2,3-diketo-L-gulonate TRAP transporter small permease protein yiaM (P37674)

Identification
Name:2,3-diketo-L-gulonate TRAP transporter small permease protein yiaM
Synonyms:Not Available
Gene Name:yiaM
Enzyme Class:Not Available
Biological Properties
General Function:Carbohydrate transport and metabolism
Specific Function:Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate
Cellular Location:Cell inner membrane; Multi-pass membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Transports:
Transport References:
  • Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831
  • Uniprot Consortium (2012). "Reorganizing the protein space at the Universal Protein Resource (UniProt)." Nucleic Acids Res 40:D71-D75. Pubmed: 22102590
Metabolites:
ECMDB IDNameView
ECMDB065112,3-Diketo-L-gulonateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB00751L-Threo-2-pentuloseMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b3577
Gene OrientationClockwise
Centisome Percentage:80.66
Left Sequence End3742351
Right Sequence End3742824
Gene Sequence:
>474 bp
ATGGGCAGGATAAGCTCGGGAGGAATGATGTTTAAGGCAATAACGACAGTCGCCGCTCTG
GTCATCGCCACCAGTGCAATGGCGCAGGATGATTTAACCATTAGCAGCCTTGCAAAGGGC
GAAACCACCAAAGCTGCATTTAATCAGATGGTACAAGGGCATAAGCTGCCTGCCTGGGTG
ATGAAAGGCGGTACTTATACTCCCGCACAAACCGTAACGTTGGGAGATGAGACGTATCAG
GTGATGAGCGCGTGCAAACCGCATGACTGTGGCTCGCAACGTATCGCTGTGATGTGGTCC
GAGAAATCTAATCAGATGACGGGGCTGTTCTCGACTATTGATGAGAAAACGTCGCAAGAG
AAACTCACCTGGCTGAATGTGAACGATGCGCTTTCGATTGATGGTAAAACGGTGTTGTTC
GCGGCGTTGACCGGCAGCCTGGAAAACCATCCGGATGGCTTTAATTTTAAATAA
Protein Properties
Pfam Domain Function:
Protein Residues:157
Protein Molecular Weight:17516
Protein Theoretical pI:8
Signaling Regions:
  • None
Transmembrane Regions:
  • 7-29
  • 44-66
  • 79-98
  • 113-135
Protein Sequence:
>2,3-diketo-L-gulonate TRAP transporter small permease protein yiaM
MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYLFVWLTFIGAIVAFMDN
AHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLKTIQDWSDYSPILGLPIGL
MYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA
References
External Links:
ResourceLink
Uniprot ID:P37674
Uniprot Name:YIAM_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:4902956
Ecogene ID:EG12281
Ecocyc:EG12281
ColiBase:b3577
Kegg Gene:b3577
EchoBASE ID:EB2189
CCDB:YIAM_ECOLI
BacMap:16131448
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Daley, D. O., Rapp, M., Granseth, E., Melen, K., Drew, D., von Heijne, G. (2005). "Global topology analysis of the Escherichia coli inner membrane proteome." Science 308:1321-1323. Pubmed: 15919996
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Plantinga, T. H., Van Der Does, C., Badia, J., Aguilar, J., Konings, W. N., Driessen, A. J. (2004). "Functional characterization of the Escherichia coli K-12 yiaMNO transport protein genes." Mol Membr Biol 21:51-57. Pubmed: 14668138
  • Plantinga, T. H., van der Does, C., Tomkiewicz, D., van Keulen, G., Konings, W. N., Driessen, A. J. (2005). "Deletion of the yiaMNO transporter genes affects the growth characteristics of Escherichia coli K-12." Microbiology 151:1683-1689. Pubmed: 15870475
  • Sofia, H. J., Burland, V., Daniels, D. L., Plunkett, G. 3rd, Blattner, F. R. (1994). "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes." Nucleic Acids Res 22:2576-2586. Pubmed: 8041620
  • Thomas, G. H., Southworth, T., Leon-Kempis, M. R., Leech, A., Kelly, D. J. (2006). "Novel ligands for the extracellular solute receptors of two bacterial TRAP transporters." Microbiology 152:187-198. Pubmed: 16385129