L-Alanine (ECMDB00161) (M2MDB000063)
Record Information | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Version | 2.0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Creation Date | 2012-05-31 10:22:23 -0600 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Update Date | 2015-09-13 12:56:06 -0600 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Secondary Accession Numbers |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Identification | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Name: | L-Alanine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Description | Alanine is an amino acid made from the conversion of the carbohydrate pyruvate or the breakdown of DNA and the dipeptides carnosine and anserine. Alanine is an important participant as well as regulator in glucose metabolism. Normal alanine metabolism, like that of other amino acids, is highly dependent upon enzymes that contain vitamin B6. (http://www.dcnutrition.com/AminoAcids/) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Structure | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Synonyms: |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Chemical Formula: | C3H7NO2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Weight: | Average: 89.0932 Monoisotopic: 89.047678473 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
InChI Key: | QNAYBMKLOCPYGJ-REOHCLBHSA-N | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
InChI: | InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CAS number: | 56-41-7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IUPAC Name: | (2S)-2-aminopropanoic acid | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Traditional IUPAC Name: | L-alanine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SMILES: | C[C@H](N)C(O)=O | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Chemical Taxonomy | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Description | belongs to the class of organic compounds known as alanine and derivatives. Alanine and derivatives are compounds containing alanine or a derivative thereof resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Kingdom | Organic compounds | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Super Class | Organic acids and derivatives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Class | Carboxylic acids and derivatives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sub Class | Amino acids, peptides, and analogues | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Direct Parent | Alanine and derivatives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Alternative Parents | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Substituents |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Framework | Aliphatic acyclic compounds | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
External Descriptors |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Physical Properties | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
State: | Solid | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Charge: | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Melting point: | 300 °C | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Experimental Properties: |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Predicted Properties |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Biological Properties | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Locations: | Cytoplasm | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Reactions: | L-Alanine + Pyridoxal 5'-phosphate > Pyridoxamine 5'-phosphate + Pyruvic acid L-Alanine <> D-Alanine L-Cysteine + SufSE sulfur acceptor complex > L-Alanine + SufSE with bound sulfur alpha-Ketoglutarate + L-Alanine <> L-Glutamate + Pyruvic acid Adenosine triphosphate + Water + L-Alanine > ADP + L-Alanine + Hydrogen ion + Phosphate Adenosine triphosphate + Water + L-Alanine > ADP + L-Alanine + Hydrogen ion + Phosphate L-Alanine + Adenosine triphosphate + UDP-N-Acetylmuraminate <> ADP + Hydrogen ion + Phosphate + UDP-N-Acetylmuramoyl-L-alanine L-Alanine-L-glutamate + Water > L-Alanine + L-Glutamate L-Alanine + Pimeloyl-[acyl-carrier protein] > 8-Amino-7-oxononanoate + acyl carrier protein + Carbon dioxide L-Cysteine + IscS