Cytochrome c-type protein napC (P0ABL5)

Identification
Name:Cytochrome c-type protein napC
Synonyms:Not Available
Gene Name:napC
Enzyme Class:Not Available
Biological Properties
General Function:Involved in heme binding
Specific Function:Mediates electron flow from quinones to the napAB complex
Cellular Location:Cell inner membrane; Single-pass membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
KEGG Reactions:
1.0Thumb+1.0Acceptor+1.0Thumb+1.0Acceptor ↔ 1.0Thumb+1.0Reduced acceptor+1.0Reduced acceptor
1.0Nitrite + 1.0Acceptor + 1.0Water + 1.0Acceptor ↔ 1.0Nitrate + 1.0Reduced acceptor + 1.0Reduced acceptor
ReactionCard
Complex Reactions:
2.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+2.0Thumb
2.0Hydrogen ion + 1.0Nitrate + 1.0Ubiquinol-8 → 1.0Water + 1.0Nitrite + 1.0Ubiquinone-8 + 2.0Hydrogen ion
ReactionCard
2.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Menaquinone 8+1.0Thumb+2.0Thumb
2.0Hydrogen ion + 1.0Menaquinol 8 + 1.0Nitrate → 1.0Water + 1.0Menaquinone 8 + 1.0Nitrite + 2.0Hydrogen ion
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Ubiquinol-8 + 1.0Nitrate → 1.0Ubiquinone-8 + 1.0Water + 1.0Nitrite
ReactionCard
1.0Thumb+1.0Thumb → 1.0Menaquinone 8+1.0Thumb+1.0Thumb
1.0Menaquinol 8 + 1.0Nitrate → 1.0Menaquinone 8 + 1.0Water + 1.0Nitrite
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21225Hydrogen ionMetaboCard
ECMDB21245Menaquinol 8MetaboCard
ECMDB02878NitrateMetaboCard
ECMDB02786NitriteMetaboCard
ECMDB01060Ubiquinol-8MetaboCard
ECMDB21296Ubiquinone-8MetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Component
cell part
integral to membrane
intrinsic to membrane
membrane part
Function
binding
cation binding
heme binding
ion binding
iron ion binding
metal ion binding
transition metal ion binding
Gene Properties
Blattner:b2202
Gene OrientationCounterclockwise
Centisome Percentage:49.48
Left Sequence End2295679
Right Sequence End2296281
Gene Sequence:
>603 bp
GTGAATATTAATTACCCTGCTGAATATGAAATTGGAGATATCGTCTTTACATGTATAGGT
GCTGCCTTATTTGGTCAAATATCAGCTGCATCAAATTGCTGGAGTAATCACGTCGGGATC
ATTATCGGTCATAACGGTGAAGACTTCCTGGTTGCAGAAAGCCGGGTTCCCCTTTCAACC
ATCACCACGCTATCTCGTTTTATTAAACGTTCGTCTAATCAACGCTATGCTATAAAGCGA
TTAGACGCTGGGCTGACAGAACGACAAAAACAACGAATTGTTGAACAGGTTCCCTCCCGG
CTACGCAAACTTTACCACACCGGTTTTAAATACGAATCTTCGCGCCAGTTCTGTTCAAAA
TTTGTTTTTGATATTTATAAAGAAGCGCTATGTATTCCGGTGGGTGAAATAGAGACGTTT
GGAGAATTGTTAAATAGCAATCCGAATGCAAAACTCACTTTCTGGAAATTCTGGTTCCTG
GGTTCTATTCCGTGGGAGCGTAAAACCGTCACGCCAGCCAGTTTGTGGCATCATCCGGGT
TTGGTGTTGATTCATGCGGAGGGAGTGGAAACGCCTCAGCCGGAACTGACCGAGGCGGTA
TAA
Protein Properties
Pfam Domain Function:
Protein Residues:200
Protein Molecular Weight:23100
Protein Theoretical pI:9
Signaling Regions:
  • None
Transmembrane Regions:
  • 24-44
Protein Sequence:
>Cytochrome c-type protein napC
MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGFNTGMEKANTEEFCISC
HEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIRKLKASKELYGKIFGVIDT
PQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTAQKSVAAKMHDQAVKDGQTCI
DCHKGIAHKLPDMREVEPGF
References
External Links:
ResourceLink
Uniprot ID:P0ABL5
Uniprot Name:NAPC_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85675152
Ecogene ID:EG12060
Ecocyc:EG12060
ColiBase:b2202
Kegg Gene:b2202
EchoBASE ID:EB1990
CCDB:NAPC_ECOLI
BacMap:16130139
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Iobbi-Nivol, C., Crooke, H., Griffiths, L., Grove, J., Hussain, H., Pommier, J., Mejean, V., Cole, J. A. (1994). "A reassessment of the range of c-type cytochromes synthesized by Escherichia coli K-12." FEMS Microbiol Lett 119:89-94. Pubmed: 8039676