Identification
Name:Putative arsenate reductase
Synonyms:
  • Arsenical pump modifier
Gene Name:yfjU
Enzyme Class:
Biological Properties
General Function:Inorganic ion transport and metabolism
Specific Function:Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of arsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Complex Reactions:
1.0Thumb+1.0glutaredoxin1.0Thumb+1.0glutaredoxin disulfide+1.0Thumb
1.0Arsenate + 1.0glutaredoxin → 1.0Arsenite + 1.0glutaredoxin disulfide + 1.0Water
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21394ArsenateMetaboCard
ECMDB21309ArseniteMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
Not Available
Protein Properties
Pfam Domain Function:
Protein Residues:104
Protein Molecular Weight:11823
Protein Theoretical pI:7
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Putative arsenate reductase
MSNITIYHNPACGTSRNTLEMLHNNGNEPTIINYLDMPPTRDELIKLISDIFSDKIIECI
REQCHLMPALSLNVIGHVDIRSIHSYLFNFNEKVSPSHGFIKNG
References
External Links:
ResourceLink
Uniprot ID:P0CF87
Uniprot Name:ARSCL_ECOLI
CCDB:ARSCL_ECOLI
General Reference:
  • Yamamoto, Y., Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kimura, S., Kitagawa, M., Makino, K., Miki, T., Mitsuhashi, N., Mizobuchi, K., Mori, H., Nakade, S., Nakamura, Y., Nashimoto, H., Oshima, T., Oyama, S., Saito, N., Sampei, G., Satoh, Y., Sivasundaram, S., Tagami, H., Horiuchi, T., et, a. l. .. (1997). "Construction of a contiguous 874-kb sequence of the Escherichia coli -K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features." DNA Res 4:91-113. Pubmed: 9205837