Putative undecaprenyl-diphosphatase ybjG (P75806)

Identification
Name:Putative undecaprenyl-diphosphatase ybjG
Synonyms:
  • Undecaprenyl pyrophosphate phosphatase
Gene Name:ybjG
Enzyme Class:
Biological Properties
General Function:Involved in catalytic activity
Specific Function:Overexpression leads to increased undecaprenyl diphosphatase activity and to increased resistance to bacitracin. May have a preferred substrate other than undecaprenyl diphosphate in vivo
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0di-trans,poly-cis-Undecaprenyl diphosphate+1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0di-trans,poly-cis-Undecaprenyl diphosphate + 1.0Water + 1.0Undecaprenyl diphosphate ↔ 1.0Di-trans,poly-cis-undecaprenyl phosphate + 1.0Phosphate
ReactionCard
EcoCyc Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Undecaprenyl diphosphate + 1.0Water → 1.0Hydrogen ion + 1.0Di-trans,poly-cis-undecaprenyl phosphate + 1.0Phosphate
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb+1.0Thumb
1.0Water + 1.0Undecaprenyl diphosphate → 1.0Hydrogen ion + 1.0Phosphate + 1.0Undecaprenyl phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB20310Di-trans,poly-cis-undecaprenyl phosphateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB21380Inorganic phosphateMetaboCard
ECMDB01429PhosphateMetaboCard
ECMDB01469Undecaprenyl diphosphateMetaboCard
ECMDB20208Undecaprenyl phosphateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Component
cell part
membrane
Function
catalytic activity
Gene Properties
Blattner:b0841
Gene OrientationCounterclockwise
Centisome Percentage:19.01
Left Sequence End882015
Right Sequence End882611
Gene Sequence:
>597 bp
ATGATCGAATTTGTTTATCCGCACACGCAGCTGGTTGCGGGTGTGGATGAAGTCGGACGC
GGGCCGTTAGTTGGCGCGGTCGTCACCGCTGCGGTGATCCTTGACCCGGCGCGCCCGATT
GCCGGGCTGAATGATTCCAAAAAGCTGAGCGAAAAACGCCGTCTGGCGCTCTATGAAGAG
ATCAAAGAGAAAGCGTTGAGCTGGAGTCTGGGCCGCGCGGAACCCCACGAAATCGACGAG
CTGAACATTCTTCATGCGACCATGCTGGCGATGCAGCGTGCCGTCGCTGGGCTGCATATT
GCGCCGGAATATGTGTTGATTGATGGTAACCGCTGCCCGAAATTACCGATGCCTGCGATG
GCTGTGGTGAAAGGCGATAGCCGCGTACCGGAAATCAGTGCCGCGTCTATCCTGGCGAAA
GTGACGCGTGACGCCGAAATGGCGGCGCTGGATATTGTTTTCCCGCAATATGGTTTTGCC
CAACACAAAGGGTACCCAACCGCTTTTCATCTGGAAAAACTGGCTGAACACGGCGCGACC
GAACACCATCGGCGCAGCTTTGGGCCTGTCAAACGCGCACTGGGACTTGCGTCCTGA
Protein Properties
Pfam Domain Function:
Protein Residues:198
Protein Molecular Weight:22398
Protein Theoretical pI:9
Signaling Regions:
  • None
Transmembrane Regions:
  • 28-48
  • 58-78
  • 121-143
  • 150-172
Protein Sequence:
>Putative undecaprenyl-diphosphatase ybjG
MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAVVLWLWGLTAQRQLVIKI
AIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFPSDHGTVIFTFALAFLCWH
RLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIGCLSAQIIWQAMGHKLYQRLQ
SWYRVCFALPIRKGWVRD
References
External Links:
ResourceLink
Uniprot ID:P75806
Uniprot Name:YBJG_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674372
Ecogene ID:EG13676
Ecocyc:EG13676
ColiBase:b0841
Kegg Gene:b0841
EchoBASE ID:EB3440
CCDB:YBJG_ECOLI
BacMap:16128809
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Daley, D. O., Rapp, M., Granseth, E., Melen, K., Drew, D., von Heijne, G. (2005). "Global topology analysis of the Escherichia coli inner membrane proteome." Science 308:1321-1323. Pubmed: 15919996
  • El Ghachi, M., Derbise, A., Bouhss, A., Mengin-Lecreulx, D. (2005). "Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli." J Biol Chem 280:18689-18695. Pubmed: 15778224
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Oshima, T., Aiba, H., Baba, T., Fujita, K., Hayashi, K., Honjo, A., Ikemoto, K., Inada, T., Itoh, T., Kajihara, M., Kanai, K., Kashimoto, K., Kimura, S., Kitagawa, M., Makino, K., Masuda, S., Miki, T., Mizobuchi, K., Mori, H., Motomura, K., Nakamura, Y., Nashimoto, H., Nishio, Y., Saito, N., Horiuchi, T., et, a. l. .. (1996). "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." DNA Res 3:137-155. Pubmed: 8905232