| Identification |
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| Name: | 2-octaprenylphenol hydroxylase |
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| Synonyms: | Not Available |
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| Gene Name: | ubiI |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | ubiquinone biosynthetic process |
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| Specific Function: | FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | - Secondary Metabolites: Ubiquinol biosynthesis PW000981
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| KEGG Pathways: | - Ubiquinone and other terpenoid-quinone biosynthesis ec00130
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| SMPDB Reactions: | |
1.0 | + | 1.0 | + | 1.0NADPH | + | 1.0 | + | 1.0 | → | 1.0 | + | 1.0 | + | 1.02-Octaprenyl-6-hydroxyphenol | + | 1.0 |
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| Metabolites: | |
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| GO Classification: | | Function |
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| 2-octaprenylphenol hydroxylase activity | | flavin adenine dinucleotide binding | | monooxygenase activity | | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | | secondary metabolite biosynthetic process | | ubiquinone biosynthetic process |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1203
atgcaaagtgttgatgtagccattgttggcggcggcatggtggggctggcggttgcctgt
ggcttacaggggagcggcttacgcgttgccgtactggagcagcgcgtacaggaacctctg
gcggcgaatgcaccaccacaactgcgcgtttcggctatcaatgccgccagcgaaaaatta
ctcacccgtcttggcgtctggcaggacattctctctcgtagggccagctgttatcacggt
atggaagtgtgggacaaagacagctttggtcacatttcgtttgacgatcaaagcatgggc
tatagccatcttgggcatatcgttgaaaattcagtgattcactacgcgctgtggaacaaa
gcgcatcagtcgtcagatatcactctgttagcccccgcagaattacagcaggtcgcctgg
ggagaaaatgaaaccttcctgacgctgaaagatggcagcatgttaacggcgcgtctggtg
attggcgcggacggcgctaattcctggttgcgcaacaaagccgatattccgctgactttc
tgggattatcagcatcacgcgctggtagcgaccattcgcacggaagaaccgcatgatgcg
gtggcgcggcaggttttccatggcgaaggcattctggcctttttaccgcttagcgatccg
catctttgctcgattgtctggtcactgtcgccagaggaagcgcagcggatgcagcaggca
agtgaagacgaatttaatcgcgcgttaaatatcgcttttgataatcgcctgggcttatgc
aaggttgagagcgcgcgtcaggtgttcccactgacggggcgttatgcgcgccagtttgcc
tcgcaccgtctggcgctggtgggcgacgccgcacataccattcacccgctggcggggcag
ggggtaaatctcggctttatggatgctgcagagctgattgccgaactgaaacggttgcat
cgtcaggggaaagacatcgggcagtacatttatctgcgtcgctatgagcgtagccgcaag
cacagtgcggcgttgatgctggctggtatgcagggattccgcgatctgttttccggtacc
aatccggcgaaaaaactgctgcgtgatattggtttgaaactggccgacacgcttcctggc
gttaagccgcaacttatccgccaggcaatgggattaaacgatttgcctgaatggctgcgt
taa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 400 |
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| Protein Molecular Weight: | 44244 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 4K22 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >2-octaprenylphenol hydroxylase
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVQEPLAANAPPQLRVSAINAASEKL
LTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNK
AHQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLVIGADGANSWLRNKADIPLTF
WDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFASHRLALVGDAAHTIHPLAGQ
GVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGT
NPAKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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