Soluble aldose sugar dehydrogenase yliI (P75804)

Identification
Name:Soluble aldose sugar dehydrogenase yliI
Synonyms:
  • Asd
Gene Name:yliI
Enzyme Class:Not Available
Biological Properties
General Function:Involved in oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
Specific Function:Aldose sugar dehydrogenase with broad substrate specificity. The physiological substrate is unknown. Can oxidize glucose to gluconolactone. Can also utilize D-arabinose, L- arabinose and 2-deoxy-glucose. Has higher activity towards oligomeric sugars, such as maltose, maltotriose or cellobiose. It may function to input sugar-derived electrons into the respiratory network
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
EcoCyc Reactions:
1.0an aldose+1.0an oxidized electron acceptor+1.0Thumb ? 1.0an aldonate+1.0a reduced electron acceptor
1.0an aldose + 1.0an oxidized electron acceptor + 1.0Water ? 1.0an aldonate + 1.0a reduced electron acceptor
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Ubiquinone-8 + 1.0D-Glucose + 1.0Water → 1.0Ubiquinol-8 + 1.0Gluconic acid + 1.0Hydrogen ion
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00122D-GlucoseMetaboCard
ECMDB00625Gluconic acidMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB01060Ubiquinol-8MetaboCard
ECMDB21296Ubiquinone-8MetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
binding
catalytic activity
cofactor binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor
quinone binding
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Blattner:b0837
Gene OrientationClockwise
Centisome Percentage:18.92
Left Sequence End877965
Right Sequence End879080
Gene Sequence:
>1116 bp
ATGTTCCCAAAAATAATGAATGATGAAAACTTTTTCAAAAAAGCGGCGGCGCACGGGGAG
GAACCTCCTTTAACTCCTCAAAACGAACATCAGCGGTCCGGGCTGCGCTTCGCCCGTCGC
GTCAGACTACCCCGTGCGGTTGGCCTGGCTGGCATGTTCTTACCGATTGCTTCAACGCTG
GTTTCACACCCGCCGCCGGGCTGGTGGTGGCTGGTGTTGGTCGGCTGGGCGTTCGTCTGG
CCGCATTTAGCCTGGCAGATAGCGAGCAGGGCCGTCGATCCGCTTAGCCGGGAAATTTAC
AACTTAAAAACCGATGCAGTATTAGCGGGAATGTGGGTAGGCGTAATGGGCGTAAACGTG
CTGCCTTCCACCGCGATGTTGATGATTATGTGTCTGAATTTGATGGGGGCAGGCGGCCCC
CGTCTGTTTGTCGCGGGTCTGGTGTTGATGGTGGTTTCCTGCCTTGTCACCCTCGAGCTG
ACGGGCATTACCGTGTCGTTCAATAGTGCGCCGCTGGAATGGTGGCTCTCCCTTCCCATT
ATTGTCATTTATCCTCTGCTGTTTGGCTGGGTCAGCTACCAGACGGCAACCAAACTGGCG
GAACATAAACGCAGGTTGCAGGTCATGAGTACCCGCGACGGCATGACGGGCGTGTATAAC
CGACGTCATTGGGAAACTATGTTACGCAATGAATTTGATAACTGTCGGCGGCATAATCGC
GATGCAACGTTACTGATTATCGATATCGACCATTTCAAGAGCATCAACGATACCTGGGGC
CATGATGTGGGCGATGAAGCGATTGTGGCGCTTACCCGACAGTTACAAATTACCCTGCGC
GGTAGCGATGTGATTGGTCGGTTTGGCGGCGATGAGTTTGCAGTAATCATGTCCGGTACG
CCAGCTGAGAGCGCCATTACCGCCATGTTACGGGTGCATGAAGGGCTAAATACATTACGT
TTGCCGAATACGCCACAGGTAACTTTACGGATTAGTGTGGGGGTTGCGCCGCTGAACCCA
CAAATGAGTCACTATCGTGAGTGGTTGAAATCGGCAGATTTGGCGCTTTACAAAGCAAAG
AAAGCCGGACGTAACCGCACCGAAGTGGCGGCCTGA
Protein Properties
Pfam Domain Function:
Protein Residues:371
Protein Molecular Weight:41054
Protein Theoretical pI:7
Signaling Regions:
  • 1-20
Transmembrane Regions:
  • None
Protein Sequence:
>Soluble aldose sugar dehydrogenase yliI
MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRH
WQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYG
RLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYLFIALGENNQRPTAQDLDKLQ
GKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDK
FPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDES
SGELLKVSPRN
References
External Links:
ResourceLink
Uniprot ID:P75804
Uniprot Name:YLII_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674526
Ecogene ID:EG13480
Ecocyc:EG13480
ColiBase:b0837
Kegg Gene:b0837
EchoBASE ID:EB3253
CCDB:YLII_ECOLI
BacMap:16128805
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • Southall, S. M., Doel, J. J., Richardson, D. J., Oubrie, A. (2006). "Soluble aldose sugar dehydrogenase from Escherichia coli: a highly exposed active site conferring broad substrate specificity." J Biol Chem 281:30650-30659. Pubmed: 16864586