ECMDB

Identification

Name:

Alpha-D-glucose 1-phosphate phosphatase YihX

Synonyms:

Not Available

Gene Name:

yihX

Enzyme Class:

3.1.3.10

Biological Properties

General Function:

dephosphorylation

Specific Function:

Catalyzes the dephosphorylation of alpha-D-glucose 1-phosphate (Glc1P) and, to a lesser extent, of other sugar phosphates (PubMed:16990279) (PubMed:25484615). Has no activity with the beta form of Glc1P. In addition, YihX has significant phosphatase activity against pyridoxal phosphate (PLP) and low beta-phosphoglucomutase activity (PubMed:16990279).

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Glycolysis / Gluconeogenesis ec00010
Microbial metabolism in diverse environments ec01120

KEGG Reactions:

1.0

↔

1.0

1.0Glucose 1-phosphate + 1.0Water ↔ 1.0D-Glucose + 1.0Phosphate
ReactionCard

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
dephosphorylation
glucose-1-phosphatase activity
magnesium ion binding
manganese ion binding

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>600
atgctctatatctttgatttaggtaatgtgattgtcgatatcgactttaaccgtgtgctg
ggagcctggagcgatttaacgcgtattccgctggcatcgcttaagaagagttttcatatg
ggggaggcgtttcatcagcatgagcgtggggaaattagcgacgaagcgttcgcagaggcg
ctgtgtcatgagatggctctaccgctaagctacgagcagttctctcacggctggcaggcg
gtgtttgttgcgctgcgcccggaagtgatcgccatcatgcataaactgcgtgagcagggg
catcgcgtggtggtgctttccaataccaaccgcctgcataccaccttctggccggaagaa
tacccggaaattcgtgatgctgctgaccatatctatctgtcgcaagatctggggatgcgc
aaacctgaagcacgaatttaccagcatgttttgcaggcggaaggtttttcacccagcgat
acggtctttttcgacgataacgccgataatatagaaggagccaatcagctgggcattacc
agtattctggtgaaagataaaaccaccatcccggactatttcgcgaaggtgttatgctaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

199

Protein Molecular Weight:

22731

Protein Theoretical pI:

Not Available

PDB File:

2B0C

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Alpha-D-glucose 1-phosphate phosphatase YihX
MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLASLKKSFHMGEAFHQHERGEISDEAFAEA
LCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHRVVVLSNTNRLHTTFWPEE
YPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSDTVFFDDNADNIEGANQLGIT
SILVKDKTTIPDYFAKVLC

References

External Links:

Resource	Link
Uniprot ID:	P0A8Y3
Uniprot Name:	YIHX_ECOLI
PDB ID:	2B0C
CCDB:	YIHX_ECOLI

General Reference:

Not Available

Alpha-D-glucose 1-phosphate phosphatase YihX (P0A8Y3)