L-fuculokinase (P11553)

Identification
Name:L-fuculokinase
Synonyms:
  • L-fuculose kinase
Gene Name:fucK
Enzyme Class:
Biological Properties
General Function:Involved in phosphotransferase activity, alcohol group as acceptor
Specific Function:ATP + L-fuculose = ADP + L-fuculose 1- phosphate
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
  • Fructose and mannose metabolism ec00051
  • Microbial metabolism in diverse environments ec01120
KEGG Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Fuculose ↔ 1.0ADP + 1.0L-Fuculose 1-phosphate + 1.0Hydrogen ion
ReactionCard
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Fuculose ↔ 1.0ADP + 1.0L-Fuculose 1-phosphate
ReactionCard
SMPDB Reactions:
1.0Thumb+1.0keto-L-rhamnulose → 1.0L-fuculose 1-phosphate+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0keto-L-rhamnulose → 1.0L-fuculose 1-phosphate + 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0L-Fuculose 1-phosphate + 1.0ADP
ReactionCard
1.0D-Ribulose+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb
1.0D-Ribulose + 1.0Adenosine triphosphate + 1.0D-Ribulose → 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0D-Ribulose-1-phosphate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0D-Ribulose + 1.0Adenosine triphosphate → 1.0D-Ribulose-1-phosphate + 1.0Adenosine monophosphate + 1.0Hydrogen ion
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Fuculose ↔ 1.0ADP + 1.0L-Fuculose 1-phosphate + 1.0Hydrogen ion
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0D-Ribulose + 1.0Adenosine triphosphate → 1.0Hydrogen ion + 1.0D-Ribulose-1-phosphate + 1.0ADP
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0L-Fuculose + 1.0Adenosine triphosphate → 1.0Hydrogen ion + 1.0L-Fuculose 1-phosphate + 1.0ADP
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0L-Fuculose → 1.0ADP + 1.0L-Fuculose 1-phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00045Adenosine monophosphateMetaboCard
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB00621D-RibuloseMetaboCard
ECMDB20544D-Ribulose-1-phosphateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB04069L-FuculoseMetaboCard
ECMDB20165L-Fuculose 1-phosphateMetaboCard
GO Classification:
Function
catalytic activity
L-fuculokinase activity
phosphotransferase activity, alcohol group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Blattner:b2803
Gene OrientationClockwise
Centisome Percentage:63.27
Left Sequence End2935460
Right Sequence End2936908
Gene Sequence:
>1449 bp
ATGAAGTTTATCATTAAATTGTTCCCGGAAATCACCATCAAAAGCCAATCTGTGCGCTTG
CGCTTTATAAAAATCCTTACCGGGAACATTCGTAACGTTTTAAAGCACTATGATGAGACG
CTCGCTGTCGTCCGCCACTGGGATAACATCGAAGTTCGCGCAAAAGATGAAAACCAGCGT
CTGGCTATTCGCGACGCTCTGACCCGTATTCCGGGTATCCACCATATTCTCGAAGTCGAA
GACGTGCCGTTTACCGACATGCACGATATTTTCGAGAAAGCGTTGGTTCAGTATCGCGAT
CAGCTGGAAGGCAAAACCTTCTGCGTACGCGTGAAGCGCCGTGGCAAACATGATTTTAGC
TCGATTGATGTGGAACGTTACGTCGGCGGCGGTTTAAATCAGCATATTGAATCCGCGCGC
GTGAAGCTGACCAATCCGGATGTGACTGTCCATCTGGAAGTGGAAGACGATCGTCTCCTG
CTGATTAAAGGCCGCTACGAAGGTATTGGCGGTTTCCCGATCGGCACCCAGGAAGATGTG
CTGTCGCTCATTTCCGGTGGTTTCGACTCCGGTGTTTCCAGTTATATGTTGATGCGTCGC
GGCTGCCGCGTGCATTACTGCTTCTTTAACCTCGGCGGCGCGGCGCATGAAATTGGCGTG
CGTCAGGTGGCGCATTATCTGTGGAACCGCTTTGGCAGCTCCCACCGCGTGCGTTTTGTC
GCTATTAATTTCGAACCGGTCGTCGGGGAAATTCTCGAGAAAATCGACGACGGTCAGATG
GGCGTTATCCTCAAACGTATGATGGTGCGTGCCGCATCTAAAGTGGCTGAACGTTACGGC
GTACAGGCGCTGGTCACCGGCGAAGCGCTCGGCCAGGTGTCCAGCCAGACGCTGACCAAC
CTGCGCCTGATTGATAACGTCTCCGACACGCTGATCCTGCGTCCGCTGATCTCTTACGAC
AAAGAGCACATCATCAACCTGGCCCGCCAGATTGGCACCGAAGACTTTGCTCGCACGATG
CCGGAATATTGTGGTGTGATCTCCAAAAGCCCGACGGTGAAAGCAGTTAAATCGAAGATT
GAAGCGGAAGAAGAGAAGTTCGACTTCAGCATTCTCGATAAAGTGGTTGAGGAAGCGAAT
AACGTTGATATCCGCGAAATCGCCCAGCAGACCGAGCAGGAAGTGGTGGAAGTGGAAACC
GTCAATGGCTTCGGCCCGAACGACGTGATCCTCGATATCCGTTCTATCGATGAACAGGAA
GATAAGCCACTGAAAGTCGAAGGGATTGATGTGGTTTCTCTGCCGTTCTATAAACTGAGC
ACCAAATTTGGCGATCTCGACCAGAACAAAACCTGGCTGCTGTGGTGTGAGCGCGGGGTG
ATGAGCCGTCTGCAGGCGCTCTATCTGCGCGAGCAGGGCTTTAACAATGTGAAGGTATAT
CGCCCGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:482
Protein Molecular Weight:53235
Protein Theoretical pI:5
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>L-fuculokinase
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENNTWHQWS
LDAILQRFADCCRQINSELTECHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAV
MDNIERLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFISSLINHRLTG
EFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELD
SQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQN
AGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKASELLLVGGGSRNTLWNQI
KANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQYRYFYPQTEPEFIE
EV
References
External Links:
ResourceLink
Uniprot ID:P11553
Uniprot Name:FUCK_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674563
Ecogene ID:EG10350
Ecocyc:EG10350
ColiBase:b2803
Kegg Gene:b2803
EchoBASE ID:EB0346
CCDB:FUCK_ECOLI
BacMap:16130710
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Lu, Z., Lin, E. C. (1989). "The nucleotide sequence of Escherichia coli genes for L-fucose dissimilation." Nucleic Acids Res 17:4883-4884. Pubmed: 2664711