5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB (P0ADP0)

Identification
Name:5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB
Synonyms:Not Available
Gene Name:yigB
Enzyme Class:
Biological Properties
General Function:riboflavin biosynthetic process
Specific Function:Catalyzes the dephosphorylation of 5-amino-6-(5-phospho-D-ribitylamino)uracil, and thus could be involved in the riboflavin biosynthesis pathway (PubMed:24123841). Is also able to dephosphorylate flavin mononucleotide (FMN) and other phosphoric acid esters (PubMed:16990279) (PubMed:24123841). YigB is important for the formation of dormant persister cells (PubMed:18519731).
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:Not Available
SMPDB Reactions:
1.05-Amino-6-(5'-phosphoribitylamino)uracil+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.05-Amino-6-(5'-phosphoribitylamino)uracil + 1.0Water + 1.05-Amino-6-(5'-phosphoribitylamino)uracil → 1.0Phosphate + 1.05-Amino-6-ribitylamino uracil
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB211775-Amino-6-(5'-phosphoribitylamino)uracilMetaboCard
ECMDB041455-Amino-6-ribitylamino uracilMetaboCard
ECMDB01429PhosphateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
dephosphorylation
dormancy process
magnesium ion binding
phosphatase activity
riboflavin biosynthetic process
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>717
atgcgtttttaccggcctttggggcgcatctcggcgctcacctttgacctggatgatacc
ctttacgataaccgtccggtgattttgcgcaccgagcgagaggcgcttacctttgtgcaa
aattatcatccggcgctgcgcagcttccagaatgaagatctgcaacgcctgcgccaggcg
gtacgggaagcggaacccgagatttatcacgacgtgacgcgctggcgttttcgttcgatt
gaacaagcgatgctcgacgccgggctgagtgccgaagaagccagtgcaggcgcacacgca
gcaatgatcaactttgccaaatggcgcagccgaatcgacgtcccgcagcaaactcacgac
accttaaaacagctggcgaagaaatggccgctggtggcgatcaccaacggtaacgcccag
ccggagctgtttggtttgggggattattttgagtttgtgctgcgcgctggcccgcacggg
cgctcaaaaccgttcagcgatatgtactttttggctgcggaaaaactcaacgtgccgatc
ggcgagatcttacatgttggggacgatctcaccactgacgtgggtggggcaattcgcagc
ggaatgcaggcttgttggatcagaccggaaaatggcgatctgatgcaaacctgggacagc
cgtttactgccgcatctggaaatttcccggttggcatctctgacctcgctgatataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:238
Protein Molecular Weight:27121
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB
MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHPALRSFQNEDLQRLRQA
VREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAMINFAKWRSRIDVPQQTHD
TLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHGRSKPFSDMYFLAAEKLNVPI
GEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTWDSRLLPHLEISRLASLTSLI
References
External Links:
ResourceLink
Uniprot ID:P0ADP0
Uniprot Name:YIGB_ECOLI
CCDB:YIGB_ECOLI
General Reference:Not Available