sulfur acceptor protein > L-Alanine + IscS with bound sulfur L-Alanine + Adenosine triphosphate + tRNA(Ala) > L-Alanyl-tRNA(Ala) + Adenosine monophosphate + Pyrophosphate 3-Sulfinoalanine + 2 Hydrogen ion > L-Alanine + Sulfur dioxide alpha-Ketoisovaleric acid + L-Alanine <> Pyruvic acid + L-Valine + a-Ketoisovaleric acid L-Valine + Pyruvic acid <> alpha-Ketoisovaleric acid + L-Alanine Adenosine triphosphate + L-Alanine + tRNA(Ala) + tRNA(Ala) <> Adenosine monophosphate + Pyrophosphate + L-Alanyl-tRNA + L-Alanyl-tRNA Adenosine triphosphate + UDP-N-Acetylmuraminate + L-Alanine <> ADP + Phosphate + UDP-N-Acetylmuramoyl-L-alanine 6-Carboxyhexanoyl-CoA + L-Alanine + Pimeloyl-[acyl-carrier protein] <> 8-Amino-7-oxononanoate + Coenzyme A + Carbon dioxide + Acyl-carrier protein Selenocysteine + Reduced acceptor <> Hydrogen selenide + L-Alanine + Acceptor N-Acetylmuramoyl-Ala + Water <> N-Acetyl-D-muramoate + L-Alanine [Enzyme]-cysteine + L-Cysteine <> [Enzyme]-S-sulfanylcysteine + L-Alanine UDP-N-Acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate-D-alanine + Water > L-Alanine + UDP-N-Acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate Hydrogen ion + L-Alanine + pimeloyl-CoA > Carbon dioxide + Coenzyme A + 8-Amino-7-oxononanoate Oxoglutaric acid + L-Alanine <> L-Glutamate + Pyruvic acid L-Alanine + Hydrogen ion + Pimeloyl-ACPs > 8-Amino-7-oxononanoate + Carbon dioxide + ACP L-Cysteine + a sulfur acceptor + Hydrogen ion L-Alanine + <i>S</i>-sulfanyl-[acceptor] 3-Sulfinoalanine + Water Hydrogen ion + L-Alanine + Sulfite More...L-Cysteine + L-Cysteine-Desulfurases > L-Alanine + Persulfurated-L-cysteine-desulfurases ala-asp + Water > L-Alanine + L-Aspartic acid ala-gln + Water > L-Alanine + L-Glutamine ala-gly + Water > L-Alanine + Glycine ala-his + Water > L-Alanine + L-Histidine ala-leu + Water > L-Alanine + L-Leucine ala-thr + Water > L-Alanine + L-Threonine L-Alanyl-L-Glutamate + Water > L-Alanine + L-Glutamate methionine-alanine dipeptide + Water > L-Methionine + L-Alanine a reduced electron acceptor + Selenocysteine <> L-Alanine + Selenium + an oxidized electron acceptor + Hydrogen ion L-Alanine + Oxoglutaric acid > Pyruvic acid + L-Glutamate L-Alanine > D-Alanine L-Valine + Pyruvic acid > a-Ketoisovaleric acid + L-Alanine 6-carboxyhexanoyl-CoA + L-Alanine > 8-Amino-7-oxononanoate + CoA + Carbon dioxide L-Cysteine + acceptor > L-Alanine + S-sulfanyl-acceptor Adenosine triphosphate + UDP-N-Acetylmuraminate + L-Alanine > ADP + Inorganic phosphate + UDP-N-Acetylmuramoyl-L-alanine Selenocysteine + reduced acceptor > Hydrogen selenide + L-Alanine + acceptor a pimeloyl-[acp] + L-Alanine + L-Alanine > Carbon dioxide + a holo-[acyl-carrier protein] + 8-Amino-7-oxononanoate a sulfurated [sulfur carrier] + L-Alanine + L-Alanine > 8-Amino-7-oxononanoate + Coenzyme A + Carbon dioxide L-Alanine + L-Alanine <> D-Alanine L-Alanine + L-Alanine > D-Alanine UDP-N-acetylmuraminate + Adenosine triphosphate + L-Alanine + UDP-N-Acetylmuraminate + L-Alanine > UDP-N-Acetylmuramoyl-L-alanine + Adenosine diphosphate + Phosphate + ADP Adenosine triphosphate + L-Alanine + tRNA(Ala) + L-Alanine > Adenosine monophosphate + Pyrophosphate + L-alanyl-tRNA(Ala) L-Alanine + Oxoglutaric acid + L-Alanine <> L-Glutamic acid + Pyruvic acid + L-Glutamate L-Alanine + Glyoxylic acid + L-Alanine <> Glycine + Pyruvic acid Pyruvic acid + L-Glutamic acid + L-Glutamate > Oxoglutaric acid + L-Alanine + L-Alanine L-Cysteine + an [L-cysteine desulfurase] L-cysteine persulfide > an [L-cysteine desulfurase] L-cysteine persulfide + L-Alanine + L-Alanine L-Valine + Pyruvic acid + L-Valine > L-Alanine + a-Ketoisovaleric acid + L-Alanine L-Alanine + Adenosine triphosphate + Hydrogen ion + tRNA(Ala) + L-Alanine > Pyrophosphate + Adenosine monophosphate + L-alanyl-tRNA(Ala) UDP-N-acetyl-α-D-muramate + L-Alanine + Adenosine triphosphate + L-Alanine > Adenosine diphosphate + Phosphate + Hydrogen ion + UDP-N-Acetylmuramoyl-L-alanine + ADP UDP-N-acetyl-α-D-muramate + Adenosine triphosphate + L-Alanine > UDP-N-Acetylmuramyl-L-Ala + ADP + Phosphate + Hydrogen ion 6 6-carboxyhexanoyl-CoA + L-Alanine + Pimeloyl-[acyl-carrier protein] <>8 8-Amino-7-oxononanoate + Coenzyme A + Carbon dioxide + Acyl-carrier protein Adenosine triphosphate + L-Alanine + tRNA(Ala) <> Adenosine monophosphate + Pyrophosphate + L-Alanyl-tRNA alpha-Ketoglutarate + L-Alanine <> L-Glutamate + Pyruvic acid N-Acetylmuramoyl-Ala + Water <> N-Acetyl-D-muramoate + L-Alanine [Enzyme]-cysteine + L-Cysteine <> [Enzyme]-S-sulfanylcysteine + L-Alanine L-Alanine + Adenosine triphosphate + UDP-N-Acetylmuraminate <> ADP + Hydrogen ion + Phosphate + UDP-N-Acetylmuramoyl-L-alanine L-Alanine <> D-Alanine Adenosine triphosphate + L-Alanine + tRNA(Ala) <> Adenosine monophosphate + Pyrophosphate + L-Alanyl-tRNA alpha-Ketoglutarate + L-Alanine <> L-Glutamate + Pyruvic acid N-Acetylmuramoyl-Ala + Water <> N-Acetyl-D-muramoate + L-Alanine [Enzyme]-cysteine + L-Cysteine <> [Enzyme]-S-sulfanylcysteine + L-Alanine L-Alanine + Adenosine triphosphate + UDP-N-Acetylmuraminate <> ADP + Hydrogen ion + Phosphate + UDP-N-Acetylmuramoyl-L-alanine alpha-Ketoglutarate + L-Alanine <> L-Glutamate + Pyruvic acid L-Alanine <> D-Alanine | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SMPDB Pathways: |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
KEGG Pathways: |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
EcoCyc Pathways: |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Concentrations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Find out more about how we convert literature concentrations. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Spectra | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Spectra: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
References | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
References: |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Synthesis Reference: | Chibata I; Kakimoto T; Kato J Enzymatic production of L-alanine by Pseudomonas dacunhae. Applied microbiology (1965), 13(5), 638-45. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Material Safety Data Sheet (MSDS) | Download (PDF) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Links | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
External Links: |
|
Enzymes
- General function:
- Involved in nucleotide binding
- Specific function:
- Edits incorrectly charged Ser-tRNA(Ala) and Gly- tRNA(Ala) but not incorrectly charged Ser-tRNA(Thr)
- Gene Name:
- alaS
- Uniprot ID:
- P00957
- Molecular weight:
- 96032
Reactions
ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). |
- General function:
- Involved in transferase activity
- Specific function:
- L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine
- Gene Name:
- avtA
- Uniprot ID:
- P09053
- Molecular weight:
- 46711
Reactions
L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. |
- General function:
- Involved in alanine racemase activity
- Specific function:
- Provides the D-alanine required for cell wall biosynthesis
- Gene Name:
- alr
- Uniprot ID:
- P0A6B4
- Molecular weight:
- 39153
Reactions
L-alanine = D-alanine. |
- General function:
- Involved in metabolic process
- Specific function:
- Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for NAD, biotin and Fe-S cluster synthesis. Transfers sulfur on 'Cys-456' of thiI in a transpersulfidation reaction. Transfers sulfur on 'Cys-19' of tusA in a transpersulfidation reaction. Functions also as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate
- Gene Name:
- iscS
- Uniprot ID:
- P0A6B7
- Molecular weight:
- 45089
Reactions
L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor. |
- General function:
- Involved in catalytic activity
- Specific function:
- Interconversion of serine and glycine
- Gene Name:
- glyA
- Uniprot ID:
- P0A825
- Molecular weight:
- 45316
Reactions
5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine. |
- General function:
- Involved in 8-amino-7-oxononanoate synthase activity
- Specific function:
- Catalyzes the decarboxylative condensation of pimeloyl- CoA and L-alanine to produce 8-amino-7-oxononanoate (AON), coenzyme A, and carbon dioxide
- Gene Name:
- bioF
- Uniprot ID:
- P12998
- Molecular weight:
- 41594
Reactions
6-carboxyhexanoyl-CoA + L-alanine = 8-amino-7-oxononanoate + CoA + CO(2). |
- General function:
- Involved in hydrolase activity
- Specific function:
