ECMDB: Taurine-binding periplasmic protein (Q47537)

Identification

Name:

Taurine-binding periplasmic protein

Synonyms:

Sulfate starvation-induced protein 1
SSI1

Gene Name:

tauA

Enzyme Class:

Not Available

Biological Properties

General Function:

Involved in transporter activity

Specific Function:

Part of a binding-protein-dependent transport system for taurine

Cellular Location:

Periplasm (Potential)

SMPDB Pathways:

Sulfur metabolism PW000922
Taurine Metabolism PW000774
Taurine Metabolism I PW001028
inner membrane transport PW000786
sulfur metabolism (butanesulfonate) PW000923
sulfur metabolism (ethanesulfonate) PW000925
sulfur metabolism (isethionate) PW000926
sulfur metabolism (methanesulfonate) PW000927
sulfur metabolism (propanesulfonate) PW000924

KEGG Pathways:

Sulfur metabolism ec00920

Transports:

Taurine

Transport References:

Not Available

SMPDB Reactions:

1.0

→

1.0

1.0Adenosine diphosphate

1.0

1.0Taurine + 1.0Adenosine triphosphate + 1.0Water → 1.0Taurine + 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0ADP
ReactionCard

EcoCyc Reactions:

1.0

→

1.0

1.0Adenosine triphosphate + 1.0Water + 1.0Taurine → 1.0ADP + 1.0Hydrogen ion + 1.0Phosphate + 1.0Taurine
ReactionCard

Complex Reactions:

1.0

→

1.0

1.0Adenosine triphosphate + 1.0Water + 1.0Isethionic acid → 1.0ADP + 1.0Hydrogen ion + 1.0Isethionic acid + 1.0Phosphate
ReactionCard

1.0

→

1.0

1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0ADP + 1.0Butanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
ReactionCard

Metabolites:

ECMDB ID	Name	View
ECMDB00538	Adenosine triphosphate	MetaboCard
ECMDB01341	ADP	MetaboCard
ECMDB21313	Butanesulfonate	MetaboCard
ECMDB21225	Hydrogen ion	MetaboCard
ECMDB21233	Isethionic acid	MetaboCard
ECMDB01429	Phosphate	MetaboCard
ECMDB00251	Taurine	MetaboCard
ECMDB00494	Water	MetaboCard

GO Classification:

Component
cell part
outer membrane-bounded periplasmic space
periplasmic space
Function
binding
transporter activity
Process
establishment of localization
transport

Gene Properties

Blattner:

b0365

Gene Orientation

Clockwise

Centisome Percentage:

8.29

Left Sequence End

384456

Right Sequence End

385418

Gene Sequence:

>963 bp
ATGGCAATTTCATCGCGTAACACACTTCTTGCCGCACTGGCATTCATCGCTTTTCAGGCA
CAGGCGGTGAACGTCACCGTGGCGTATCAAACCTCAGCCGAACCGGCGAAAGTGGCTCAG
GCCGACAACACCTTTGCTAAAGAAAGCGGAGCAACCGTGGACTGGCGTAAGTTTGACAGC
GGAGCCAGCATCGTGCGGGCGCTGGCTTCAGGCGACGTGCAAATCGGCAACCTCGGTTCC
AGCCCGTTAGCGGTTGCAGCCAGCCAACAGGTGCCGATTGAAGTCTTCTTGCTGGCGTCA
AAACTGGGTAACTCCGAAGCGCTGGTGGTAAAGAAAACTATCAGCAAACCGGAAGATCTG
ATTGGCAAACGCATCGCCGTACCGTTTATCTCCACCACCCACTACAGCCTGCTGGCGGCA
CTGAAACACTGGGGCATTAAACCCGGGCAAGTGGAGATTGTGAACCTGCAGCCGCCCGCG
ATTATCGCTGCCTGGCAGCGGGGAGATATTGATGGTGCTTATGTCTGGGCACCGGCGGTT
AACGCCCTGGAAAAAGACGGCAAGGTGTTGACCGATTCTGAACAGGTCGGGCAGTGGGGC
GCGCCAACGCTGGACGTCTGGGTGGTGCGCAAAGATTTTGCCGAGAAACATCCTGAGGTC
GTGAAAGCGTTCGCTAAAAGCGCCATCGATGCTCAGCAACCGTACATTGCTAACCCAGAC
GTGTGGCTGAAACAGCCGGAAAACATCAGCAAACTGGCGCGTTTAAGCGGCGTGCCTGAA
GGTGACGTTCCGGGGCTGGTGAAGGGGAATACCTATCTGACGCCGCAGCAACAAACGGCA
GAACTGACCGGACCGGTGAACAAAGCGATCATCGACACCGCGCAGTTTTTGAAAGAGCAG
GGCAAGGTCCCGGCTGTAGCGAATGATTACAGCCAGTACGTTACCTCGCGCTTCGTGCAA
TAA

Protein Properties

Pfam Domain Function:

OpuAC (PF04069 )

Protein Residues:

320

Protein Molecular Weight:

34266

Protein Theoretical pI:

Signaling Regions:

1-22

Transmembrane Regions:

None

Protein Sequence:

>Taurine-binding periplasmic protein
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDS
GASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDL
IGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAV
NALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPD
VWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQ
GKVPAVANDYSQYVTSRFVQ

References

External Links:

Resource	Link
Uniprot ID:	Q47537
Uniprot Name:	TAUA_ECOLI
GenBank Gene ID:	AP009048
Genebank Protein ID:	85674506
Ecogene ID:	EG13300
Ecocyc:	EG13300
ColiBase:	b0365
Kegg Gene:	b0365
EchoBASE ID:	EB3085
CCDB:	TAUA_ECOLI
BacMap:	90111122

General Reference:

Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
Quadroni, M., Staudenmann, W., Kertesz, M., James, P. (1996). "Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli." Eur J Biochem 239:773-781. Pubmed: 8774726
van der Ploeg, J. R., Weiss, M. A., Saller, E., Nashimoto, H., Saito, N., Kertesz, M. A., Leisinger, T. (1996). "Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source." J Bacteriol 178:5438-5446. Pubmed: 8808933