Uncharacterized Nudix hydrolase nudL (P43337)

Identification
Name:Uncharacterized Nudix hydrolase nudL
Synonyms:Not Available
Gene Name:nudL
Enzyme Class:Not Available
Biological Properties
General Function:Involved in hydrolase activity
Specific Function:Probably mediates the hydrolysis of some nucleoside diphosphate derivatives
Cellular Location:Cytoplasmic
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
EcoCyc Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0Phosphohydroxypyruvic acid + 1.0Water → 1.0Hydroxypyruvic acid + 1.0Phosphate
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB01352Hydroxypyruvic acidMetaboCard
ECMDB01429PhosphateMetaboCard
ECMDB01024Phosphohydroxypyruvic acidMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
binding
catalytic activity
cation binding
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
ion binding
magnesium ion binding
manganese ion binding
metal ion binding
transition metal ion binding
Process
cellular nitrogen compound metabolic process
metabolic process
nitrogen compound metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleoside diphosphate metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
Gene Properties
Blattner:b1813
Gene OrientationClockwise
Centisome Percentage:40.83
Left Sequence End1894194
Right Sequence End1894772
Gene Sequence:
>579 bp
ATGTACCAGGATCTTATTCGTAACGAACTGAACGAAGCGGCGGAAACGCTGGCTAACTTT
TTAAAAGATGACGCCAATATTCACGCCATTCAGCGCGCGGCGGTCCTGTTAGCAGACAGC
TTTAAAGCCGGTGGCAAAGTGCTTTCCTGCGGCAACGGCGGTTCCCATTGCGACGCTATG
CACTTTGCCGAAGAGTTGACCGGTCGCTACCGTGAAAACCGTCCGGGCTACCCGGCGATT
GCTATTTCTGACGTTAGTCATATTTCCTGCGTCGGTAATGATTTCGGTTTCAATGATATT
TTCTCCCGCTACGTTGAAGCGGTAGGTCGCGAAGGCGATGTACTGCTGGGGATCTCCACC
TCCGGTAACTCTGCAAACGTGATCAAAGCGATCGCAGCGGCGCGTGAGAAGGGAATGAAA
GTGATCACCCTGACCGGTAAAGACGGCGGCAAAATGGCTGGCACGGCGGATATCGAAATT
CGCGTACCGCACTTTGGTTATGCCGACCGCATTCAGGAGATTCACATTAAAGTGATCCAT
ATCCTGATCCAGTTGATTGAAAAAGAGATGGTTAAGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:192
Protein Molecular Weight:21435
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Uncharacterized Nudix hydrolase nudL
MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAG
QVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIP
PDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGI
IRELALQIGVKP
References
External Links:
ResourceLink
Uniprot ID:P43337
Uniprot Name:NUDL_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:4902958
Ecogene ID:EG12693
Ecocyc:EG12693
ColiBase:b1813
Kegg Gene:b1813
EchoBASE ID:EB2556
CCDB:NUDL_ECOLI
BacMap:16129767
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Borodovsky, M., McIninch, J. D., Koonin, E. V., Rudd, K. E., Medigue, C., Danchin, A. (1995). "Detection of new genes in a bacterial genome using Markov models for three gene classes." Nucleic Acids Res 23:3554-3562. Pubmed: 7567469
  • Goncharoff, P., Nichols, B. P. (1984). "Nucleotide sequence of Escherichia coli pabB indicates a common evolutionary origin of p-aminobenzoate synthetase and anthranilate synthetase." J Bacteriol 159:57-62. Pubmed: 6330050
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Itoh, T., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Kasai, H., Kimura, S., Kitakawa, M., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomura, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Seki, Y., Horiuchi, T., et, a. l. .. (1996). "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map." DNA Res 3:379-392. Pubmed: 9097040
  • Su, H. S., Lang, B. F., Newman, E. B. (1989). "L-serine degradation in Escherichia coli K-12: cloning and sequencing of the sdaA gene." J Bacteriol 171:5095-5102. Pubmed: 2504697