Aliphatic sulfonates import ATP-binding protein SsuB (P0AAI1)

Identification
Name:Aliphatic sulfonates import ATP-binding protein SsuB
Synonyms:Not Available
Gene Name:ssuB
Enzyme Class:Not Available
Biological Properties
General Function:Involved in nucleotide binding
Specific Function:Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable)
Cellular Location:Cell inner membrane; Peripheral membrane protein
SMPDB Pathways:
KEGG Pathways:
SMPDB Reactions:
1.0Alkyl Sulfate+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Alkyl Sulfate+1.0Thumb
1.0Alkyl Sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Alkyl Sulfate + 1.0ADP
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1.0Thumb+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Butanesulfonate + 1.0ADP
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1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.03-(N-morpholino)propanesulfonate → 1.0Phosphate + 1.0Hydrogen ion + 1.0Adenosine diphosphate + 1.03-(N-morpholino)propanesulfonate + 1.0ADP
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1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0 ethanesulfonate → 1.0Hydrogen ion + 1.0Phosphate + 1.0Adenosine diphosphate + 1.0 ethanesulfonate + 1.0ADP
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1.0Thumb+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0 isethionate → 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0Phosphate + 1.0 isethionate + 1.0ADP
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1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0methanesulfonate + 1.0Methanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0methanesulfonate + 1.0ADP
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1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb
1.0Cysteine-S-sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Cysteine-S-sulfate + 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0ADP
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Isethionic acid → 1.0ADP + 1.0Hydrogen ion + 1.0Isethionic acid + 1.0Phosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0ADP + 1.0Butanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Ethanesulfonate → 1.0ADP + 1.0Ethanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Methanesulfonate → 1.0ADP + 1.0Hydrogen ion + 1.0Methanesulfonate + 1.0Phosphate
ReactionCard
1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Water + 1.0Sulfoacetate → 1.0ADP + 1.0Hydrogen ion + 1.0Phosphate + 1.0Sulfoacetate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB24254 ethanesulfonateMetaboCard
ECMDB24255 isethionateMetaboCard
ECMDB242533-(N-morpholino)propanesulfonateMetaboCard
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB21313ButanesulfonateMetaboCard
ECMDB00731Cysteine-S-sulfateMetaboCard
ECMDB21330EthanesulfonateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB21233Isethionic acidMetaboCard
ECMDB21344MethanesulfonateMetaboCard
ECMDB01429PhosphateMetaboCard
ECMDB21358SulfoacetateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Component
cell part
membrane
plasma membrane
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
ATPase activity
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
nucleoside binding
nucleoside-triphosphatase activity
nucleotide binding
purine nucleoside binding
pyrophosphatase activity
transporter activity
Process
establishment of localization
transport
Gene Properties
Blattner:b0933
Gene OrientationCounterclockwise
Centisome Percentage:21.39
Left Sequence End992500
Right Sequence End993267
Gene Sequence:
>768 bp
ATGAATACTGCTCGTCTGAACCAGGGCACGCCATTGTTGCTCAATGCAGTAAGCAAACAT
TACGCGGAAAATATCGTCCTGAACCAACTGGATTTACATATTCCGGCAGGTCAGTTTGTG
GCGGTGGTGGGCCGCAGCGGTGGTGGCAAAAGTACCCTGCTGCGCCTGCTGGCAGGTCTG
GAAACGCCAACCGCAGGCGATGTGTTAGCGGGCACCACACCGCTGGCTGAAATTCAGGAA
GACACGCGAATGATGTTTCAGGATGCGCGTCTGCTACCGTGGAAATCGGTGATTGATAAC
GTTGGGTTAGGCCTTAAAGGCCAGTGGCGCGATGCCGCACGTCGAGCGTTGGCTGCGGTA
GGACTGGAGAATCGCGCAGGGGAATGGCCTGCCGCACTTTCTGGCGGGCAGAAACAGCGA
GTGGCGCTGGCAAGAGCGTTGATTCATCGACCGGGATTATTGTTGCTTGATGAACCGCTC
GGGGCGCTGGACGCCTTAACGCGACTCGAGATGCAGGATTTGATTGTGTCACTTTGGCAG
GAGCACGGCTTTACCGTACTGTTGGTGACGCATGATGTGAGCGAAGCGGTAGCGATGGCT
GACCGGGTGCTGTTAATTGAAGAGGGAAAAATTGGTCTGGATTTGACAGTGGATATCCCC
CGTCCGCGTCGATTAGGGTCGGTGCGATTAGCGGAGCTGGAAGCGGAGGTGTTGCAACGG
GTGATGCAACGTGGTGAATCTGAAACTCGCCTGAGAAAACAGGGGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:255
Protein Molecular Weight:27738
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Aliphatic sulfonates import ATP-binding protein SsuB
MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGL
ETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAV
GLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQ
EHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDIPRPRRLGSVRLAELEAEVLQR
VMQRGESETRLRKQG
References
External Links:
ResourceLink
Uniprot ID:P0AAI1
Uniprot Name:SSUB_ECOLI
GenBank Gene ID:AJ237695
Genebank Protein ID:4583570
Ecogene ID:EG12358
Ecocyc:EG12358
ColiBase:b0933
Kegg Gene:b0933
EchoBASE ID:EB2261
CCDB:SSUB_ECOLI
BacMap:16128900
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Borodovsky, M., Rudd, K. E., Koonin, E. V. (1994). "Intrinsic and extrinsic approaches for detecting genes in a bacterial genome." Nucleic Acids Res 22:4756-4767. Pubmed: 7984428
  • Eichhorn, E., van der Ploeg, J. R., Leisinger, T. (2000). "Deletion analysis of the Escherichia coli taurine and alkanesulfonate transport systems." J Bacteriol 182:2687-2695. Pubmed: 10781534
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • McCaman, M. T., Gabe, J. D. (1986). "The nucleotide sequence of the pepN gene and its over-expression in Escherichia coli." Gene 48:145-153. Pubmed: 3549459
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • van der Ploeg, J. R., Eichhorn, E., Leisinger, T. (2001). "Sulfonate-sulfur metabolism and its regulation in Escherichia coli." Arch Microbiol 176:1-8. Pubmed: 11479697
  • van Der Ploeg, J. R., Iwanicka-Nowicka, R., Bykowski, T., Hryniewicz, M. M., Leisinger, T. (1999). "The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl." J Biol Chem 274:29358-29365. Pubmed: 10506196