Aliphatic sulfonates import ATP-binding protein SsuB (P0AAI1)

Identification
Name:Aliphatic sulfonates import ATP-binding protein SsuB
Synonyms:Not Available
Gene Name:ssuB
Enzyme Class:Not Available
Biological Properties
General Function:Involved in nucleotide binding
Specific Function:Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable)
Cellular Location:Cell inner membrane; Peripheral membrane protein
SMPDB Pathways:
KEGG Pathways:
Transports:
    Transport References:Not Available
    SMPDB Reactions:
    1.0Alkyl Sulfate+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Alkyl Sulfate+1.0Thumb
    1.0Alkyl Sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Alkyl Sulfate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0Butanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.03-(N-morpholino)propanesulfonate → 1.0Phosphate + 1.0Hydrogen ion + 1.0Adenosine diphosphate + 1.03-(N-morpholino)propanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0 ethanesulfonate → 1.0Hydrogen ion + 1.0Phosphate + 1.0Adenosine diphosphate + 1.0 ethanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0 isethionate → 1.0Adenosine diphosphate + 1.0Hydrogen ion + 1.0Phosphate + 1.0 isethionate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb → 1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0methanesulfonate+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0methanesulfonate + 1.0Methanesulfonate → 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0methanesulfonate + 1.0ADP
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Adenosine diphosphate+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Cysteine-S-sulfate + 1.0Adenosine triphosphate + 1.0Water → 1.0Cysteine-S-sulfate + 1.0Adenosine diphosphate + 1.0Phosphate + 1.0Hydrogen ion + 1.0ADP
    ReactionCard
    Complex Reactions:
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Isethionic acid → 1.0ADP + 1.0Hydrogen ion + 1.0Isethionic acid + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Butanesulfonate → 1.0ADP + 1.0Butanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Ethanesulfonate → 1.0ADP + 1.0Ethanesulfonate + 1.0Hydrogen ion + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Methanesulfonate → 1.0ADP + 1.0Hydrogen ion + 1.0Methanesulfonate + 1.0Phosphate
    ReactionCard
    1.0Thumb+1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb+1.0Thumb
    1.0Adenosine triphosphate + 1.0Water + 1.0Sulfoacetate → 1.0ADP + 1.0Hydrogen ion + 1.0Phosphate + 1.0Sulfoacetate
    ReactionCard
    Metabolites:
    ECMDB IDNameView
    ECMDB24254 ethanesulfonateMetaboCard
    ECMDB24255 isethionateMetaboCard
    ECMDB242533-(N-morpholino)propanesulfonateMetaboCard
    ECMDB00538Adenosine triphosphateMetaboCard
    ECMDB01341ADPMetaboCard
    ECMDB21313ButanesulfonateMetaboCard
    ECMDB00731Cysteine-S-sulfateMetaboCard
    ECMDB21330EthanesulfonateMetaboCard
    ECMDB21225Hydrogen ionMetaboCard
    ECMDB21233Isethionic acidMetaboCard
    ECMDB21344MethanesulfonateMetaboCard
    ECMDB01429PhosphateMetaboCard
    ECMDB21358SulfoacetateMetaboCard
    ECMDB00494WaterMetaboCard
    GO Classification:
    Component
    cell part
    membrane
    plasma membrane
    Function
    adenyl nucleotide binding
    adenyl ribonucleotide binding
    ATP binding
    ATPase activity
    binding
    catalytic activity
