| Identification |
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| Name: | Glutathione S-transferase YfcF |
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| Synonyms: | Not Available |
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| Gene Name: | yfcF |
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| Enzyme Class: | |
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| Biological Properties |
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| General Function: | response to hydrogen peroxide |
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| Specific Function: | Exhibits glutathione (GSH) S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB); however this activity is as low as 1% of that of GstA. Also displays a GSH-dependent peroxidase activity toward cumene hydroperoxide. Is involved in defense against oxidative stress, probably via its peroxidase activity. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | |
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| KEGG Pathways: | - Drug metabolism - cytochrome P450 ec00982
- Glutathione metabolism ec00480
- Metabolism of xenobiotics by cytochrome P450 ec00980
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| KEGG Reactions: | |
1.0RX | + | 1.0 | ↔ | 1.0 | + | 1.0R-S-Glutathione |
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| Metabolites: | |
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| GO Classification: | | Function |
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| glutathione transferase activity | | peroxidase activity | | response to hydrogen peroxide |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >645
atgagtaaacccgctatcacgctttggtcagatgcccactttttctccccttatgtgtta
tccgcctgggtggcgttgcaggaaaaaggcctgtcgtttcatatcaagaccatcgacctc
gacagcggtgaacatttgcagccgacgtggcaaggttacggtcagacacgccgtgtgccg
ttattacaaatcgatgattttgagttgagtgaatcttctgccattgcggagtatctggaa
gatcgatttgcgccaccgacctgggaacgtatttatccgcttgatttagaaaatcgtgcg
cgtgcacgacagattcaggcctggctgcgcagcgatctgatgcccatccgcgaagagcgt
ccgacggatgttgtctttgcgggggcgaaaaaagcgccactaacggccgagggaaaagcc
agtgcagagaaactgttcgcgatggcagaacatttgttagtactgggtcagccgaattta
tttggtgaatggtgcattgctgatactgatctggcgctaatgattaaccgcctggtacta
catggcgatgaggtgccagaacgcctggtggattatgcaacattccagtggcagcgagcg
tctgtccagcgttttattgcactttcggcgaagcaatctggctga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 214 |
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| Protein Molecular Weight: | 24325 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 3BBY |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Glutathione S-transferase YfcF
MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVP
LLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREER
PTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLVLGQPNLFGEWCIADTDLALMINRLVL
HGDEVPERLVDYATFQWQRASVQRFIALSAKQSG |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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