Uncharacterized oxidoreductase yihU (P0A9V8)

Identification
Name:Uncharacterized oxidoreductase yihU
Synonyms:Not Available
Gene Name:yihU
Enzyme Class:
Biological Properties
General Function:Involved in 3-hydroxyisobutyrate dehydrogenase activity
Specific Function:Specific function unknown
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb+1.0Thumb
1.04-Hydroxybutanoic acid + 1.0NAD ↔ 1.0Succinic acid semialdehyde + 1.0NADH + 1.0Hydrogen ion
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Hydrogen ion + 1.0NADH + 1.0Succinic acid semialdehyde ↔ 1.0gamma-Hydroxybutyrate + 1.0NAD
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB239052-Hydroxy-3-oxopropane-1-sulfonateMetaboCard
ECMDB238214-Hydroxybutanoic acidMetaboCard
ECMDB21338gamma-HydroxybutyrateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB00902NADMetaboCard
ECMDB01487NADHMetaboCard
ECMDB01259Succinic acid semialdehydeMetaboCard
GO Classification:
Function
3-hydroxyisobutyrate dehydrogenase activity
binding
catalytic activity
coenzyme binding
cofactor binding
oxidoreductase activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
phosphogluconate dehydrogenase (decarboxylating) activity
Process
alcohol metabolic process
branched chain family amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
cellular metabolic process
glucose catabolic process
glucose metabolic process
hexose metabolic process
metabolic process
monosaccharide metabolic process
oxidation reduction
pentose-phosphate shunt
small molecule metabolic process
valine metabolic process
Gene Properties
Blattner:b3882
Gene OrientationCounterclockwise
Centisome Percentage:87.74
Left Sequence End4070698
Right Sequence End4071594
Gene Sequence:
>897 bp
ATGCTGGAAAAATCTCTGGCAACACTTTTCGCGTTGTTAATTTTAGCAACGCTGATAAAC
CGTTTTCTGCTATGGCGGTTACCGGAGAGAAAAGGGGGTGAGGTTACATTACGTATTCGT
ACCTGGTGGGGCATCGTCATTTGTTTTTCAATGGTGATTTCAGGTCCACGCTGGATGACG
TTGACGTTTTTTGCGCTGATAAGTTTTCTGGCATTGAAAGAATATTGTACGCTTATATCT
GTACATTTTCCGCGTTGGTTATATTGGGGTATTCCTCTTAACTATTTGCTTATCGGTTTT
AATTGCTTTGAGCTGTTTCTGTTATTTATACCTTTGGCTGGGTTTCTGATATTAGCCACC
GGGCAAGTTTTAGTGGGTGACCCCTCTGGTTTTCTGCATACCGTGAGCGCCATTTTTTGG
GGCTGGATAATGACCGTTTTCGCCTTGAGTCATGCCGCCTGGTTATTAATGTTGCCAACC
ACAAATATCCAGGGCGGGGCGTTACTGGTGTTATTTCTTTTGGCATTAACCGAGTCAAAC
GATATTGCACAGTATTTATGGGGAAAATCCTGCGGCAGAAGAAAAGTGGTCCCTAAAGTC
AGCCCGGGAAAAACATTGGAAGGTCTGATGGGCGGCGTCATCACCATCATGATTGCGTCA
CTGATTATCGGACCGTTACTGACACCGCTAAATACATTACAGGCATTATTAGCGGGTTTG
TTAATTGGTATTAGTGGTTTTTGCGGCGATGTCGTGATGTCAGCCATCAAACGAGATATT
GGTGTTAAAGATAGCGGAAAACTATTGCCAGGACATGGCGGACTCCTTGACAGGATTGAC
TCATTAATTTTCACCGCTCCGGTATTTTTTTATTTTATACGCTACTGCTGTTACTGA
Protein Properties
Pfam Domain Function:
Protein Residues:298
Protein Molecular Weight:31158
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Uncharacterized oxidoreductase yihU
MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKGATPAANPAQAAKDAEF
IITMLPNGDLVRNVLFGENGVCEGLSTDALVIDMSTIHPLQTDKLIADMQAKGFSMMDVP
VGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELINAGGPGMGIRVKLINNYMSIA
LNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTTSWPNKVLSGDLSPAFMIDLAHK
DLGIALDVANQLHVPMPLGAASREVYSQARAAGRGRQDWSAILEQVRVSAGMTAKVKM
References
External Links:
ResourceLink
Uniprot ID:P0A9V8
Uniprot Name:YIHU_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674949
Ecogene ID:EG11847
Ecocyc:EG11847
ColiBase:b3882
Kegg Gene:b3882
EchoBASE ID:EB1793
CCDB:YIHU_ECOLI
BacMap:16131722
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Plunkett, G. 3rd, Burland, V., Daniels, D. L., Blattner, F. R. (1993). "Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes." Nucleic Acids Res 21:3391-3398. Pubmed: 8346018