| Identification |
|---|
| Name: | Inorganic triphosphatase |
|---|
| Synonyms: | Not Available |
|---|
| Gene Name: | ygiF |
|---|
| Enzyme Class: | |
|---|
| Biological Properties |
|---|
| General Function: | metabolic process |
|---|
| Specific Function: | Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), which could be cytotoxic because of its high affinity for calcium ion, thereby interfering with calcium signaling. It also hydrolyzes slowly thiamine triphosphatase (ThTP). YgiF is a specific PPPase, but it contributes only marginally to the total PPPase activity in E.coli, where the main enzyme responsible for hydrolysis of PPPi is inorganic pyrophosphatase (PPase). |
|---|
| Cellular Location: | Not Available |
|---|
| SMPDB Pathways: | Not Available |
|---|
| KEGG Pathways: | Not Available |
|---|
| KEGG Reactions: | |
|---|
| Metabolites: | |
|---|
| GO Classification: | | Function |
|---|
| metabolic process | | triphosphatase activity |
|
|---|
| Gene Properties |
|---|
| Blattner: | Not Available |
|---|
| Gene Orientation | Not Available |
|---|
| Centisome Percentage: | Not Available |
|---|
| Left Sequence End | Not Available |
|---|
| Right Sequence End | Not Available |
|---|
| Gene Sequence: | >1302
atggctcaggaaatcgaattaaagtttattgttaatcacagtgccgttgaggcgttgcgt
gaccatctcaatacgctgggcggcgagcaccatgaccccgtgcagttgctgaatatttac
tacgaaacgccggataactggctgcgtgggcacgatatgggcttacgtattcgtggcgaa
aacggtcgctatgagatgaccatgaaagttgcaggaagagtgacaggcggcttacatcag
cgcccggaatataacgtggcgttgagcgaaccgacgctcgacctggcgcagttaccgacg
gaagtctggccgaacggcgaattgcccgccgatctcgcctcccgcgtgcagccgctgttc
agcaccgatttttatcgcgaaaaatggctggtggcggtcgatggtagccaaattgaaatc
gccctcgaccagggggaagtgaaagcgggtgaatttgctgaacctatctgtgagctggaa
ctggaactgcttagcggcgacacgcgcgcggtgctgaaactggcgaaccaactggtatcg
caaaccggattacgccagggcagcctgagcaaagcggcgcgtggctatcatctggcgcag
ggcaatccggcgcgtgaaatcaaaccgaccaccattttgcatgttgcggcaaaagccgat
gtggaacaggggctggaagcggcgctcgagctggcgttagcgcaatggcagtatcatgaa
gaactgtgggtacgcggcaacgatgcggcgaaagaacaggtgctggcagccattagcctg
gtccgtcatacgctgatgctgttcggtggtattgtgccgcgtaaagcgagcactcactta
cgtgatctgctgactcaatgcgaggcgaccattgcttctgcggtgtctgccgtgacggcg
gtctactctaccgaaacggcaatggcgaagctggcgttgaccgaatggttggtaagcaaa
gcatggcagccatttttagatgccaaagcgcagggcaaaatcagcgactccttcaaacgc
tttgccgatatccatctttcccgccatgccgctgaactgaaaagcgttttctgccagccg
ttaggcgatcgctaccgtgaccagttgccacgcctgacgcgtgatattgactcaatactg
ttgctggcgggttactatgatcctgtcgtcgcgcaagcctggctggagaactggcagggg
ctgcatcacgctattgcgaccgggcaacgcatcgaaattgaacatttccgtaatgaggca
aacaatcaggaaccgttctggttgcacagcggaaaacgttaa |
|---|
| Protein Properties |
|---|
| Pfam Domain Function: | Not Available |
|---|
| Protein Residues: | 433 |
|---|
| Protein Molecular Weight: | 48388 |
|---|
| Protein Theoretical pI: | Not Available |
|---|
| Signaling Regions: | Not Available |
|---|
| Transmembrane Regions: | Not Available |
|---|
| Protein Sequence: | >Inorganic triphosphatase
MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGE
NGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLF
STDFYREKWLVAVDGSQIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVS
QTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAALELALAQWQYHE
ELWVRGNDAAKEQVLAAISLVRHTLMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTA
VYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQP
LGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLHHAIATGQRIEIEHFRNEA
NNQEPFWLHSGKR |
|---|
| References |
|---|
| External Links: | |
|---|
| General Reference: | Not Available |
|---|
