagaactggccgagacgctctatggtctgcgtactttgcgtggcggacgcatt
atgctgaatggtaaagagatcaataaattatccactggagaacgtttactgcgcggtctg
gtttatctgccggaagatcgccagtcatccggactgaatctcgatgcttcgctggcctgg
aacgtctgcgcccttactcataaccttcgtggattctgggcgaaaaccgcgaaagataat
gccaccctggaacgttatcgtcgggcgctgaatattaaattcaaccaaccggaacaagct
gcacggacattatccggtggcaaccagcaaaaaatcctcattgccaaatgcttggaagct
tcgccgcaagtattgattgtcgatgagccgacgcgcggcgtggatgtctcggcccgtaat
gatatctaccagctgttgcgcagcatcgccgcacaaaatgtggctgtgctgcttatctcc
tccgacctggaagagatcgaactgatggcagatcgtgtgtatgtgatgcatcagggcgaa
attacccactctgcactgaccgagcgcgatattaatgtcgagactattatgcgcgttgcc
ttcggcgatagtcagcgtcaggaggcgtcatgctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:511
Protein Molecular Weight:55820
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Autoinducer 2 import ATP-binding protein LsrA
MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLGGNGAGKSTLMKIIAGI
TPADSGTLEIEGNNYVRLTPVHAHQLGIYLVPQEPLLFPSLSIKENILFGLAKKQLSMQK
MKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSRILILDEPTASLTPAETERLF
SRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTIALSGKTSELSTDDIIQAITPAV
REKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTGEGFRNVSLTLNAGEILGLAGLVGA
GRTELAETLYGLRTLRGGRIMLNGKEINKLSTGERLLRGLVYLPEDRQSSGLNLDASLAW
NVCALTHNLRGFWAKTAKDNATLERYRRALNIKFNQPEQAARTLSGGNQQKILIAKCLEA
SPQVLIVDEPTRGVDVSARNDIYQLLRSIAAQNVAVLLISSDLEEIELMADRVYVMHQGE
ITHSALTERDINVETIMRVAFGDSQRQEASC
References
External Links:
ResourceLink
Uniprot ID:P77257
Uniprot Name:LSRA_ECOLI
CCDB:LSRA_ECOLI
General Reference:Not Available