Identification
Name:Protein frlC
Synonyms:Not Available
Gene Name:frlC
Enzyme Class:Not Available
Biological Properties
General Function:Carbohydrate transport and metabolism
Specific Function:Not clear, may be involved in an isomerization step
Cellular Location:Not Available
SMPDB Pathways:
  • Fructoselysine and Psicoselysine Degradation PW002049
KEGG Pathways:Not Available
Transports:
Transport References:
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
SMPDB Reactions:
1.0Thumb1.01-[(5-Amino-5-carboxypentyl)amino]-1-deoxyfructose
1.0Fructoselysine ↔ 1.01-[(5-Amino-5-carboxypentyl)amino]-1-deoxyfructose
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB20557FructoselysineMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b4474
Gene OrientationClockwise
Centisome Percentage:75.44
Left Sequence End3500362
Right Sequence End3501192
Gene Sequence:
>831 bp
ATGTCGCAGGCTGCTCTGAACACGCGAAACAGCGAAGAAGAGGTTTCTTCTCGCCGCAAT
AATGGAACGCGTCTGGCGGGGATCCTTTTCCTGCTGACCGTTTTAACGACAGTGTTGGTG
AGCGGCTGGGTCGTGTTGGGCTGGATGGAAGATGCGCAACGCCTGCCGCTCTCAAAGCTG
GTGTTGACCGGTGAACGCCATTACACACGTAATGACGATATCCGGCAGTCGATCCTGGCA
TTGGGTGAGCCGGGTACCTTTATGACCCAGGATGTCAACATCATCCAGACGCAAATAGAA
CAACGCCTGCCGTGGATTAAGCAGGTGAGCGTCAGAAAGCAGTGGCCTGATGAATTGAAG
ATTCATCTGGTTGAATATGTGCCGATTGCGCGGTGGAATGATCAACATATGGTAGACGCG
GAAGGAAATACCTTCAGCGTGCCGCCAGAACGCACCAGCAAGCAGGTGCTTCCAATGCTG
TATGGCCCGGAAGGCAGCGCCAATGAAGTGTTGCAGGGCTATCGCGAAATGGGGCAGATG
CTGGCAAAGGACAGATTTACTCTGAAGGAAGCGGCGATGACCGCGCGGCGTTCCTGGCAG
TTGACGCTGAATAACGATATTAAGCTCAATCTTGGCCGGGGCGATACGATGAAACGTTTG
GCTCGCTTTGTAGAACTTTATCCGGTTTTACAGCAGCAGGCGCAAACCGATGGCAAACGG
ATTAGCTACGTTGATTTGCGTTATGACTCTGGAGCGGCAGTAGGCTGGGCGCCCTTGCCG
CCAGAGGAATCTACTCAGCAACAAAATCAGGCACAGGCAGAACAACAATGA
Protein Properties
Pfam Domain Function:
Protein Residues:276
Protein Molecular Weight:31169
Protein Theoretical pI:5
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Protein frlC
MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDLKAGGIKQIKALAQTYQ
MPIIGYTPETNGYPYNMMLGDEHMRRESLDMIKLAMDMAKEMNAGYTLISAAHAGYLTPP
NVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCNANDVLHALALVPSPRLFSMV
DICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTHYIPGEGKMPLRELMRDIIERGY
EGYCTVELVTMYMNEPRLYARQALERFRALLPEDER
References
External Links:
ResourceLink
Uniprot ID:P45541
Uniprot Name:FRLC_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:21321974
Ecogene ID:EG12910
Ecocyc:EG12910
ColiBase:b4474
Kegg Gene:b4474
EchoBASE ID:EB2747
CCDB:FRLC_ECOLI
BacMap:49176341
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Riley, M., Abe, T., Arnaud, M. B., Berlyn, M. K., Blattner, F. R., Chaudhuri, R. R., Glasner, J. D., Horiuchi, T., Keseler, I. M., Kosuge, T., Mori, H., Perna, N. T., Plunkett, G. 3rd, Rudd, K. E., Serres, M. H., Thomas, G. H., Thomson, N. R., Wishart, D., Wanner, B. L. (2006). "Escherichia coli K-12: a cooperatively developed annotation snapshot--2005." Nucleic Acids Res 34:1-9. Pubmed: 16397293
  • Wiame, E., Delpierre, G., Collard, F., Van Schaftingen, E. (2002). "Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli." J Biol Chem 277:42523-42529. Pubmed: 12147680