Identification
Name:Autoinducer 2-binding protein LsrB
Synonyms:Not Available
Gene Name:lsrB
Enzyme Class:Not Available
Biological Properties
General Function:periplasmic space
Specific Function:Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable).
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
SMPDB Reactions:
1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran+1.0Phosphoribosyl-ATP+1.0Thumb+1.0Thumb+1.0Thumb1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran+1.0Adenosine diphosphate+1.0Thumb+1.0Pyrophosphate+1.0Thumb
1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + 1.0Phosphoribosyl-ATP + 1.0Water + 1.0(2R,4S)-2-Methyl-2,3,3,4-tetrahydroxytetrahydrofuran + 1.0Phosphoribosyl-ATP → 1.0(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0Pyrophosphate + 1.0ADP
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21368(2R,4S)-2-Methyl-2,3,3,4-tetrahydroxytetrahydrofuranMetaboCard
ECMDB01341ADPMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB04138Phosphoribosyl-ATPMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
ATP-binding cassette (ABC) transporter complex
periplasmic space
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1023
atgacacttcatcgctttaagaaaatcgccttacttagcgctcttggcattgccgcaatc
tctatgaatgtgcaggccgcagagcgtattgcatttattcccaaactggttggcgtggga
ttttttaccagcggtggcaacggcgcacaacaagcgggtaaagagctgggcgttgatgtg
acctacgacgggccgacagaacccagtgtttctggtcaggtacagttgattaataacttc
gtcaatcaaggttataacgccattatcgtttctgcggtttcgcctgatggcttgtgtccg
gcactgaaacgcgccatgcaacgtggtgtgagagtgctgacctgggactctgatactaaa
ccggagtgccgctcttactacattaatcagggaacgcccgcccagttaggaggtatgttg
gtggatatggcggcgcgtcaggtgaataaagacaaagccaaagtcgcgtttttctactca
agccccaccgttacggaccaaaaccagtgggtgaaagaagcgaaagcgaaaatcgccaaa
gagcatccaggctgggaaattgtcactacgcagtttggctataacgatgccactaaatcg
ttacaaaccgcagaaggaatattaaaagcgtatagcgatctcgacgccattatcgccccc
gatgccaacgccctgcccgctgccgcacaagccgcagaaaacttgaaaaatgacaaagta
gcgattgtcggattcagtacgccaaatgtgatgcgcccgtatgtagagcgcggcacggtg
aaagaatttggcctgtgggatgtggttcagcaaggcaaaatttcagtgtatgtcgcggat
gcattattgaaaaaaggatcaatgaaaacgggcgacaagctggatatcaagggcgtaggt
caggttgaagtctcgccaaacagcgttcagggctatgactacgaagcggatggtaatggc
atcgtactgttaccggagcgcgtgatattcaacaaagagaatatcggcaaatacgatttc
tga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:340
Protein Molecular Weight:36684
Protein Theoretical pI:Not Available
Signaling Regions:
  • 1-26
Transmembrane Regions:Not Available
Protein Sequence:
>Autoinducer 2-binding protein LsrB
MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTSGGNGAQQAGKELGVDV
TYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPALKRAMQRGVRVLTWDSDTK
PECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYSSPTVTDQNQWVKEAKAKIAK
EHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAIIAPDANALPAAAQAAENLKNDKV
AIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISVYVADALLKKGSMKTGDKLDIKGVG
QVEVSPNSVQGYDYEADGNGIVLLPERVIFNKENIGKYDF
References
External Links:
ResourceLink
Uniprot ID:P76142
Uniprot Name:LSRB_ECOLI
CCDB:LSRB_ECOLI
General Reference:Not Available