FhuE receptor (P16869)

Identification
Name:FhuE receptor
Synonyms:
  • Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid
Gene Name:fhuE
Enzyme Class:Not Available
Biological Properties
General Function:Involved in receptor activity
Specific Function:Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid
Cellular Location:Cell outer membrane
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Transports:
Transport References:
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
Metabolites:
ECMDB IDNameView
ECMDB20516Ferric coprogenMetaboCard
ECMDB21225Hydrogen ionMetaboCard
GO Classification:
Component
cell part
membrane
Function
binding
cation binding
cation transmembrane transporter activity
di-, tri-valent inorganic cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
ion binding
ion transmembrane transporter activity
iron ion binding
iron ion transmembrane transporter activity
metal ion binding
molecular transducer activity
receptor activity
siderophore-iron transmembrane transporter activity
signal transducer activity
substrate-specific transmembrane transporter activity
transition metal ion binding
transmembrane transporter activity
transporter activity
Process
establishment of localization
siderophore transport
transport
Gene Properties
Blattner:b1102
Gene OrientationCounterclockwise
Centisome Percentage:24.97
Left Sequence End1158585
Right Sequence End1160774
Gene Sequence:
>2190 bp
ATGCTTTCAACACAATTTAACAGGGATAATCAATATCAAGCCATCACCAAACCGTCACTA
CTTGCCGGTTGCATAGCACTGGCACTATTACCTTCTGCCGCTTTTGCTGCACCAGCCACT
GAAGAAACGGTGATTGTTGAGGGTTCAGCCACAGCTCCAGATGATGGCGAAAATGATTAC
AGCGTAACGTCTACCTCTGCGGGTACCAAAATGCAGATGACTCAACGTGATATTCCTCAG
TCGGTCACTATTGTTAGCCAGCAGCGGATGGAAGATCAGCAGTTACAAACGCTGGGCGAA
GTGATGGAAAACACGCTGGGGATCAGCAAAAGTCAGGCGGATTCCGATCGTGCTCTTTAT
TATTCCCGCGGATTCCAGATCGATAACTATATGGTTGATGGTATCCCCACCTATTTTGAA
TCGCGCTGGAATCTGGGCGACGCACTTTCTGATATGGCACTCTTTGAACGCGTAGAAGTA
GTGCGTGGCGCGACAGGACTCATGACCGGGACGGGTAATCCATCTGCGGCAATTAATATG
GTTCGAAAACACGCGACCAGTCGTGAATTTAAAGGCGATGTCTCGGCGGAATACGGTAGC
TGGAACAAAGAACGGTATGTGGCGGATTTACAAAGCCCACTCACCGAAGACGGTAAAATC
CGCGCGCGAATTGTCGGCGGCTACCAGAATAACGACTCATGGCTGGACCGCTACAACAGT
GAAAAGACCTTCTTCTCGGGCATTGTCGATGCTGATTTAGGCGATCTTACGACGCTTTCA
GCCGGTTACGAATATCAGCGCATTGATGTTAATAGCCCTACCTGGGGCGGTTTACCGCGC
TGGAATACTGATGGCAGCAGCAACAGTTACGATCGCGCACGCAGTACCGCACCTGACTGG
GCGTACAACGATAAAGAGATCAACAAGGTCTTTATGACCCTGAAGCAGCAGTTTGCTGAT
ACCTGGCAAGCGACACTGAATGCCACCCACTCTGAAGTCGAATTTGACAGCAAAATGATG
TATGTCGATGCCTATGTAAACAAAGCGGATGGTATGCTGGTTGGGCCATACAGTAATTAT
GGACCTGGCTTTGATTATGTCGGCGGCACCGGTTGGAACAGTGGCAAACGTAAAGTTGAT
GCGCTGGATTTGTTCGCTGACGGTAGTTATGAATTGTTTGGTCGTCAGCACAATCTAATG
TTTGGTGGCAGTTACAGCAAACAAAACAATCGTTACTTCAGTTCATGGGCCAACATCTTC
CCGGATGAAATTGGCAGTTTCTACAACTTTAATGGCAATTTCCCACAAACCGACTGGTCA
CCACAGAGCCTGGCGCAGGACGATACCACACATATGAAATCGTTATATGCTGCCACTCGT
GTCACCCTTGCCGATCCGCTGCATCTGATCCTCGGCGCACGTTATACCAACTGGCGGGTT
GATACGCTGACTTACAGCATGGAGAAAAACCACACCACGCCTTACGCTGGTCTGGTGTTT
GACATCAATGACAACTGGTCGACCTACGCCAGCTATACCTCTATTTTCCAGCCGCAAAAT
GATCGTGACAGTTCAGGCAAATATCTGGCTCCAATCACCGGTAACAACTACGAGCTGGGT
CTGAAATCGGACTGGATGAATAGCCGTCTGACCACCACGTTAGCCATCTTCCGTATTGAG
CAGGATAATGTCGCTCAGTCCACCGGTACACCTATCCCCGGCAGCAACGGCGAAACCGCC
TATAAAGCGGTGGATGGGACAGTCAGTAAAGGGGTGGAATTTGAACTCAACGGCGCAATT
ACCGACAACTGGCAGCTGACATTTGGCGCAACGCGCTATATTGCAGAGGATAACGAAGGA
AACGCCGTTAATCCTAATCTGCCACGCACCACGGTTAAAATGTTCACCAGCTATCGGTTG
CCTGTCATGCCAGAGTTGACGGTCGGCGGTGGTGTTAACTGGCAAAATCGCGTGTATACC
GACACCGTGACGCCGTATGGCACCTTCCGCGCCGAGCAAGGTAGCTACGCGCTGGTGGAT
CTCTTCACCCGCTACCAGGTGACGAAAAACTTCTCGTTACAGGGGAACGTCAATAACCTG
TTCGACAAAACCTACGATACCAACGTGGAAGGTTCTATCGTCTACGGCACACCGCGTAAT
TTCAGCATTACCGGCACGTATCAATTCTGA
Protein Properties
Pfam Domain Function:
Protein Residues:729
Protein Molecular Weight:81232
Protein Theoretical pI:5
Signaling Regions:
  • 1-36
Transmembrane Regions:
  • None
Protein Sequence:
>FhuE receptor
MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETVIVEGSATAPDDGENDY
SVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALY
YSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEVVRGATGLMTGTGNPSAAINM
VRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
EKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDW
AYNDKEINKVFMTLKQQFADTWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNY
GPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLMFGGSYSKQNNRYFSSWANIF
PDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLAPITGNNYELG
LKSDWMNSRLTTTLAIFRIEQDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAI
TDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYT
DTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGTPRN
FSITGTYQF
References
External Links:
ResourceLink
Uniprot ID:P16869
Uniprot Name:FHUE_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:1651542
Ecogene ID:EG10306
Ecocyc:EG10306
ColiBase:b1102
Kegg Gene:b1102
EchoBASE ID:EB0302
CCDB:FHUE_ECOLI
BacMap:16129065
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • Sauer, M., Hantke, K., Braun, V. (1987). "Ferric-coprogen receptor FhuE of Escherichia coli: processing and sequence common to all TonB-dependent outer membrane receptor proteins." J Bacteriol 169:2044-2049. Pubmed: 3032906
  • Sauer, M., Hantke, K., Braun, V. (1990). "Sequence of the fhuE outer-membrane receptor gene of Escherichia coli K12 and properties of mutants." Mol Microbiol 4:427-437. Pubmed: 2162465