Identification
Name:Fe(3+) ions import ATP-binding protein FbpC
Synonyms:Not Available
Gene Name:fbpC
Enzyme Class:
Biological Properties
General Function:Involved in nucleotide binding
Specific Function:Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system
Cellular Location:Cell inner membrane; Peripheral membrane protein
SMPDB Pathways:Not Available
KEGG Pathways:
Complex Reactions:
1.0Thumb+1.0Thumb+1.0Fe(3+)(Out)1.0Thumb+1.0Thumb+1.0Fe(3+)(In)
1.0Adenosine triphosphate + 1.0Water + 1.0Fe(3+)(Out) → 1.0ADP + 1.0Inorganic phosphate + 1.0Fe(3+)(In)
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
ECMDB21380Inorganic phosphateMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:
Component
ATP-binding cassette (ABC) transporter complex
cell part
macromolecular complex
membrane
protein complex
Function
adenyl nucleotide binding
adenyl ribonucleotide binding
ATP binding
ATPase activity
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
nucleoside binding
nucleoside-triphosphatase activity
nucleotide binding
purine nucleoside binding
pyrophosphatase activity
transporter activity
Process
establishment of localization
transport
Gene Properties
Blattner:b0262
Gene OrientationCounterclockwise
Centisome Percentage:5.97
Left Sequence End276980
Right Sequence End278026
Gene Sequence:
>1047 bp
ATGACTCAGAAAAATTTCGTTGAACTGCGCAACGTCACTAAACGATTTGGCAGTAATACG
GTAATCGACAATATCAACCTCACCATCCCGCAGGGGCAAATGGTGACGCTGCTCGGCCCG
TCCGGCTGCGGCAAAACCACTATTTTGCGCCTGGTTGCCGGGCTGGAAAAACCGAGCGAA
GGGCAAATTTTCATTGATGGCGAAGACGTCACCCATCGCTCTATTCAGCAGCGCGATATC
TGTATGGTGTTTCAGTCCTATGCCCTGTTCCCGCATATGTCGCTGGGAGAGAATGTCGGT
TATGGCCTGAAAATGCTCGGCGTACCGCGCGCAGAGCTGAAAGCCCGCGTCAAAGAGGCG
TTGGCGATGGTGGATCTGGAAGGATTCGAAGACCGCTTTGTCGATCAGATCTCCGGCGGG
CAGCAGCAGCGCGTGGCGCTGGCCCGCGCGCTGATCCTCAAGCCGAAAGTGCTGCTGTTT
GATGAGCCGTTGAGTAACCTCGACGCCAACCTGCGTCGCAGCATGCGCGACAAGATCCGC
GAGTTGCAAAAGCAGTTTGATATCACCTCGCTGTACGTCACCCACGATCAGAGCGAAGCC
TTTGCGGTTTCTGATACTGTGCTGGTGATGAACAAGGGACACATCATGCAGATCGGCTCA
CCGCAGGATCTTTACCGCCAGCCCGCCTCCCGCTTTATGGCGAGCTTTATGGGCGATGCC
AACCTGTTCCCGGCAACCTTCAGCGACGGATACGTTGATATCTACGGCTATCATCTGCCG
CGCCCGCTGCACTTTGGTACACAGGGTGAAGGGATGGTCGGTGTGCGCCCGGAAGCGATC
ACGCTCAGCGATCGCGGCGAAGAGAGCCAGCGCTGCGTGATCCGCCATGTCGCCTATATG
GGGCCGCAGTATGAAGTGACGGTGGAATGGCACGGGCAGGAGATATTATTGCAGGTCAAC
GCTACGCGTCTGCAACCGGACGTCGGCGAGCAGTATTATCTTGAAATCCATCCGTACGGC
ATGTTTGTTCTGGCGGATGCGGCATAA
Protein Properties
Pfam Domain Function:
Protein Residues:348
Protein Molecular Weight:39059
Protein Theoretical pI:6
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Fe(3+) ions import ATP-binding protein FbpC
MTQKNFVELRNVTKRFGSNTVIDNINLTIPQGQMVTLLGPSGCGKTTILRLVAGLEKPSE
GQIFIDGEDVTHRSIQQRDICMVFQSYALFPHMSLGENVGYGLKMLGVPRAELKARVKEA
LAMVDLEGFEDRFVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMRDKIR
ELQKQFDITSLYVTHDQSEAFAVSDTVLVMNKGHIMQIGSPQDLYRQPASRFMASFMGDA
NLFPATFSDGYVDIYGYHLPRPLHFGTQGEGMVGVRPEAITLSDRGEESQRCVIRHVAYM
GPQYEVTVEWHGQEILLQVNATRLQPDVGEQYYLEIHPYGMFVLADAA
References
External Links:
ResourceLink
Uniprot ID:P37009
Uniprot Name:FBPC_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:85674406
Ecogene ID:EG12340
Ecocyc:EG12340
ColiBase:b0262
Kegg Gene:b0262
EchoBASE ID:EB2244
CCDB:FBPC_ECOLI
BacMap:90111106
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Volkert, M. R., Loewen, P. C., Switala, J., Crowley, D., Conley, M. (1994). "The delta (argF-lacZ)205(U169) deletion greatly enhances resistance to hydrogen peroxide in stationary-phase Escherichia coli." J Bacteriol 176:1297-1302. Pubmed: 8113168