Putative phosphotransferase enzyme IIB component sgcB (P58035)

Identification
Name:Putative phosphotransferase enzyme IIB component sgcB
Synonyms:
  • Putative PTS system EIIB component
Gene Name:sgcB
Enzyme Class:
Biological Properties
General Function:Involved in sugar:hydrogen symporter activity
Specific Function:The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
Cellular Location:Cytoplasm (Probable)
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Protein N(pi)-phospho-L-histidine ↔ 1.0Thumb+1.0Protein histidine
1.0Galactitol + 1.0Protein N(pi)-phospho-L-histidine ↔ 1.0Galactitol 1-phosphate + 1.0Protein histidine
ReactionCard
1.0Protein N(pi)-phospho-L-histidine+1.0Sugar ↔ 1.0Protein histidine+1.0Thumb
1.0Protein N(pi)-phospho-L-histidine + 1.0Sugar ↔ 1.0Protein histidine + 1.0Sugar phosphate
ReactionCard
Complex Reactions:
1.0Protein EIIB N(pi)-phospho-L-histidine/cysteine+1.0Thumb → 1.0protein EIIB+1.0sugar phosphate
1.0Protein EIIB N(pi)-phospho-L-histidine/cysteine + 1.0Sucrose → 1.0protein EIIB + 1.0sugar phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00107GalactitolMetaboCard
ECMDB20149Galactitol 1-phosphateMetaboCard
ECMDB00258SucroseMetaboCard
GO Classification:
Function
carbohydrate transmembrane transporter activity
cation transmembrane transporter activity
cation:sugar symporter activity
ion transmembrane transporter activity
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
solute:cation symporter activity
substrate-specific transmembrane transporter activity
sugar:hydrogen symporter activity
transmembrane transporter activity
transporter activity
Process
carbohydrate transport
establishment of localization
phosphoenolpyruvate-dependent sugar phosphotransferase system
transport
Gene Properties
Blattner:b4565
Gene OrientationCounterclockwise
Centisome Percentage:97.60
Left Sequence End4528278
Right Sequence End4528556
Gene Sequence:
>279 bp
ATGAATCGGCCAGCAATATTAAAAAAGAAAGCAGCCAAAGATGTTGCTTCAGTATTAAAA
ATAATATTTTTATTTTATTTGTTCCTCATAGCTAGATTAAAACAACGTTATTCGATACGT
GAAATTAAGAGGGATTTATGGAACATCAGAGAAAACTATTCCAGCAACGCGGCTATAGCG
AAGATCTATTGCCGAAAACGCAAAGCCAGCGGACCTGGAAAACATTTAACTATTTTACCT
TATGGATGGGTTCGGTTCATAACGTTCCCAATTATGTGA
Protein Properties
Pfam Domain Function:
Protein Residues:92
Protein Molecular Weight:9803
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Putative phosphotransferase enzyme IIB component sgcB
MKKILVACGTGMSTSTMIAHKLQEFLTEQGISATTAQCCLNEIPLNCNGMDLIVTSMRTN
SDYGIPTLNGAALLTGINDDALKQQIKALLTQ
References
External Links:
ResourceLink
Uniprot ID:P58035
Uniprot Name:SGCB_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674648
Ecogene ID:EG14343
Ecocyc:EG14343
ColiBase:b4565
Kegg Gene:b4565
EchoBASE ID:EB4089
CCDB:SGCB_ECOLI
BacMap:94541133
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553