Protein hipA (P23874)

Identification
Name:Protein hipA
Synonyms:Not Available
Gene Name:hipA
Enzyme Class:
Biological Properties
General Function:Involved in ATP binding
Specific Function:Unbalanced or excessive expression of hipA is toxic to the cell
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
KEGG Reactions:
1.0Thumb+1.0Protein ↔ 1.0Thumb+1.0Thumb
1.0Adenosine triphosphate + 1.0Protein ↔ 1.0ADP + 1.0Phosphoprotein
ReactionCard
Complex Reactions:
1.0Thumb+1.0a protein → 1.0Thumb+1.0a phosphoprotein
1.0Adenosine triphosphate + 1.0a protein → 1.0ADP + 1.0a phosphoprotein
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB00538Adenosine triphosphateMetaboCard
ECMDB01341ADPMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1323 bp
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCC
AACGGCGCGCACACCTTTAAGTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACAG
TTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCTCTGATGCCGTATTTAACTTC
TTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCC
GTGACGTTAATACCCGAAGACGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTT
ACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAGCAGATATCCCGCTAGGCATG
ATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATT
AAATTACCGATTGGCGAAATCAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTT
GATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTTGGGTGAATGTTCCGGACGCA
GAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGT
TTACCTTCATCGGTGAAATATGAATCAGATGGAGGCCCACGCATCGCGCGGATCATGGCT
TTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATGATTTTATGAAATTCCAGGTC
TTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTT
GGCGGTACGGGAATACACATCAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAA
GGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATTTTTTGGCGACAGCAAAGGTG
CTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACG
GCAGTTGAAAGCAATGTGTTGAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAG
TGA
Protein Properties
Pfam Domain Function:
Protein Residues:440
Protein Molecular Weight:49275
Protein Theoretical pI:8
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Protein hipA
MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLSLPLQRGNITSDAVFNF
FDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVTLIPEDETVTHPIMAWEKL
TEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTALLRIGNDWCIPKGITPTTHII
KLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVPDAEIIKAGNVRALAVERFDRRW
NAERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIARIMAFLMGSSEALKDRYDFMKFQV
FQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDIISAFPVLGGTGIHISDLKLAMGLNASK
GKKTAIDKIYPRHFLATAKVLRFPEVQMHEILSDFARMIPAALDNVKTSLPTDFPENVVT
AVESNVLRLHGRLSREYGSK
References
External Links:
ResourceLink
Uniprot ID:P23874
Uniprot Name:HIPA_ECOLI
GenBank Gene ID:M61242
Genebank Protein ID:146354
CCDB:HIPA_ECOLI
General Reference:
  • Black, D. S., Irwin, B., Moyed, H. S. (1994). "Autoregulation of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis." J Bacteriol 176:4081-4091. Pubmed: 8021189
  • Black, D. S., Kelly, A. J., Mardis, M. J., Moyed, H. S. (1991). "Structure and organization of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesis." J Bacteriol 173:5732-5739. Pubmed: 1715862
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553