ECMDB: Hydrogenase-4 component A (P23481)

Identification

Name:

Hydrogenase-4 component A

Synonyms:

Not Available

Gene Name:

hyfA

Enzyme Class:

Not Available

Biological Properties

General Function:

Involved in electron carrier activity

Specific Function:

Probable electron transfer protein for hydrogenase 4

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

EcoCyc Reactions:

1.0

→

1.0

1.0Formic acid + 1.0Hydrogen ion → 1.0Carbon dioxide + 1.0Hydrogen (gas)
ReactionCard

Metabolites:

ECMDB ID	Name	View
ECMDB04030	Carbon dioxide	MetaboCard
ECMDB00142	Formic acid	MetaboCard
ECMDB01362	Hydrogen (gas)	MetaboCard
ECMDB21225	Hydrogen ion	MetaboCard

GO Classification:

Function
binding
electron carrier activity
iron-sulfur cluster binding
metal cluster binding

Gene Properties

Blattner:

b2481

Gene Orientation

Clockwise

Centisome Percentage:

56.02

Left Sequence End

2599223

Right Sequence End

2599840

Gene Sequence:

>618 bp
ATGACAACCCAGTATGGATTTTTTATTGATTCCAGCCGTTGCACCGGTTGCAAAACCTGC
GAGCTGGCCTGTAAAGACTACAAAGATTTGACGCCAGAAGTCAGCTTCCGCCGCATTTAT
GAATATGCTGGCGGCGACTGGCAGGAAGATAACGGTGTCTGGCACCAGAACGTGTTTGCC
TACTATCTGTCGATTTCATGTAACCACTGCGAAGATCCGGCTTGTACTAAAGTCTGCCCG
AGCGGTGCGATGCATAAACGTGAAGATGGTTTTGTTGTGGTCGATGAAGATGTGTGCATT
GGCTGCCGCTACTGCCATATGGCTTGCCCGTATGGCGCACCGCAATATAACGAAACGAAA
GGCCATATGACCAAATGCGATGGTTGTTATGACCGTGTTGCGGAGGGTAAAAAGCCGATC
TGTGTTGAATCTTGTCCGCTGCGGGCGCTGGATTTCGGCCCTATCGACGAGCTGCGTAAA
AAACATGGCGATCTGGCGGCCGTTGCGCCGTTGCCGCGAGCTCACTTTACCAAACCGAAT
ATTGTGATCAAACCCAATGCCAATAGCCGCCCGACCGGGGATACCACTGGCTATCTGGCA
AACCCGAAGGAGGTGTGA

Protein Properties

Pfam Domain Function:

Fer4 (PF00037 )

Protein Residues:

205

Protein Molecular Weight:

22154

Protein Theoretical pI:

Signaling Regions:

None

Transmembrane Regions:

None

Protein Sequence:

>Hydrogenase-4 component A
MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTSTITAPVVCHHCEEAPCL
QVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGSRPVNAHAQYVFQAEGSLK
DGEENAPTQHALLRWEPGVQTVAVKCDLCDFLPEGPACVRACPNQALRLITGDSLQRQMK
EKQRLAASWFANGGEDPLSLTQEQR

References

External Links:

Resource	Link
Uniprot ID:	P23481
Uniprot Name:	HYFA_ECOLI
GenBank Gene ID:	AP009048
Genebank Protein ID:	1651422
Ecogene ID:	EG11150
Ecocyc:	EG11150
ColiBase:	b2481
Kegg Gene:	b2481
EchoBASE ID:	EB1139
CCDB:	HYFA_ECOLI
BacMap:	90111444

General Reference:

Andrews, S. C., Harrison, P. M., Guest, J. R. (1991). "A molecular analysis of the 53.3 minute region of the Escherichia coli linkage map." J Gen Microbiol 137:361-367. Pubmed: 2016588
Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Horiuchi, T., et, a. l. .. (1997). "Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." DNA Res 4:91-113. Pubmed: 9205837