| Identification |
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| Name: | Aldehyde reductase YahK |
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| Synonyms: | Not Available |
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| Gene Name: | yahK |
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| Enzyme Class: | |
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| Biological Properties |
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| General Function: | zinc ion binding |
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| Specific Function: | Catalyzes the reduction of a wide range of aldehydes into their corresponding alcohols. Has a strong preference for NADPH over NADH as the electron donor. Cannot use a ketone as substrate. Is a major source of NADPH-dependent aldehyde reductase activity in E.coli. The in vivo functions of YahK has yet to be determined. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | - Caprolactam degradation ec00930
- Glycerolipid metabolism ec00561
- Glycolysis / Gluconeogenesis ec00010
- Metabolic pathways eco01100
- Microbial metabolism in diverse environments ec01120
- Pentose and glucuronate interconversions ec00040
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| KEGG Reactions: | |
1.0Alcohol | + | 1.0 | ↔ | 1.0 | + | 1.0 | + | 1.0 |
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| Metabolites: | |
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| GO Classification: | | Function |
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| alcohol dehydrogenase (NADP+) activity | | zinc ion binding |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1050
atgaagatcaaagctgttggtgcatattccgctaaacaaccacttgaaccgatggatatc
acccggcgtgaaccgggaccgaatgatgtcaaaatcgaaatcgcttactgtggcgtttgc
cattccgatctccaccaggtccgttccgagtgggcggggacggtttacccctgcgtgccg
ggtcatgaaattgtggggcgtgtggtagccgttggtgatcaggtagaaaaatatgcgccg
ggcgatctggtcggtgtcggctgcattgtcgacagttgtaaacattgcgaagagtgtgaa
gacgggttggaaaactactgtgatcacatgaccggcacctataactcgccgacgccggac
gaaccgggccatactctgggcggctactcacaacagatcgtcgttcatgagcgatatgtt
ctgcgtattcgtcacccgcaagagcagctggcggcggtggctcctttgttgtgtgcaggg
atcaccacgtattcgccgctacgtcactggcaggccgggccgggtaaaaaagtgggcgtg
gtcggcatcggcggtctgggacatatggggattaagctggcccacgcgatgggggcacat
gtggtggcatttaccacttctgaggcaaaacgcgaagcggcaaaagccctgggggccgat
gaagttgttaactcacgcaatgccgatgagatggcggctcatctgaagagtttcgatttc
attttgaatacagtagctgcgccacataatctcgacgattttaccaccttgctgaagcgt
gatggcaccatgacgctggttggtgcgcctgcgacaccgcataaatcgccggaagttttc
aacctgatcatgaaacgccgtgcgatagccggttctatgattggcggcattccagaaact
caggagatgctcgatttttgcgccgaacatggcatcgtggctgatatagagatgattcgg
gccgatcaaattaatgaagcctatgagcgaatgctgcgcggtgatgtgaaatatcgtttt
gttatcgataatcgcacactaacagactga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 349 |
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| Protein Molecular Weight: | 37978 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1UUF |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Aldehyde reductase YahK
MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP
GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD
EPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGV
VGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDF
ILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPET
QEMLDFCAEHGIVADIEMIRADQINEAYERMLRGDVKYRFVIDNRTLTD |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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