Fructose-6-phosphate aldolase 1 (P78055)

Identification
Name:Fructose-6-phosphate aldolase 1
Synonyms:Not Available
Gene Name:fsaA
Enzyme Class:Not Available
Biological Properties
General Function:Involved in catalytic activity
Specific Function:D-fructose 6-phosphate = glycerone + D- glyceraldehyde 3-phosphate
Cellular Location:Cytoplasm
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
EcoCyc Reactions:
1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0Fructose 6-phosphate ↔ 1.0Dihydroxyacetone + 1.0D-Glyceraldehyde 3-phosphate
ReactionCard
Complex Reactions:
1.0Thumb → 1.0Thumb+1.0Thumb
1.0Fructose 6-phosphate → 1.0Dihydroxyacetone + 1.0D-Glyceraldehyde 3-phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB01112D-Glyceraldehyde 3-phosphateMetaboCard
ECMDB01882DihydroxyacetoneMetaboCard
ECMDB00124Fructose 6-phosphateMetaboCard
GO Classification:
Function
catalytic activity
Process
carbohydrate metabolic process
metabolic process
primary metabolic process
Gene Properties
Blattner:b0825
Gene OrientationClockwise
Centisome Percentage:18.60
Left Sequence End862865
Right Sequence End863527
Gene Sequence:
>663 bp
ATGGAACTGTATCTGGATACTTCAGACGTTGTTGCGGTGAAGGCGCTGTCACGTATTTTT
CCGCTGGCGGGTGTGACCACTAACCCAAGCATTATCGCCGCGGGTAAAAAACCGCTGGAT
GTTGTGCTTCCGCAACTTCATGAAGCGATGGGCGGTCAGGGGCGTCTGTTTGCCCAGGTA
ATGGCTACCACTGCCGAAGGGATGGTTAATGACGCGCTTAAGCTGCGTTCTATTATTGCG
GATATCGTGGTGAAAGTTCCGGTGACCGCCGAGGGGCTGGCAGCTATTAAGATGTTAAAA
GCGGAAGGGATTCCGACGCTGGGAACCGCGGTATATGGCGCAGCACAAGGGCTGCTGTCG
GCGCTGGCAGGTGCGGAATATGTTGCGCCTTACGTTAATCGTATTGATGCTCAGGGCGGT
AGCGGCATTCAGACTGTGACCGACTTACACCAGTTATTGAAAATGCATGCGCCGCAGGCG
AAAGTGCTGGCAGCGAGTTTCAAAACCCCGCGTCAGGCGCTGGACTGCTTACTGGCAGGA
TGTGAATCAATTACTCTGCCACTGGATGTGGCACAACAGATGATTAGCTATCCGGCGGTT
GATGCCGCTGTGGCGAAGTTTGAGCAGGACTGGCAGGGAGCGTTTGGCAGAACGTCGATT
TAA
Protein Properties
Pfam Domain Function:
Protein Residues:220
Protein Molecular Weight:22997
Protein Theoretical pI:6
PDB File:1L6W
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Fructose-6-phosphate aldolase 1
MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLPQLHEAMGGQGRLFAQV
MATTAEGMVNDALKLRSIIADIVVKVPVTAEGLAAIKMLKAEGIPTLGTAVYGAAQGLLS
ALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQAKVLAASFKTPRQALDCLLAG
CESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRTSI
References
External Links:
ResourceLink
Uniprot ID:P78055
Uniprot Name:FSAA_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674771
PDB ID:1L6W
Ecogene ID:EG13471
Ecocyc:EG13471
ColiBase:b0825
Kegg Gene:b0825
EchoBASE ID:EB3244
CCDB:FSAA_ECOLI
BacMap:90111174
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232
  • Schurmann, M., Sprenger, G. A. (2001). "Fructose-6-phosphate aldolase is a novel class I aldolase from Escherichia coli and is related to a novel group of bacterial transaldolases." J Biol Chem 276:11055-11061. Pubmed: 11120740