Putative aliphatic sulfonates-binding protein (P75853)

Identification
Name:Putative aliphatic sulfonates-binding protein
Synonyms:Not Available
Gene Name:ssuA
Enzyme Class:Not Available
Biological Properties
General Function:Involved in sulfur compound metabolic process
Specific Function:Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein
Cellular Location:Periplasm (Potential)
SMPDB Pathways:
KEGG Pathways:
Transports:
    Transport References:Not Available
    SMPDB Reactions:
    1.0Alkyl Sulfate+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Alkyl Sulfate+1.0Thumb
    1.0Alkyl Sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Alkyl Sulfate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Butanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.03-(N-morpholino)propanesulfonate → 1.0Phosphate + 1.0Hydrogen ion + 1.0Adenosine diphosphate + 1.03-(N-morpholino)propanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0 ethanesulfonate → 1.0Hydrogen ion + 1.0Phosphate + 1.0Adenosine diphosphate + 1.0 ethanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0 isethionate → 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0Phosphate + 1.0 isethionate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0methanesulfonate + 1.0Methanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0methanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Cysteine-S-sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Cysteine-S-sulfate + 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0ADP
    ReactionCard
    Complex Reactions:
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Isethionic acid → 1.0ADP + 1.0Hydrogen ion + 1.0Isethionic acid + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0ADP + 1.0Butanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Ethanesulfonate → 1.0ADP + 1.0Ethanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Methanesulfonate → 1.0ADP + 1.0Hydrogen ion + 1.0Methanesulfonate + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Sulfoacetate → 1.0ADP + 1.0Hydrogen ion + 1.0Phosphate + 1.0Sulfoacetate
    ReactionCard
    Metabolites:
    ECMDB IDNameView
    ECMDB24254 ethanesulfonateMetaboCard
    ECMDB24255 isethionateMetaboCard
    ECMDB242533-(N-morpholino)propanesulfonateMetaboCard
    ECMDB00538Adenosine triphosphateMetaboCard
    ECMDB01341ADPMetaboCard
    ECMDB21313ButanesulfonateMetaboCard
    ECMDB00731Cysteine-S-sulfateMetaboCard
    ECMDB21330EthanesulfonateMetaboCard
    ECMDB21225Hydrogen ionMetaboCard
    ECMDB21233Isethionic acidMetaboCard
    ECMDB21344MethanesulfonateMetaboCard
    ECMDB01429PhosphateMetaboCard
    ECMDB21358SulfoacetateMetaboCard
    ECMDB00494WaterMetaboCard
    GO Classification:
    Component
    cell part
    membrane
    outer membrane-bounded periplasmic space
    periplasmic space
    Function
    transporter activity
    Process
    cellular metabolic process
    establishment of localization
    metabolic process
    sulfur metabolic process
    transport
    Gene Properties
    Blattner:b0936
    Gene OrientationCounterclockwise
    Centisome Percentage:21.45
    Left Sequence End995208
    Right Sequence End996167
    Gene Sequence:
    >960 bp
ATGCGTAACATCATTAAACTGGCGCTGGCGGGATTGCTTAGCGTCTCTACTTTTGCGGTT
GCTGCAGAATCCTCGCCTGAAGCGTTACGTATAGGCTATCAGAAAGGCAGTATTGGTATG
GTGCTGGCAAAAAGCCACCAGTTACTGGAAAAACGCTATCCGGAATCAAAAATCTCCTGG
GTGGAGTTCCCCGCGGGTCCGCAAATGTTGGAAGCGTTAAACGTTGGCAGTATTGATCTC
GGCAGTACCGGGGATATTCCGCCAATCTTTGCCCAGGCTGCCGGGGCTGATTTGGTGTAC
GTGGGCGTCGAGCCACCGAAGCCCAAAGCCGAAGTGATTCTGGTGGCAGAAAACAGCCCG
ATCAAAACCGTAGCCGATCTTAAAGGTCACAAAGTTGCCTTTCAGAAAGGTTCCAGTTCA
CACAACCTTTTACTGCGTGCACTGCGTCAGGCCGGACTTAAGTTTACCGATATCCAACCC
ACTTACCTGACGCCCGCTGATGCCCGCGCCGCGTTCCAGCAAGGTAACGTTGACGCCTGG
GCTATCTGGGATCCCTACTACTCTGCTGCATTATTACAGGGCGGCGTGCGGGTGCTGAAA
GACGGCACCGATCTCAATCAAACTGGATCGTTTTATCTGGCAGCTCGTCCCTATGCAGAA
AAAAACGGCGCTTTTATTCAGGGCGTACTGGCAACCTTTAGTGAGGCCGATGCGTTAACC
CGCAGCCAGCGCGAGCAAAGCATCGCTTTACTGGCAAAAACGATGGGCTTACCGGCACCG
GTGATTGCCTCTTACTTAGATCATCGCCCTCCTACCACCATCAAACCGGTTAACGCCGAG
GTTGCCGCCTTACAGCAGCAAACGGCAGATCTGTTTTATGAAAATCGTCTGGTGCCGAAA
AAAGTCGATATTCGCCAGCGCATCTGGCAGCCCACTCAACTGGAAGGAAAACAATTATGA
    Protein Properties
    Pfam Domain Function:
    Protein Residues:319
    Protein Molecular Weight:34557
    Protein Theoretical pI:10
    Signaling Regions:
    • 1-21
    Transmembrane Regions:
    • None
    Protein Sequence:
    >Putative aliphatic sulfonates-binding protein
MRNIIKLALAGLLSVSTFAVAAESSPEALRIGYQKGSIGMVLAKSHQLLEKRYPESKISW
VEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVGVEPPKPKAEVILVAENSP
IKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQPTYLTPADARAAFQQGNVDAW
AIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPYAEKNGAFIQGVLATFSEADALT
RSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKPVNAEVAALQQQTADLFYENRLVPK
KVDIRQRIWQPTQLEGKQL
    References
    External Links:
    ResourceLink
    Uniprot ID:P75853
    Uniprot Name:SSUA_ECOLI
    GenBank Gene ID:AJ237695
    Genebank Protein ID:4583567
    Ecogene ID:EG13707
    Ecocyc:EG13707
    ColiBase:b0936
    Kegg Gene:b0936
    EchoBASE ID:EB3471
    CCDB:SSUA_ECOLI
    BacMap:90111189
    General Reference:
    • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
    • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
    • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
    • van Der Ploeg, J. R., Iwanicka-Nowicka, R., Bykowski, T., Hryniewicz, M. M., Leisinger, T. (1999). "The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl." J Biol Chem 274:29358-29365. Pubmed: 10506196