Protein ddg (P0ACV2)

Identification
Name:Protein ddg
Synonyms:Not Available
Gene Name:ddg
Enzyme Class:
Biological Properties
General Function:Involved in transferase activity, transferring acyl groups
Specific Function:Specific function unknown
Cellular Location:Cell inner membrane; Single-pass membrane protein (Potential)
SMPDB Pathways:
  • lipopolysaccharide biosynthesis III PW002059
KEGG Pathways:Not Available
KEGG Reactions:
1.0Hexadecenoyl-[acyl-carrier protein]+1.0Thumb ↔ 1.0Thumb+1.0Acyl-carrier protein
1.0Hexadecenoyl-[acyl-carrier protein] + 1.0KDO(2)-lipid IV(A) ↔ 1.0(9Z)-Hexadec-9-enoyl-KDO2-lipid IV(A) + 1.0Acyl-carrier protein
ReactionCard
SMPDB Reactions:
1.0Thumb+1.0a palmitoleoyl-[acp]  → 1.0Thumb+1.0a holo-[acyl-carrier protein]
1.0a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVA + 1.0a palmitoleoyl-[acp]  → 1.0KDO2-(palmitoleoyl)-lipid IVA + 1.0a holo-[acyl-carrier protein]
ReactionCard
Complex Reactions:
1.0cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1)+1.0Thumb → 1.0acyl carrier protein+1.0KDO(2)-lipid IV(A) with palmitoleoyl
1.0cis-hexadec-9-enoyl-[acyl-carrier protein] (n-C16:1) + 1.0KDO(2)-lipid IV(A) → 1.0acyl carrier protein + 1.0KDO(2)-lipid IV(A) with palmitoleoyl
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB24178a-Kdo-(2->4)-a-Kdo-(2->6)-lipid IVAMetaboCard
ECMDB21235KDO(2)-lipid IV(A)MetaboCard
ECMDB20572KDO2-(palmitoleoyl)-lipid IVAMetaboCard
GO Classification:
Component
cell part
cell wall
external encapsulating structure
Gram-negative-bacterium-type cell wall
integral to membrane
intrinsic to membrane
membrane part
peptidoglycan-based cell wall
Function
acyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
Process
carbohydrate metabolic process
lipopolysaccharide core region biosynthetic process
metabolic process
oligosaccharide biosynthetic process
oligosaccharide metabolic process
primary metabolic process
Gene Properties
Blattner:b2378
Gene OrientationClockwise
Centisome Percentage:53.75
Left Sequence End2493667
Right Sequence End2494587
Gene Sequence:
>921 bp
ATGACTGATAAAATCGCGGTCCTGTTGGGTGGGACCTCCGCTGAGCGGGAAGTTTCTCTG
AATTCTGGCGCAGCGGTGTTAGCCGGACTGCGTGAAGGCGGTATTGACGCGTATCCTGTC
GACCCGAAAGAAGTCGACGTGACGCAACTGAAGTCGATGGGCTTTCAGAAAGTGTTTATC
GCGCTACACGGTCGCGGCGGTGAAGATGGTACGCTGCAGGGGATGCTCGAGCTGATGGGC
TTGCCTTATACCGGAAGCGGAGTGATGGCATCTGCGCTTTCAATGGATAAACTACGCAGC
AAACTTCTATGGCAAGGTGCCGGTTTACCGGTCGCGCCGTGGGTAGCGTTAACCCGCGCA
GAGTTTGAAAAAGGCCTGAGCGATAAGCAGTTAGCAGAAATTTCTGCTCTGGGTTTGCCG
GTTATCGTTAAGCCGAGCCGCGAAGGTTCCAGTGTGGGAATGTCAAAAGTAGTAGCAGAA
AATGCTCTACAAGATGCATTAAGATTGGCATTTCAGCACGATGAAGAAGTATTGATTGAA
AAATGGCTAAGTGGGCCGGAGTTCACGGTTGCGATACTCGGTGAAGAAATTTTACCGTCA
ATACGTATTCAACCGTCCGGAACCTTCTATGATTATGAGGCGAAGTATCTCTCTGATGAG
ACACAGTATTTCTGCCCCGCAGGTCTGGAAGCGTCACAAGAGGCCAATTTGCAGGCATTA
GTGCTGAAAGCATGGACGACGTTAGGTTGCAAAGGATGGGGACGTATTGACGTTATGCTG
GACAGCGATGGACAGTTTTATCTGCTGGAAGCCAATACCTCACCGGGTATGACCAGCCAC
AGCCTGGTGCCGATGGCGGCACGTCAGGCAGGTATGAGCTTCTCGCAGTTGGTAGTACGA
ATTCTGGAACTGGCGGACTAA
Protein Properties
Pfam Domain Function:
Protein Residues:306
Protein Molecular Weight:35493
Protein Theoretical pI:10
Signaling Regions:
  • None
Transmembrane Regions:
  • 20-40
Protein Sequence:
>Protein ddg
MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRIGAMARPFLKRRESIAR
KNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDSRVRKWFDVEGLDNLKRAQ
MQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQLMEWVQTRGRMRSNKAMIGRN
NLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVT
MVRKADYSGYRLFITPEMEGYPTDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVG
ESSLYI
References
External Links:
ResourceLink
Uniprot ID:P0ACV2
Uniprot Name:DDG_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:21321973
Ecogene ID:EG12901
Ecocyc:EG12901
ColiBase:b2378
Kegg Gene:b2378
EchoBASE ID:EB2738
CCDB:DDG_ECOLI
BacMap:90111426
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Horiuchi, T., et, a. l. .. (1997). "Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." DNA Res 4:91-113. Pubmed: 9205837