2-dehydro-3-deoxy-6-phosphogalactonate aldolase (Q6BF16)

Identification
Name:2-dehydro-3-deoxy-6-phosphogalactonate aldolase
Synonyms:
  • 2-oxo-3-deoxygalactonate 6-phosphate aldolase
  • 6-phospho-2-dehydro-3-deoxygalactonate aldolase
Gene Name:dgoA
Enzyme Class:
Biological Properties
General Function:Involved in catalytic activity
Specific Function:2-dehydro-3-deoxy-D-galactonate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.02-Dehydro-3-deoxy-D-galactonate-6-phosphate ↔ 1.0D-Glyceraldehyde 3-phosphate + 1.0Pyruvic acid
ReactionCard
SMPDB Reactions:
1.02-dehydro-3-deoxy-D-galactonate 6-phosphate+1.0Thumb → 1.0Thumb+1.0D-Glyceraldehyde 3-phosphate+1.0Thumb
1.02-dehydro-3-deoxy-D-galactonate 6-phosphate + 1.02-Dehydro-3-deoxy-D-galactonate 6-phosphate → 1.0Pyruvic acid + 1.0D-Glyceraldehyde 3-phosphate + 1.0D-Glyceraldehyde 3-phosphate
ReactionCard
EcoCyc Reactions:
1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.02-Dehydro-3-deoxy-D-galactonate-6-phosphate ↔ 1.0D-Glyceraldehyde 3-phosphate + 1.0Pyruvic acid
ReactionCard
Complex Reactions:
1.0Thumb → 1.0Thumb+1.0Thumb
1.02-Dehydro-3-deoxy-D-galactonate 6-phosphate → 1.0Pyruvic acid + 1.0D-Glyceraldehyde 3-phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB230812-Dehydro-3-deoxy-D-galactonate 6-phosphateMetaboCard
ECMDB040452-Dehydro-3-deoxy-D-galactonate-6-phosphateMetaboCard
ECMDB01112D-Glyceraldehyde 3-phosphateMetaboCard
ECMDB00243Pyruvic acidMetaboCard
GO Classification:
Function
catalytic activity
Process
metabolic process
Gene Properties
Blattner:b4477
Gene OrientationCounterclockwise
Centisome Percentage:83.43
Left Sequence End3871018
Right Sequence End3871635
Gene Sequence:
>618 bp
ATGACAACCCAGTATGGATTTTTTATTGATTCCAGCCGTTGCACCGGTTGCAAAACCTGC
GAGCTGGCCTGTAAAGACTACAAAGATTTGACGCCAGAAGTCAGCTTCCGCCGCATTTAT
GAATATGCTGGCGGCGACTGGCAGGAAGATAACGGTGTCTGGCACCAGAACGTGTTTGCC
TACTATCTGTCGATTTCATGTAACCACTGCGAAGATCCGGCTTGTACTAAAGTCTGCCCG
AGCGGTGCGATGCATAAACGTGAAGATGGTTTTGTTGTGGTCGATGAAGATGTGTGCATT
GGCTGCCGCTACTGCCATATGGCTTGCCCGTATGGCGCACCGCAATATAACGAAACGAAA
GGCCATATGACCAAATGCGATGGTTGTTATGACCGTGTTGCGGAGGGTAAAAAGCCGATC
TGTGTTGAATCTTGTCCGCTGCGGGCGCTGGATTTCGGCCCTATCGACGAGCTGCGTAAA
AAACATGGCGATCTGGCGGCCGTTGCGCCGTTGCCGCGAGCTCACTTTACCAAACCGAAT
ATTGTGATCAAACCCAATGCCAATAGCCGCCCGACCGGGGATACCACTGGCTATCTGGCA
AACCCGAAGGAGGTGTGA
Protein Properties
Pfam Domain Function:
Protein Residues:205
Protein Molecular Weight:21390
Protein Theoretical pI:5
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>2-dehydro-3-deoxy-6-phosphogalactonate aldolase
MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKA
LIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEA
GAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPENLAQWIDAGCAGAGLGSDLY
RAGQSVERTAQQAAAFVKAYREAVQ
References
External Links:
ResourceLink
Uniprot ID:Q6BF16
Uniprot Name:DGOA_ECOLI
GenBank Gene ID:U00096
Genebank Protein ID:1787122
Ecogene ID:EG11716
Ecocyc:EG11716
ColiBase:b4477
Kegg Gene:b4477
EchoBASE ID:EB1667
CCDB:DGOA_ECOLI
BacMap:49176391
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Burland, V., Plunkett, G. 3rd, Daniels, D. L., Blattner, F. R. (1993). "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Genomics 16:551-561. Pubmed: 7686882
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Riley, M., Abe, T., Arnaud, M. B., Berlyn, M. K., Blattner, F. R., Chaudhuri, R. R., Glasner, J. D., Horiuchi, T., Keseler, I. M., Kosuge, T., Mori, H., Perna, N. T., Plunkett, G. 3rd, Rudd, K. E., Serres, M. H., Thomas, G. H., Thomson, N. R., Wishart, D., Wanner, B. L. (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34:1-9. Pubmed: 16397293