Identification
Name:Putative aliphatic sulfonates transport permease protein ssuC
Synonyms:Not Available
Gene Name:ssuC
Enzyme Class:Not Available
Biological Properties
General Function:Involved in transporter activity
Specific Function:Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:
KEGG Pathways:
Transports:
Transport References:
  • Uniprot Consortium (2012). "Reorganizing the protein space at the Universal Protein Resource (UniProt)." Nucleic Acids Res 40:D71-D75. Pubmed: 22102590
SMPDB Reactions:
1.0Alkyl Sulfate+1.0Thumb+1.0Thumb1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Alkyl Sulfate+1.0Thumb
1.0Alkyl Sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Alkyl Sulfate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Butanesulfonate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0 ethanesulfonate → 1.0Hydrogen ion + 1.0Phosphate + 1.0Adenosine diphosphate + 1.0 ethanesulfonate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0 isethionate → 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0Phosphate + 1.0 isethionate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0methanesulfonate + 1.0Methanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0methanesulfonate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb
1.0Cysteine-S-sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Cysteine-S-sulfate + 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0ADP
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Thumb+1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
Metabolites:
ECMDB IDNameView
ECMDB24254 ethanesulfonateMetaboCard
ECMDB24255 isethionateMetaboCard
ECMDB242533-(N-morpholino)propanesulfonateMetaboCard
ECMDB210023-Sulfopyruvic acidMetaboCard
ECMDB041955-L-Glutamyl-taurineMetaboCard
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB21313ButanesulfonateMetaboCard
ECMDB02757Cysteic acidMetaboCard
ECMDB00731Cysteine-S-sulfateMetaboCard
ECMDB21330EthanesulfonateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB21233Isethionic acidMetaboCard
ECMDB21344MethanesulfonateMetaboCard
ECMDB01429PhosphateMetaboCard
ECMDB01134Phosphoadenosine phosphosulfateMetaboCard
ECMDB01448SulfateMetaboCard
ECMDB00240SulfiteMetaboCard
ECMDB21358SulfoacetateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Component
cell part
membrane
Function
transporter activity
Process
establishment of localization
transport
Gene Properties
Blattner:b0934
Gene OrientationCounterclockwise
Centisome Percentage:21.41
Left Sequence End993264
Right Sequence End994055
Gene Sequence:
>792 bp
ATGGCAACGCCAGTGAAGAAGTGGTTATTGCGCGTTGCCCCCTGGTTTTTACCGGTGGGC
ATCGTGGCGGTGTGGCAACTGGCCTCCTCGGTTGGCTGGCTGTCGACGCGTATTTTGCCT
TCACCGGAAGGAGTGGTGACGGCGTTCTGGACGCTCTCCGCCAGCGGCGAACTGTGGCAG
CATCTGGCGATCAGCTCCTGGCGGGCGCTGATTGGCTTTTCAATTGGCGGATCGCTGGGG
TTGATTTTGGGACTGATTAGCGGGCTATCTCGCTGGGGAGAACGGCTGCTGGATACCTCA
ATTCAGATGTTGCGCAACGTGCCGCATCTGGCGCTGATCCCGCTGGTGATTTTGTGGTTT
GGCATTGATGAATCCGCAAAAATCTTTCTGGTGGCGCTCGGTACGCTATTCCCCATTTAT
ATCAACACCTGGCATGGCATCCGTAATATCGATCGCGGGTTGGTGGAGATGGCGCGTAGC
TATGGATTATCCGGCATACCGCTGTTTATCCATGTGATCCTGCCTGGTGCCCTGCCCTCA
ATTATGGTCGGCGTGCGTTTTGCGTTGGGCCTGATGTGGCTGACGCTGATTGTTGCCGAA
ACCATTTCTGCCAATTCAGGCATTGGTTATCTGGCGATGAATGCGCGGGAGTTTTTGCAA
ACGGACGTGGTGGTAGTCGCTATTATTCTTTACGCCCTGCTCGGCAAACTGGCTGACGTC
AGCGCGCAGCTGTTAGAGCGCCTCTGGTTGCGCTGGAACCCGGCTTATCATTTGAAGGAG
GCCACGGTATGA
Protein Properties
Pfam Domain Function:
Protein Residues:263
Protein Molecular Weight:28925
Protein Theoretical pI:10
Signaling Regions:
  • None
Transmembrane Regions:
  • 14-34
  • 44-64
  • 69-89
  • 103-122
  • 126-148
  • 165-185
  • 188-208
  • 218-238
Protein Sequence:
>Putative aliphatic sulfonates transport permease protein ssuC
MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEGVVTAFWTLSASGELWQ
HLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWF
GIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPS
IMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADV
SAQLLERLWLRWNPAYHLKEATV
References
External Links:
ResourceLink
Uniprot ID:P75851
Uniprot Name:SSUC_ECOLI
GenBank Gene ID:AJ237695
Genebank Protein ID:4583569
Ecogene ID:EG13705
Ecocyc:EG13705
ColiBase:b0934
Kegg Gene:b0934
EchoBASE ID:EB3469
CCDB:SSUC_ECOLI
BacMap:90111188
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Daley, D. O., Rapp, M., Granseth, E., Melen, K., Drew, D., von Heijne, G. (2005). "Global topology analysis of the Escherichia coli inner membrane proteome." Science 308:1321-1323. Pubmed: 15919996
  • Drew, D., Sjostrand, D., Nilsson, J., Urbig, T., Chin, C. N., de Gier, J. W., von Heijne, G. (2002). "Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis." Proc Natl Acad Sci U S A 99:2690-2695. Pubmed: 11867724
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • van Der Ploeg, J. R., Iwanicka-Nowicka, R., Bykowski, T., Hryniewicz, M. M., Leisinger, T. (1999). "The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl." J Biol Chem 274:29358-29365. Pubmed: 10506196