3-octaprenyl-4-hydroxybenzoate carboxy-lyase (P0AG03)

Identification
Name:3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Synonyms:
  • Polyprenyl p-hydroxybenzoate decarboxylase
Gene Name:ubiX
Enzyme Class:
Biological Properties
General Function:Coenzyme transport and metabolism
Specific Function:Specific function unknown
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
  • Metabolic pathways eco01100
  • Ubiquinone and other terpenoid-quinone biosynthesis ec00130
KEGG Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.03-Octaprenyl-4-hydroxybenzoate + 1.0Hydrogen ion → 1.02-Octaprenylphenol + 1.0Carbon dioxide
ReactionCard
1.02-Polyprenylphenol+1.0Thumb+1.0Thumb ↔ 1.04-Hydroxy-3-polyprenylbenzoate+1.0Thumb
1.02-Polyprenylphenol + 1.0Carbon dioxide + 1.04-Hydroxy-3-polyprenylbenzoate ↔ 1.04-Hydroxy-3-polyprenylbenzoate + 1.02-Polyprenylphenol
ReactionCard
1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.03-Octaprenyl-4-hydroxybenzoate ↔ 1.02-Octaprenylphenol + 1.0Carbon dioxide
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.03-Octaprenyl-4-hydroxybenzoate + 1.0Hydrogen ion → 1.02-Octaprenylphenol + 1.0Carbon dioxide
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB041202-OctaprenylphenolMetaboCard
ECMDB238132-PolyprenylphenolMetaboCard
ECMDB211693-Octaprenyl-4-hydroxybenzoateMetaboCard
ECMDB237564-Hydroxy-3-polyprenylbenzoateMetaboCard
ECMDB04030Carbon dioxideMetaboCard
ECMDB21225Hydrogen ionMetaboCard
GO Classification:
Function
carbon-carbon lyase activity
carboxy-lyase activity
catalytic activity
lyase activity
Gene Properties
Blattner:b2311
Gene OrientationCounterclockwise
Centisome Percentage:52.29
Left Sequence End2426079
Right Sequence End2426648
Gene Sequence:
>570 bp
ATGAAAAGAGTTTTGTTCTTTTTGCTGATGATATTTGTTAGTTTTGGTGTTATAGCTGAT
TGCGAAATACAAGCTAAAGATCATGATTGTTTTACTATTTTCGCTAAGGGTACTATTTTT
TCCGCGTTTCCTGTCTTAAATAATAAAGCCATGTGGAGATGGTATCAGAATGAGGACATC
GGTGAGTATTATTGGCAAACAGAACTGGGTACATGTAAAAATAATAAATTCACACCAAGC
GGGGCGAGACTCTTAATTCGCGTCGGGTCACTACGCCTTAATGAAAATCATGCCATCAAA
GGAACGTTGCAGGAGTTGATAAATACAGCAGAAAAAACGGCGTTTCTCGGCGATCGGTTT
AGAAGTTATATAAGAGCGGGTATCTATCAAAAAAAGAGCAGTGATCCAGTTCAGTTGTTG
GCAGTCCTTGATAATTCAATCATGGTAAAATATTTTAAAGATGAGAAACCAACTTATGCT
CGAATGACAGCACATCTCCCGAACAAAAATGAGTCTTACGAATGTTTAATAAAGATACAG
CATGAACTAATTCGTAGTGAAGAGAAATAA
Protein Properties
Pfam Domain Function:
Protein Residues:189
Protein Molecular Weight:20695
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALAD
VTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVL
CVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLDDVINQTVNRVLDQFAITLPE
DLFARWQGA
References
External Links:
ResourceLink
Uniprot ID:P0AG03
Uniprot Name:UBIX_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:4062296
Ecogene ID:EG11044
Ecocyc:EG11044
ColiBase:b2311
Kegg Gene:b2311
EchoBASE ID:EB1037
CCDB:UBIX_ECOLI
BacMap:16130246
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Nonet, M. L., Marvel, C. C., Tolan, D. R. (1987). "The hisT-purF region of the Escherichia coli K-12 chromosome. Identification of additional genes of the hisT and purF operons." J Biol Chem 262:12209-12217. Pubmed: 3040734
  • Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Horiuchi, T., et, a. l. .. (1997). "Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." DNA Res 4:91-113. Pubmed: 9205837