    hydrolase activity
    hydrolase activity, acting on acid anhydrides
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    nucleoside binding
    nucleoside-triphosphatase activity
    nucleotide binding
    purine nucleoside binding
    pyrophosphatase activity
    transporter activity
    Process
    establishment of localization
    transport
    Gene Properties
    Blattner:b0933
    Gene OrientationCounterclockwise
    Centisome Percentage:21.39
    Left Sequence End992500
    Right Sequence End993267
    Gene Sequence:
    >768 bp
ATGAATACTGCTCGTCTGAACCAGGGCACGCCATTGTTGCTCAATGCAGTAAGCAAACAT
TACGCGGAAAATATCGTCCTGAACCAACTGGATTTACATATTCCGGCAGGTCAGTTTGTG
GCGGTGGTGGGCCGCAGCGGTGGTGGCAAAAGTACCCTGCTGCGCCTGCTGGCAGGTCTG
GAAACGCCAACCGCAGGCGATGTGTTAGCGGGCACCACACCGCTGGCTGAAATTCAGGAA
GACACGCGAATGATGTTTCAGGATGCGCGTCTGCTACCGTGGAAATCGGTGATTGATAAC
GTTGGGTTAGGCCTTAAAGGCCAGTGGCGCGATGCCGCACGTCGAGCGTTGGCTGCGGTA
GGACTGGAGAATCGCGCAGGGGAATGGCCTGCCGCACTTTCTGGCGGGCAGAAACAGCGA
GTGGCGCTGGCAAGAGCGTTGATTCATCGACCGGGATTATTGTTGCTTGATGAACCGCTC
GGGGCGCTGGACGCCTTAACGCGACTCGAGATGCAGGATTTGATTGTGTCACTTTGGCAG
GAGCACGGCTTTACCGTACTGTTGGTGACGCATGATGTGAGCGAAGCGGTAGCGATGGCT
GACCGGGTGCTGTTAATTGAAGAGGGAAAAATTGGTCTGGATTTGACAGTGGATATCCCC
CGTCCGCGTCGATTAGGGTCGGTGCGATTAGCGGAGCTGGAAGCGGAGGTGTTGCAACGG
GTGATGCAACGTGGTGAATCTGAAACTCGCCTGAGAAAACAGGGGTAA
    Protein Properties
    Pfam Domain Function:
    Protein Residues:255
    Protein Molecular Weight:27738
    Protein Theoretical pI:7
    Signaling Regions:
    • None
    Transmembrane Regions:
    • None
    Protein Sequence:
    >Aliphatic sulfonates import ATP-binding protein SsuB
MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGL
ETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAV
GLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRLEMQDLIVSLWQ
EHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDIPRPRRLGSVRLAELEAEVLQR
VMQRGESETRLRKQG
    References
    External Links:
    ResourceLink
    Uniprot ID:P0AAI1
    Uniprot Name:SSUB_ECOLI
    GenBank Gene ID:AJ237695
    Genebank Protein ID:4583570
    Ecogene ID:EG12358
    Ecocyc:EG12358
    ColiBase:b0933
    Kegg Gene:b0933
    EchoBASE ID:EB2261
    CCDB:SSUB_ECOLI
    BacMap:16128900
    General Reference:
    • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
    • Borodovsky, M., Rudd, K. E., Koonin, E. V. (1994). "Intrinsic and extrinsic approaches for detecting genes in a bacterial genome." Nucleic Acids Res 22:4756-4767. Pubmed: 7984428
    • Eichhorn, E., van der Ploeg, J. R., Leisinger, T. (2000). "Deletion analysis of the Escherichia coli taurine and alkanesulfonate transport systems." J Bacteriol 182:2687-2695. Pubmed: 10781534
    • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
    • McCaman, M. T., Gabe, J. D. (1986). "The nucleotide sequence of the pepN gene and its over-expression in Escherichia coli." Gene 48:145-153. Pubmed: 3549459
    • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
    • van der Ploeg, J. R., Eichhorn, E., Leisinger, T. (2001). "Sulfonate-sulfur metabolism and its regulation in Escherichia coli." Arch Microbiol 176:1-8. Pubmed: 11479697
    • van Der Ploeg, J. R., Iwanicka-Nowicka, R., Bykowski, T., Hryniewicz, M. M., Leisinger, T. (1999). "The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl." J Biol Chem 274:29358-29365. Pubmed: 10506196