Heme exporter protein D (P0ABM5)

Identification
Name:Heme exporter protein D
Synonyms:
  • Cytochrome c-type biogenesis protein CcmD
Gene Name:ccmD
Enzyme Class:Not Available
Biological Properties
General Function:Involved in transport
Specific Function:Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (Potential)
Cellular Location:Cell inner membrane; Single-pass membrane protein (Potential)
SMPDB Pathways:Not Available
KEGG Pathways:
EcoCyc Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Heme → 1.0ADP + 1.0Hydrogen ion + 1.0Phosphate + 1.0Heme
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB03178HemeMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB01429PhosphateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Process
establishment of localization
transport
Gene Properties
Blattner:b2198
Gene OrientationCounterclockwise
Centisome Percentage:49.43
Left Sequence End2293399
Right Sequence End2293608
Gene Sequence:
>210 bp
ATGTCTAAGATTAAAGGTAACGTTAAGTGGTTTAATGAGTCCAAAGGATTCGGTTTCATT
ACTCCGGAAGACGGCAGCAAAGACGTGTTCGTACACTTCTCTGCAATCCAGACTAATGGT
TTTAAAACTCTTGCTGAAGGTCAGCGCGTAGAGTTCGAAATCACTAACGGTGCCAAAGGC
CCTTCTGCTGCAAACGTAATCGCTCTGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:69
Protein Molecular Weight:7745
Protein Theoretical pI:12
Signaling Regions:
  • None
Transmembrane Regions:
  • 18-37
Protein Sequence:
>Heme exporter protein D
MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARL
RAAQQQEAA
References
External Links:
ResourceLink
Uniprot ID:P0ABM5
Uniprot Name:CCMD_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1651256
Ecogene ID:EG12169
Ecocyc:EG12169
ColiBase:b2198
Kegg Gene:b2198
EchoBASE ID:EB2088
CCDB:CCMD_ECOLI
BacMap:16130135
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Thony-Meyer, L., Fischer, F., Kunzler, P., Ritz, D., Hennecke, H. (1995). "Escherichia coli genes required for cytochrome c maturation." J Bacteriol 177:4321-4326. Pubmed: 7635817