- Dipeptidase with broad substrate specificity. Requires dipeptide substrates with an unblocked N-terminus and the amino group in the alpha or beta position. Non-protein amino acids and proline are not accepted in the C-terminal position, whereas some dipeptide amides and formyl amino acids are hydrolyzed. Also shows cysteinylglycinase activity, which is sufficient for E.coli to utilize cysteinylglycine as a cysteine source
- Gene Name:
- pepD
- Uniprot ID:
- P15288
- Molecular weight:
- 52915
Reactions
Hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids. |
- General function:
- Involved in ATP binding
- Specific function:
- Cell wall formation
- Gene Name:
- murC
- Uniprot ID:
- P17952
- Molecular weight:
- 53626
Reactions
ATP + UDP-N-acetylmuramate + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine. |
- General function:
- Involved in N-acetylmuramoyl-L-alanine amidase activity
- Specific function:
- Cell-wall hydrolase probably involved in cell-wall hydrolysis, septation or recycling
- Gene Name:
- amiB
- Uniprot ID:
- P26365
- Molecular weight:
- 47985
Reactions
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. |
- General function:
- Involved in alanine racemase activity
- Specific function:
- Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by dadA
- Gene Name:
- dadX
- Uniprot ID:
- P29012
- Molecular weight:
- 38844
Reactions
L-alanine = D-alanine. |
- General function:
- Involved in N-acetylmuramoyl-L-alanine amidase activity
- Specific function:
- Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides
- Gene Name:
- amiA
- Uniprot ID:
- P36548
- Molecular weight:
- 31412
Reactions
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. |
- General function:
- Involved in N-acetylmuramoyl-L-alanine amidase activity
- Specific function:
- Cell-wall hydrolase probably involved in cell-wall hydrolysis, septation or recycling
- Gene Name:
- amiC
- Uniprot ID:
- P63883
- Molecular weight:
- 45634
Reactions
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. |
- General function:
- Involved in lyase activity
- Specific function:
- Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates
- Gene Name:
- ltaE
- Uniprot ID:
- P75823
- Molecular weight:
- 36494
Reactions
L-threonine = glycine + acetaldehyde. |
L-allo-threonine = glycine + acetaldehyde. |
- General function:
- Defense mechanisms
- Specific function:
- Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. To a lesser extent, can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc-tetrapeptide, GlcNAc-MurNAc-tetrapeptide, and GlcNAc- anhMurNAc-tetrapeptide. Does not act on murein sacculi or cross- linked muropeptides. The tripeptides produced by the lcdA reaction can then be reused as peptidoglycan building blocks; lcdA is thereby involved in murein recycling. Is also essential for viability during stationary phase
- Gene Name:
- ldcA
- Uniprot ID:
- P76008
- Molecular weight:
- 33567
Reactions
GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H(2)O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine. |
- General function:
- Involved in metabolic process
- Specific function:
- Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo
- Gene Name:
- sufS
- Uniprot ID:
- P77444
- Molecular weight:
- 44433
Reactions
L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor. |
L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptor. |
- General function:
- Involved in metabolic process
- Specific function:
- Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine. L-cysteine sulfinic acid is the best substrate. Functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate
- Gene Name:
- csdA
- Uniprot ID:
- Q46925
- Molecular weight:
- 43234
- General function:
- Involved in transporter activity
- Specific function:
- Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane
- Gene Name:
- livH
- Uniprot ID:
- P0AEX7
- Molecular weight:
- 32982
- General function:
- Involved in transporter activity
- Specific function:
- Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane
- Gene Name:
- livM
- Uniprot ID:
- P22729
- Molecular weight:
- 46269
- General function:
- Involved in 1-aminocyclopropane-1-carboxylate synthase activity
- Specific function:
- Specific function unknown
- Gene Name:
- yfbQ
- Uniprot ID:
- P0A959
- Molecular weight:
- 45517
Reactions
