High-affinity zinc uptake system protein znuA (P39172)

Identification
Name:High-affinity zinc uptake system protein znuA
Synonyms:Not Available
Gene Name:znuA
Enzyme Class:Not Available
Biological Properties
General Function:Involved in metal ion binding
Specific Function:Involved in the high-affinity zinc uptake transport system
Cellular Location:Periplasm
SMPDB Pathways:
  • Collection of Reactions without pathways PW001891
KEGG Pathways:
Transports:
    Transport References:Not Available
    EcoCyc Reactions:
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Zinc → 1.0ADP + 1.0Hydrogen ion + 1.0Phosphate + 1.0Zinc
    ReactionCard
    Metabolites:
    ECMDB IDNameView
    ECMDB00538Adenosine triphosphateMetaboCard
    ECMDB01341ADPMetaboCard
    ECMDB21225Hydrogen ionMetaboCard
    ECMDB01429PhosphateMetaboCard
    ECMDB00494WaterMetaboCard
    ECMDB01303ZincMetaboCard
    GO Classification:
    Function
    binding
    cation binding
    ion binding
    metal ion binding
    Process
    cation transport
    cell adhesion
    cellular process
    establishment of localization
    ion transport
    metal ion transport
    transport
    Gene Properties
    Blattner:b1857
    Gene OrientationCounterclockwise
    Centisome Percentage:41.81
    Left Sequence End1939675
    Right Sequence End1940607
    Gene Sequence:
    >933 bp
ATGGTTAAAGTTTATGCCCCGGCTTCCAGTGCCAATATGAGCGTCGGGTTTGATGTGCTC
GGGGCGGCGGTGACACCTGTTGATGGTGCATTGCTCGGAGATGTAGTCACGGTTGAGGCG
GCAGAGACATTCAGTCTCAACAACCTCGGACGCTTTGCCGATAAGCTGCCGTCAGAACCA
CGGGAAAATATCGTTTATCAGTGCTGGGAGCGTTTTTGCCAGGAACTGGGTAAGCAAATT
CCAGTGGCGATGACCCTGGAAAAGAATATGCCGATCGGTTCGGGCTTAGGCTCCAGTGCC
TGTTCGGTGGTCGCGGCGCTGATGGCGATGAATGAACACTGCGGCAAGCCGCTTAATGAC
ACTCGTTTGCTGGCTTTGATGGGCGAGCTGGAAGGCCGTATCTCCGGCAGCATTCATTAC
GACAACGTGGCACCGTGTTTTCTCGGTGGTATGCAGTTGATGATCGAAGAAAACGACATC
ATCAGCCAGCAAGTGCCAGGGTTTGATGAGTGGCTGTGGGTGCTGGCGTATCCGGGGATT
AAAGTCTCGACGGCAGAAGCCAGGGCTATTTTACCGGCGCAGTATCGCCGCCAGGATTGC
ATTGCGCACGGGCGACATCTGGCAGGCTTCATTCACGCCTGCTATTCCCGTCAGCCTGAG
CTTGCCGCGAAGCTGATGAAAGATGTTATCGCTGAACCCTACCGTGAACGGTTACTGCCA
GGCTTCCGGCAGGCGCGGCAGGCGGTCGCGGAAATCGGCGCGGTAGCGAGCGGTATCTCC
GGCTCCGGCCCGACCTTGTTCGCTCTGTGTGACAAGCCGGAAACCGCCCAGCGCGTTGCC
GACTGGTTGGGTAAGAACTACCTGCAAAATCAGGAAGGTTTTGTTCATATTTGCCGGCTG
GATACGGCGGGCGCACGAGTACTGGAAAACTAA
    Protein Properties
    Pfam Domain Function:
    Protein Residues:310
    Protein Molecular Weight:33777
    Protein Theoretical pI:6
    Signaling Regions:
    • 1-26
    Transmembrane Regions:
    • None
    Protein Sequence:
    >High-affinity zinc uptake system protein znuA
MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEH
DYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPGAKQVTIAQLEDVKPLLMKSIHG
DDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHGKLVELMPQSRAKLDANLKDF
EAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHE
IRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLSQLA
NQYASCLKGD
    References
    External Links:
    ResourceLink
    Uniprot ID:P39172
    Uniprot Name:ZNUA_ECOLI
    GenBank Gene ID:AP009048
    Genebank Protein ID:85674277
    Ecogene ID:EG12678
    Ecocyc:EG12678
    ColiBase:b1857
    Kegg Gene:b1857
    EchoBASE ID:EB2543
    CCDB:ZNUA_ECOLI
    BacMap:90111346
    General Reference:
    • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
    • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
    • Itoh, T., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Kasai, H., Kimura, S., Kitakawa, M., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomura, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Seki, Y., Horiuchi, T., et, a. l. .. (1996). "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map." DNA Res 3:379-392. Pubmed: 9097040
    • Link, A. J., Robison, K., Church, G. M. (1997). "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." Electrophoresis 18:1259-1313. Pubmed: 9298646
    • Patzer, S. I., Hantke, K. (1998). "The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli." Mol Microbiol 28:1199-1210. Pubmed: 9680209
    • Wilkins, M. R., Gasteiger, E., Tonella, L., Ou, K., Tyler, M., Sanchez, J. C., Gooley, A. A., Walsh, B. J., Bairoch, A., Appel, R. D., Williams, K. L., Hochstrasser, D. F. (1998). "Protein identification with N and C-terminal sequence tags in proteome projects." J Mol Biol 278:599-608. Pubmed: 9600841