Hydrogen peroxide (ECMDB21232) (M2MDB001640)
Enzymes
- General function:
- Involved in superoxide dismutase activity
- Specific function:
- Destroys radicals which are normally produced within the cells and which are toxic to biological systems
- Gene Name:
- sodA
- Uniprot ID:
- P00448
- Molecular weight:
- 23097
Reactions
2 superoxide + 2 H(+) = O(2) + H(2)O(2). |
- General function:
- Involved in glutathione peroxidase activity
- Specific function:
- Not essential for B12 transport; however, it is an auxiliary component of the transport system
- Gene Name:
- btuE
- Uniprot ID:
- P06610
- Molecular weight:
- 20469
- General function:
- Involved in FMN binding
- Specific function:
- Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Does not use oxygen directly. Is coupled to the respiratory chain
- Gene Name:
- hemG
- Uniprot ID:
- P0ACB4
- Molecular weight:
- 21226
Reactions
Protoporphyrinogen IX + 3 menaquinone = protoporphyrin IX + 3 menaquinol. |
- General function:
- Involved in antioxidant activity
- Specific function:
- 2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH
- Gene Name:
- bcp
- Uniprot ID:
- P0AE52
- Molecular weight:
- 17634
Reactions
2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH. |
- General function:
- Involved in catalytic activity
- Specific function:
- Specific function unknown
- Gene Name:
- glcD
- Uniprot ID:
- P0AEP9
- Molecular weight:
- 53811
- General function:
- Involved in superoxide metabolic process
- Specific function:
- Destroys radicals which are normally produced within the cells and which are toxic to biological systems
- Gene Name:
- sodC
- Uniprot ID:
- P0AGD1
- Molecular weight:
- 17681
Reactions
2 superoxide + 2 H(+) = O(2) + H(2)O(2). |
- General function:
- Involved in superoxide dismutase activity
- Specific function:
- Destroys radicals which are normally produced within the cells and which are toxic to biological systems
- Gene Name:
- sodB
- Uniprot ID:
- P0AGD3
- Molecular weight:
- 21266
Reactions
2 superoxide + 2 H(+) = O(2) + H(2)O(2). |
- General function:
- Involved in electron carrier activity
- Specific function:
- Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin
- Gene Name:
- trxC
- Uniprot ID:
- P0AGG4
- Molecular weight:
- 15555
Reactions
Protein dithiol + NAD(P)(+) = protein disulfide + NAD(P)H. |
- General function:
- Involved in electron carrier activity
- Specific function:
- Catalyzes the oxidation of L-aspartate to iminoaspartate
- Gene Name:
- nadB
- Uniprot ID:
- P10902
- Molecular weight:
- 60337
Reactions
L-aspartate + O(2) = iminosuccinate + H(2)O(2). |
- General function:
- Involved in catalase activity
- Specific function:
- Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity. Displays also NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activity
- Gene Name:
- katG
- Uniprot ID:
- P13029
- Molecular weight:
- 80023
Reactions
Donor + H(2)O(2) = oxidized donor + 2 H(2)O. |
2 H(2)O(2) = O(2) + 2 H(2)O. |
- General function:
- Involved in catalase activity
- Specific function:
- Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
- Gene Name:
- katE
- Uniprot ID:
- P21179
- Molecular weight:
- 84162
Reactions
2 H(2)O(2) = O(2) + 2 H(2)O. |
- General function:
- Involved in adenine deaminase activity
- Specific function:
- Adenine + H(2)O = hypoxanthine + NH(3)
- Gene Name:
- ade
- Uniprot ID:
- P31441
- Molecular weight:
- 63739
Reactions
Adenine + H(2)O = hypoxanthine + NH(3). |
- General function:
- Involved in malate dehydrogenase (quinone) activity
- Specific function:
- (S)-malate + a quinone = oxaloacetate + reduced quinone
- Gene Name:
- mqo
- Uniprot ID:
- P33940
- Molecular weight:
- 60229
Reactions
(S)-malate + a quinone = oxaloacetate + reduced quinone. |
- General function:
- Involved in electron carrier activity
- Specific function:
- 2 ferrocytochrome c + H(2)O(2) = 2 ferricytochrome c + 2 H(2)O
- Gene Name:
- yhjA
- Uniprot ID:
- P37197
- Molecular weight:
- 51570
Reactions
2 ferrocytochrome c + H(2)O(2) = 2 ferricytochrome c + 2 H(2)O. |
- General function:
- Involved in oxidoreductase activity
- Specific function:
- Involved in the breakdown of putrescine via the oxidation of L-glutamylputrescine
- Gene Name:
- puuB
- Uniprot ID:
- P37906
- Molecular weight:
- 47169
Reactions
Gamma-glutamylputrescine + H(2)O + O(2) = Gamma-glutamyl-gamma-aminobutyraldehyde + NH(3) + H(2)O(2). |
- General function:
- Involved in copper ion binding
- Specific function:
- The enzyme prefers aromatic over aliphatic amines
- Gene Name:
- tynA
- Uniprot ID:
- P46883
- Molecular weight:
- 84378
Reactions
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2). |
2-phenylethylamine + H(2)O + O(2) = phenylacetaldehyde + NH(3) + H(2)O(2). |
- General function:
- Involved in iron-sulfur cluster binding
- Specific function:
- Specific function unknown
- Gene Name:
- glcF
- Uniprot ID:
- P52074
- Molecular weight:
- 45110
- General function:
- Involved in catalytic activity
- Specific function:
- Specific function unknown
- Gene Name:
- glcE
- Uniprot ID:
- P52073
- Molecular weight:
- 38361
- General function:
- Involved in oxidoreductase activity
- Specific function:
- Catalyzes the oxidative demethylation of N-methyl-L- tryptophan. Can also use other N-methyl amino acids, including sarcosine, which, however, is a poor substrate
- Gene Name:
- solA
- Uniprot ID:
- P40874
- Molecular weight:
- 40902
Reactions
N-methyl-L-tryptophan + H(2)O + O(2) = L-tryptophan + formaldehyde + H(2)O(2). |
- General function:
- Involved in electron carrier activity
- Specific function:
- Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions
- Gene Name:
- trxA
- Uniprot ID:
- P0AA25
- Molecular weight:
- 11807
- General function:
- Coenzyme transport and metabolism
- Specific function:
- Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
- Gene Name:
- pdxH
- Uniprot ID:
- P0AFI7
- Molecular weight:
- 25545
Reactions
Pyridoxamine 5'-phosphate + H(2)O + O(2) = pyridoxal 5'-phosphate + NH(3) + H(2)O(2). |
Pyridoxine 5'-phosphate + O(2) = pyridoxal 5'-phosphate + H(2)O(2). |
Transporters
- General function:
- Involved in transporter activity
- Specific function:
- Non-specific porin
- Gene Name:
- ompN
- Uniprot ID:
- P77747
- Molecular weight:
- 41220
- General function:
- Involved in transporter activity
- Specific function:
- Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes
- Gene Name:
- phoE
- Uniprot ID:
- P02932
- Molecular weight:
- 38922
- General function:
- Involved in transporter activity
- Specific function:
- OmpF is a porin that forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. It is also a receptor for the bacteriophage T2
- Gene Name:
- ompF
- Uniprot ID:
- P02931
- Molecular weight:
- 39333
- General function:
- Involved in transporter activity
- Specific function:
- Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane
- Gene Name:
- ompC
- Uniprot ID:
- P06996
- Molecular weight:
- 40368