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate. |
- General function:
- Not Available
- Specific function:
- Participates in cysteine desulfuration mediated by sufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for sufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of sufS, an intermediate product of cysteine desulfuration process. Together with the sufBCD complex, it thereby enhances up to 50- fold, the cysteine desulfurase activity of sufS. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Does not affect the selenocysteine lyase activity of sufS
- Gene Name:
- sufE
- Uniprot ID:
- P76194
- Molecular weight:
- 15800
- General function:
- Involved in nucleotide binding
- Specific function:
- Component of the leucine-specific transport system
- Gene Name:
- livG
- Uniprot ID:
- P0A9S7
- Molecular weight:
- 28427
- General function:
- Involved in amino acid transport
- Specific function:
- This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids
- Gene Name:
- livJ
- Uniprot ID:
- P0AD96
- Molecular weight:
- 39076
- General function:
- Involved in nucleotide binding
- Specific function:
- Component of the leucine-specific transport system
- Gene Name:
- livF
- Uniprot ID:
- P22731
- Molecular weight:
- 26310
- General function:
- Amino acid transport and metabolism
- Specific function:
- Specific function unknown
- Gene Name:
- yfdZ
- Uniprot ID:
- P77434
- Molecular weight:
- 46216
Reactions
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate. |
Transporters
- General function:
- Involved in sodium:amino acid symporter activity
- Specific function:
- Specific function unknown
- Gene Name:
- yaaJ
- Uniprot ID:
- P30143
- Molecular weight:
- 51662
- General function:
- Involved in nucleotide binding
- Specific function:
- Probably part of a binding-protein-dependent transport system yecCS for an amino acid. Probably responsible for energy coupling to the transport system
- Gene Name:
- yecC
- Uniprot ID:
- P37774
- Molecular weight:
- 27677
- General function:
- Involved in transporter activity
- Specific function:
- Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane
- Gene Name:
- yecS
- Uniprot ID:
- P0AFT2
- Molecular weight:
- 24801
- General function:
- Involved in transport
- Specific function:
- Permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine
- Gene Name:
- cycA
- Uniprot ID:
- P0AAE0
- Molecular weight:
- 51659
- General function:
- Involved in transporter activity
- Specific function:
- Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane
- Gene Name:
- livH
- Uniprot ID:
- P0AEX7
- Molecular weight:
- 32982
- General function:
- Involved in transporter activity
- Specific function:
- Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane
- Gene Name:
- livM
- Uniprot ID:
- P22729
- Molecular weight:
- 46269
- General function:
- Involved in transporter activity
- Specific function:
- Non-specific porin
- Gene Name:
- ompN
- Uniprot ID:
- P77747
- Molecular weight:
- 41220
- General function:
- Involved in transporter activity
- Specific function:
- Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes
- Gene Name:
- phoE
- Uniprot ID:
- P02932
- Molecular weight:
- 38922
- General function:
- Involved in nucleotide binding
- Specific function:
- Component of the leucine-specific transport system
- Gene Name:
- livG
- Uniprot ID:
- P0A9S7
- Molecular weight:
- 28427
- General function:
- Involved in amino acid transport
- Specific function:
- This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids
- Gene Name:
- livJ
- Uniprot ID:
- P0AD96
- Molecular weight:
- 39076
- General function:
- Involved in nucleotide binding
- Specific function:
- Component of the leucine-specific transport system
- Gene Name:
- livF
- Uniprot ID:
- P22731
- Molecular weight:
- 26310
- General function:
- Involved in transporter activity
- Specific function:
- OmpF is a porin that forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. It is also a receptor for the bacteriophage T2
- Gene Name:
- ompF
- Uniprot ID:
- P02931
- Molecular weight:
- 39333
- General function:
- Involved in transporter activity
- Specific function:
- Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane
- Gene Name:
- ompC
- Uniprot ID:
- P06996
- Molecular weight:
- 40368