Glycolate oxidase subunit glcE (P52073)

Identification
Name:Glycolate oxidase subunit glcE
Synonyms:Not Available
Gene Name:glcE
Enzyme Class:Not Available
Biological Properties
General Function:Involved in catalytic activity
Specific Function:Specific function unknown
Cellular Location:Not Available
SMPDB Pathways:
  • glycolate and glyoxylate degradation PW000827
KEGG Pathways:
  • Glyoxylate and dicarboxylate metabolism ec00630
KEGG Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Glycolic acid + 1.0Oxygen ↔ 1.0Glyoxylic acid + 1.0Hydrogen peroxide
ReactionCard
SMPDB Reactions:
1.0Thumb+1.0an oxidized electron-transfer flavoprotein  → 1.0Reduced acceptor+1.0Thumb
1.0Glycolic acid + 1.0an oxidized electron-transfer flavoprotein  → 1.0Reduced acceptor + 1.0Glyoxylic acid
ReactionCard
2.0Thumb+2.0an oxidized electron-transfer flavoprotein  → 2.0Reduced acceptor+2.0Thumb
2.0Glycolic acid + 2.0an oxidized electron-transfer flavoprotein  → 2.0Reduced acceptor + 2.0Glyoxylic acid
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0Glycolic acid + 1.0Ubiquinone-8 → 1.0Glyoxylic acid + 1.0Ubiquinol-8
ReactionCard
1.0Thumb+1.0Menaquinone 8 → 1.0Thumb+1.0Thumb
1.0Glycolic acid + 1.0Menaquinone 8 → 1.0Glyoxylic acid + 1.0Menaquinol 8
ReactionCard
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.02-Demethylmenaquinone 8 + 1.0Glycolic acid → 1.02-Demethylmenaquinol 8 + 1.0Glyoxylic acid
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB211542-Demethylmenaquinol 8MetaboCard
ECMDB211552-Demethylmenaquinone 8MetaboCard
ECMDB23741GlycolateMetaboCard
ECMDB03035Glycolic acidMetaboCard
ECMDB00119Glyoxylic acidMetaboCard
ECMDB21232Hydrogen peroxideMetaboCard
ECMDB21245Menaquinol 8MetaboCard
ECMDB04124OxygenMetaboCard
ECMDB01060Ubiquinol-8MetaboCard
ECMDB21296Ubiquinone-8MetaboCard
GO Classification:
Function
adenyl nucleotide binding
binding
catalytic activity
FAD or FADH2 binding
nucleoside binding
oxidoreductase activity
purine nucleoside binding
Gene Properties
Blattner:b4468
Gene OrientationCounterclockwise
Centisome Percentage:67.32
Left Sequence End3123492
Right Sequence End3124544
Gene Sequence:
>1053 bp
ATGAATTATCAGAACGACGATTTACGCATCAAAGAAATCAAAGAGTTACTTCCTCCTGTC
GCATTGCTGGAAAAATTCCCCGCTACTGAAAATGCCGCGAATACGGTTGCCCATGCCCGA
AAAGCGATCCATAAGATCCTGAAAGGTAATGATGATCGCCTGTTGGTTGTGATTGGCCCA
TGCTCAATTCATGATCCTGTCGCGGCAAAAGAGTATGCCACTCGCTTGCTGGCGCTGCGT
GAAGAGCTGAAAGATGAGCTGGAAATCGTAATGCGCGTCTATTTTGAAAAGCCGCGTACC
ACGGTGGGCTGGAAAGGGCTGATTAACGATCCGCATATGGATAATAGCTTCCAGATCAAC
GACGGTCTGCGTATAGCCCGTAAATTGCTGCTTGATATTAACGACAGCGGTCTGCCAGCG
GCAGGTGAGTTTCTCGATATGATCACCCCACAATATCTCGCTGACCTGATGAGCTGGGGC
GCAATTGGCGCACGTACCACCGAATCGCAGGTGCACCGCGAACTGGCATCAGGGCTTTCT
TGTCCGGTCGGCTTCAAAAATGGCACCGACGGTACGATTAAAGTGGCTATCGATGCCATT
AATGCCGCCGGTGCGCCGCACTGCTTCCTGTCCGTAACGAAATGGGGGCATTCGGCGATT
GTGAATACCAGCGGTAACGGCGATTGCCATATCATTCTGCGCGGCGGTAAAGAGCCTAAC
TACAGCGCGAAGCACGTTGCTGAAGTGAAAGAAGGGCTGAACAAAGCAGGCCTGCCAGCA
CAGGTGATGATCGATTTCAGCCATGCTAACTCGTCCAAACAATTCAAAAAGCAGATGGAT
GTTTGTGCTGACGTTTGCCAGCAGATTGCCGGTGGCGAAAAGGCCATTATTGGCGTGATG
GTGGAAAGCCATCTGGTGGAAGGCAATCAGAGCCTCGAGAGCGGGGAGCCGCTGGCCTAC
GGTAAGAGCATCACCGATGCCTGCATCGGCTGGGAAGATACCGATGCTCTGTTACGTCAA
CTGGCGAATGCAGTAAAAGCGCGTCGCGGGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:350
Protein Molecular Weight:38361
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Glycolate oxidase subunit glcE
MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQTLDVRCHRGIVNYDPTE
LVITARVGTPLVTIEAALESAGQMLPCEPPHYGEEATWGGMVACGLAGPRRPWSGSVRDF
VLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMVGSYGCLGVLTEISMKVLPRPRASLSL
RREISLQEAMSEIAEWQLQPLPISGLCYFDNALWIRLEGGEGSVKAARELLGGEEVAGQF
WQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQLIDWGGALRWLKSTAEDNQIHRIA
RNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQLDPCGVFNPGRMYAEL
References
External Links:
ResourceLink
Uniprot ID:P52073
Uniprot Name:GLCE_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1651339
Ecogene ID:EG12996
Ecocyc:EG12996
ColiBase:b4468
Kegg Gene:b4468
EchoBASE ID:EB2819
CCDB:GLCE_ECOLI
BacMap:49176295
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Pellicer, M. T., Badia, J., Aguilar, J., Baldoma, L. (1996). "glc locus of Escherichia coli: characterization of genes encoding the subunits of glycolate oxidase and the glc regulator protein." J Bacteriol 178:2051-2059. Pubmed: 8606183
  • Riley, M., Abe, T., Arnaud, M. B., Berlyn, M. K., Blattner, F. R., Chaudhuri, R. R., Glasner, J. D., Horiuchi, T., Keseler, I. M., Kosuge, T., Mori, H., Perna, N. T., Plunkett, G. 3rd, Rudd, K. E., Serres, M. H., Thomas, G. H., Thomson, N. R., Wishart, D., Wanner, B. L. (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34:1-9. Pubmed: 16397293