Putative galactosamine-6-phosphate isomerase (P42912)

Identification
Name:Putative galactosamine-6-phosphate isomerase
Synonyms:
  • Galactosamine-6-phosphate deaminase
Gene Name:agaI
Enzyme Class:Not Available
Biological Properties
General Function:Involved in carbohydrate metabolic process
Specific Function:D-galactosamine 6-phosphate + H(2)O = D- tagatose 6-phosphate + NH(3)
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
KEGG Reactions:
1.0Thumb+1.0Thumb ↔ 1.0Thumb+1.0Thumb
1.0D-Galactosamine 6-phosphate + 1.0Water ↔ 1.0D-Tagatose 6-phosphate + 1.0Ammonia
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb → 1.0Thumb+1.0Thumb
1.0D-Galactosamine 6-phosphate + 1.0Water → 1.0D-Tagatose 6-phosphate + 1.0Ammonia
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00051AmmoniaMetaboCard
ECMDB20141D-Galactosamine 6-phosphateMetaboCard
ECMDB06873D-Tagatose 6-phosphateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Function
catalytic activity
glucosamine-6-phosphate deaminase activity
intramolecular oxidoreductase activity
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
isomerase activity
Process
alcohol metabolic process
amino sugar metabolic process
carbohydrate metabolic process
glucosamine metabolic process
metabolic process
monosaccharide metabolic process
N-acetylglucosamine metabolic process
primary metabolic process
small molecule metabolic process
Gene Properties
Blattner:b3141
Gene OrientationClockwise
Centisome Percentage:70.79
Left Sequence End3284292
Right Sequence End3285047
Gene Sequence:
>756 bp
ATGGAACGAGGCACTGCGTCTGGTGGTGCCTCTTTACTTAAGGAATTTCATCCTGTGCAA
ACCCTTCAGCAAGTTGAAAACTATACGGCCTTAAGTGAACGTGCCAGCGAATATTTATTG
GCCGTGATCCGTAGCAAACCGAATGCCGTGATTTGCCTGGCGACCGGAGCCACGCCATTA
CTGACGTATCATTATCTGGTAGAAAAAATCCACCAGCAGCAGGTTGATGTCAGCCAGCTC
ACCTTCGTGAAGCTCGACGAATGGGTGGATCTGCCATTAACGATGCCAGGCACCTGCGAA
ACTTTCCTGCAACAGCATATCGTGCAGCCGCTGGGGCTACGTGAAGACCAGCTCATCAGC
TTTCGCTCCGAAGAGATAAATGAGACAGAGTGCGAACGGGTAACGAACCTGATTGCGCGC
AAAGGCGGTCTGGATTTATGCGTTCTCGGATTGGGGAAAAACGGTCATCTTGGGCTGAAC
GAACCGGGAGAAAGCCTGCAACCGGCCTGCCATATCAGTCAACTTGATGCCAGAACACAG
CAACATGAGATGTTAAAAACCGCGGGTCGCCCCGTGACTCGTGGGATCACCTTAGGCCTG
AAGGATATTCTCAATGCCCGCGAAGTTTTGTTACTGGTGACTGGCGAAGGAAAGCAGGAT
GCGACAGATCGTTTTCTCACGGCTAAAGTCTCTACCGCTATCCCGGCTTCATTTTTATGG
CTGCACAGTAACTTTATTTGTTTAATTAACACCTAA
Protein Properties
Pfam Domain Function:
Protein Residues:251
Protein Molecular Weight:27724
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Putative galactosamine-6-phosphate isomerase
MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIRSKPNAVICLATGATPL
LTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETFLQQHIVQPLGLREDQLIS
FRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLNEPGESLQPACHISQLDARTQ
QHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGKQDATDRFLTAKVSTAIPASFLW
LHSNFICLINT
References
External Links:
ResourceLink
Uniprot ID:P42912
Uniprot Name:AGAI_ECOLI
GenBank Gene ID:AF228498
Genebank Protein ID:8895757
Ecogene ID:EG12772
Ecocyc:EG12772
ColiBase:b3141
Kegg Gene:b3141
EchoBASE ID:EB2625
CCDB:AGAI_ECOLI
BacMap:16131033
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Brinkkotter, A., Kloss, H., Alpert, C., Lengeler, J. W. (2000). "Pathways for the utilization of N-acetyl-galactosamine and galactosamine in Escherichia coli." Mol Microbiol 37:125-135. Pubmed: 10931310
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Reizer, J., Ramseier, T. M., Reizer, A., Charbit, A., Saier, M. H. Jr (1996). "Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli." Microbiology 142 ( Pt 2):231-250. Pubmed: 8932697